Medical help-seeking intentions among patients with early Alzheimer's disease
Villarejo-Galende, Alberto (Universidad Complutense de Madrid)
García-Arcelay, Elena (Roche Farma)
Piñol-Ripoll, Gerard (Hospital Universitari Santa Maria (Lleida))
Del Olmo-Rodríguez, Antonio (Hospital Universitari Doctor Peset (València))
Viñuela, Félix (Hospital Universitario Virgen Macarena (Sevilla, Andalusia))
Boada, Mercè (Ace Alzheimer Center Barcelona)
Franco-Macías, Emilio (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia))
Ibañez de la Peña, Almudena (Policlínica Guipúzcoa)
Riverol, Mario (Clínica Universidad de Navarra)
Puig-Pijoan, Albert (Hospital del Mar (Barcelona, Catalunya))
Abizanda-Soler, Pedro (Complejo Hospitalario Universitario de Albacete)
Arroyo, Rafael (Hospital Universitario Quirónsalud)
Baquero-Toledo, Miquel (Hospital Universitari i Politècnic La Fe (València))
Feria-Vilar, Inmaculada (Complejo Hospitalario Universitario de Albacete)
Balasa, Mircea (Hospital Clínic i Provincial de Barcelona)
Berbel, Ángel (Hospital Central de la Cruz Roja)
Rodríguez-Rodríguez, Eloy (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria))
Vieira-Campos, Alba (Hospital Universitario de la Princesa (Madrid))
García-Ribas, Guillermo (Hospital Universitario Ramón y Cajal (Madrid))
Rodrigo-Herrero, Silvia (Hospital Universitario Juan Ramón Jiménez)
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau)
Maurino, Jorge (Roche Farma)
Universitat Autònoma de Barcelona

Data:	2023
Resum:	Limited information is available on the active process of seeking medical help in patients with Alzheimer's disease (AD) at early stages. The aim of this study was to assess the phenomenon of medical help-seeking in early AD and to identify associated factors. A multicenter, non-interventional study was conducted including patients of 50-90 years of age with prodromal or mild AD (National Institute on Aging/Alzheimer's Association criteria), a Mini-Mental State Examination (MMSE) score ≥ 22, and a Clinical Dementia Rating-Global score (CDR-GS) of 0. 5-1. 0. A multivariate logistic regression analysis was conducted. A total of 149 patients were included. Mean age (SD) was 72. 3 (7. 0) years, 50. 3% were female, and 87. 2% had a CDR-GS score of 0. 5. Mean disease duration was 1. 4 (1. 8) years. Ninety-four (63. 1%) patients sought medical help, mostly from neurologists. Patients with help-seeking intentions were mostly female (60. 6%) with a CDR-GS score of 0. 5 (91. 5%) and had a greater awareness of diagnosis, poorer quality of life, more depressive symptoms, and a more severe perception of their condition than their counterparts. Lack of help-seeking intentions was associated with male sex (p = 0. 003), fewer years of education (p = 0. 005), a low awareness of diagnosis (p = 0. 005), and a low emotional consequence of the condition (p = 0. 016). Understanding the phenomenon of active medical help-seeking may facilitate the design of specific strategies to improve the detection of cognitive impairment, especially in patients with a lower level of educational attainment and poor awareness of their condition.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Alzheimer's disease ; Awareness ; Early diagnosis ; Help-seeking ; Illness representation
Publicat a:	Frontiers in psychiatry, Vol. 14 (2023) , p. 1290002, ISSN 1664-0640

DOI: 10.3389/fpsyt.2023.1290002
PMID: 38173708

6 p, 290.0 KB

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