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1.
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11 p, 1.0 MB |
Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study
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Balk, Lisanne J. (Vrije Universiteit Amsterdam) ;
Coric, Danko (Vrije Universiteit Amsterdam) ;
Knier, Benjamin (Technische Universität München) ;
Zimmermann, Hanna G. (Charité - Universitätsmedizin Berlin) ;
Behbehani, Raed (Ibn Sina Hospital, Kuwait) ;
Alroughani, Raed (Amiri Hospital, Kuwait) ;
Martinez-Lapiscina, Elena H. (Hospital Clínic i Provincial de Barcelona) ;
Brandt, Alexander U. (Charité - Universitätsmedizin Berlin) ;
Sánchez-Dalmau, Bernardo (Hospital Clínic i Provincial de Barcelona) ;
Vidal-Jordana, Angela (Hospital Universitari Vall d'Hebron) ;
Albrecht, Philipp (Heinrich Heine University) ;
Koska, Valeria (Heinrich Heine University) ;
Havla, Joachim (Ludwig-Maximilians Universitaet Muenchen) ;
Pisa, Marco (Vita-Salute San Raffaele University) ;
Nolan, Rachel C. (New York University School of Medicine) ;
Leocani, Letizia (Vita-Salute San Raffaele University) ;
Paul, Friedemann (Max Delbrueck Center for Molecular Medicine and Charité - Universitätsmedizin Berlin) ;
Aktas, Orhan (Heinrich Heine University) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Balcer, Laura J. (New York University School of Medicine) ;
Villoslada, Pablo (Hospital Clínic i Provincial de Barcelona) ;
Outteryck, Olivier (Université Lille) ;
Korn, Thomas (Munich Cluster for Systems Neurology (SyNergy)) ;
Petzold, Axel (Moorfields Eye Hospital & The National Hospital for Neurology and Neurosurgery) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background: The association of peripapillary retinal nerve fibre layer (pRNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness with neurodegeneration in multiple sclerosis (MS) is well established. [...]
2019 -  10.1177/2055217319871582
Multiple Sclerosis Journal - Experimental, Translational and Clinical, Vol. 5 Núm. 3 (2019)
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2.
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9 p, 1.1 MB |
Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis
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Meaton, Isobel (University of Nottingham) ;
Altokhis, Amjad (University of Nottingham) ;
Allen, Christopher Martin (University of Nottingham) ;
Clarke, Margareta A. (Vanderbilt University) ;
Sinnecker, Timm (University Basel) ;
Meier, Dominik (University Basel) ;
Enzinger, Christian (Medical University of Graz) ;
Calabrese, Massimiliano (University of Verona) ;
De Stefano, Nicola (University of Siena) ;
Pitiot, Alain (Laboratory of Image and Data Analysis (Regne Unit)) ;
Giorgio, Antonio (University of Siena) ;
Schoonheim, Menno M. (Universiteit Amsterdam) ;
Paul, Friedemann (Charité - Universitätsmedizin Berlin) ;
Pawlak, Mikolaj A. (Poznan University of Medical Sciences) ;
Schmidt, Reinhold (Medical University of Graz) ;
Granziera, Cristina (University of Basel) ;
Kappos, Ludwig (University of Basel) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron) ;
Wuerfel, Jens (Charité - Universitätsmedizin Berlin) ;
Evangelou, Nikos (University of Nottingham) ;
Universitat Autònoma de Barcelona
White matter lesions (WMLs) on brain magnetic resonance imaging (MRI) in multiple sclerosis (MS) may contribute to misdiagnosis. In chronic active lesions, peripheral iron-laden macrophages appear as paramagnetic rim lesions (PRLs). [...]
2022 - 10.1177/13524585221118677
Multiple sclerosis, Vol. 28 (august 2022) , p. 2212-2220
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3.
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16 p, 3.3 MB |
Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis
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Bernardo-Faura, Martí (Centre de Recerca en Agrigenòmica) ;
Rinas, Melanie (Rwth Aachen University. Joint Research Center for Computational Biomedicine) ;
Wirbel, Jakob (Rwth Aachen University. Joint Research Center for Computational Biomedicine) ;
Pertsovskaya, Inna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pliaka, Vicky (School of Mechanical Engineering, National Technical University of Athens) ;
Messinis, Dimitris E. (ProtATonce) ;
Vila, Gemma (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Sakellaropoulos, Theodore (National Technical University of Athens) ;
Faigle, Wolfgang (University of Zurich) ;
Stridh, Pernilla (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ;
Behrens, Janina R. (Charité University Medicine Berlin. NeuroCure Clinical Research Center and Department of Neurology) ;
Olsson, Tomas (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ;
Martin, Roland (University Hospital Zurich (Suïssa)) ;
Paul, Friedemann (Charité University Medicine Berlin. NeuroCure Clinical Research Center and Department of Neurology) ;
Alexopoulos, Leonidas G. (ProtATonce) ;
Villoslada, Pablo (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Saez-Rodriguez, Julio (Heidelberg University Hospital (Alemanya))
Multiple sclerosis (MS) is a major health problem, leading to a significant disability and patient suffering. Although chronic activation of the immune system is a hallmark of the disease, its pathogenesis is poorly understood, while current treatments only ameliorate the disease and may produce severe side effects. [...]
2021 - 10.1186/s13073-021-00925-8
Genome Medicine, Vol. 13 (July 2021) , art. 117
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4.
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11 p, 5.6 MB |
New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab
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Toboso, Inmaculada (Hospital Universitario Ramón y Cajal (Madrid)) ;
Tejeda-Velarde, Amalia (Hospital Universitario Ramón y Cajal (Madrid)) ;
Alvarez-Lafuente, Roberto (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Arroyo, Rafael (Hospital Universitario Quiron Salud) ;
Hegen, Harald (Medical University of Innsbruck) ;
Deisenhammer, Florian (Medical University of Innsbruck) ;
Sainz de la Maza, Susana (Hospital Universitario Ramón y Cajal (Madrid)) ;
Alvarez-Cermeño, José C. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Izquierdo, Guillermo (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Paramo, Dolores (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Oliva, Pedro (Hospital Universitario Central de Asturias) ;
Casanova, Bonaventura (Hospital Universitari i Politècnic La Fe (València)) ;
Agüera-Morales, Eduardo (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Franciotta, Diego (Istituti di Recovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation) ;
Gastaldi, Matteo (Istituti di Recovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation) ;
Fernández, Oscar (Hospital Regional Universitario de Málaga) ;
Urbaneja, Patricia (Hospital Regional Universitario de Málaga) ;
Garcia-Dominguez, José M. (Hospital General Universitario Gregorio Marañón) ;
Romero, Fernando (Hospital General Universitario Gregorio Marañón) ;
Laroni, Alicia (University of Genoa, Ospedale Policlinico San Martino) ;
Uccelli, Antonio (University of Genoa, Ospedale Policlinico San Martino) ;
Perez-Sempere, Angel (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Saiz, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Blanco, Yolanda (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Galimberti, Daniela (University of Milan) ;
Scarpini, Elio (University of Milan) ;
Espejo, Carmen (Hospital Universitari Vall d'Hebron) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Rasche, Ludwig (Humboldt-Universität zu Berlin) ;
Paul, Friedemann (Charité - Universitätsmedizin Berlin) ;
González, Inés (Hospital Álvaro Cunqueiro (Vigo)) ;
Álvarez, Elena (Hospital Álvaro Cunqueiro (Vigo)) ;
Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Caminero, Ana B. (Hospital Nuestra Señora de Sonsoles (Àvila)) ;
Aladro, Yolanda (Hospital Universitario Getafe) ;
Calles, Carmen (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Eguía, Pablo (Hospital Doctor Jose Molina Orosa) ;
Belenguer-Benavides, Antonio (Consorci Hospitalari Provincial de Castelló) ;
Ramió-Torrentà, Lluís (Hospital Universitari de Girona Doctor Josep Trueta) ;
Quintana, Ester (Hospital Universitari de Girona Doctor Josep Trueta) ;
Martínez-Rodríguez, José E. (Hospital del Mar (Barcelona, Catalunya)) ;
Oterino, Agustín (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
López de Silanes, Carlos (Hospital Universitario de Torrejón) ;
Casanova, Luis I. (Hospital Universitario de Torrejón) ;
Landete Pascual, Lamberto (Hospital Universitari Doctor Peset (València)) ;
Frederiksen, Jette (Glostrup University Hospital Copenhagen) ;
Bsteh, Gabriel (Medical University of Innsbruck) ;
Mulero, P. (Hospital Universitari Vall d'Hebron) ;
Comabella, Manuel (Hospital Universitari Vall d'Hebron) ;
Hernández, Miguel A. (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Espiño, Mercedes (Hospital Universitario Ramón y Cajal (Madrid)) ;
Prieto, José M. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Pérez, Domingo (Hospital del Bierzo (Ponferrada, Lleó)) ;
Otano, María (Complejo Hospitalario de Navarra) ;
Padilla, Francisco (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
García-Merino, Juan A. (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Navarro Cantó, Laura (Hospital General Universitario de Elche) ;
Muriel, Alfonso (Hospital Universitario Ramón y Cajal (Madrid)) ;
Frossard, Lucienne Costa (Hospital Universitario Ramón y Cajal (Madrid)) ;
Villar, Luisa M. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Universitat Autònoma de Barcelona
Overview: We assessed the role of age and disease activity as new factors contributing to establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis patients treated with natalizumab in 36 University Hospitals in Europe. [...]
2020 - 10.3389/fneur.2020.579438
Frontiers in neurology, Vol. 11 (december 2020)
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5.
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11 p, 1.3 MB |
Multicentre comparison of a diagnostic assay : aquaporin-4 antibodies in neuromyelitis optica
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Waters, Patrick (University of Oxford) ;
Reindl, Markus (Medical University of Innsbruck) ;
Saiz, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Schanda, Kathrin (Medical University of Innsbruck) ;
Tuller, Friederike (Medical University of Innsbruck) ;
Kral, Vlastimil (Zdravotni ustav se sidlem v Usti nad Labem, Centrum imunologie a mikrobiologie) ;
Nytrova, Petra (Charles University. Faculty of Medicine in Hradec Králové) ;
Sobek, Ondrej (Topelex Ltd) ;
Nielsen, Helle Hvilsted (Odense University Hospital (Dinamarca)) ;
Barington, Torben (Odense University Hospital (Dinamarca)) ;
Lillevang, Søren T. (Odense University Hospital (Dinamarca)) ;
Illes, Zsolt (University of Pécs) ;
Rentzsch, Kristin (Euroimmun AG) ;
Berthele, Achim (Klinikum rechts der Isar der TU München, Klinik für Neurologie) ;
Berki, Tímea (University of Pécs) ;
Granieri, Letizia (Neuroscience Institute Cavalieri Ottolenghi (NICO), University Hospital San Luigi Gonzaga, Regional Referring Multiple Sclerosis Centre) ;
Bertolotto, Antonio (Neuroscience Institute Cavalieri Ottolenghi (NICO), University Hospital San Luigi Gonzaga, Regional Referring Multiple Sclerosis Centre) ;
Giometto, Bruno (Azienda ULSS 9 Treviso) ;
Zuliani, Luigi (Azienda ULSS 9 Treviso) ;
Hamann, Dörte (Sanquin Diagnostic Services, Department of Immunopathology and Blood Coagulation, Amsterdam) ;
van Pelt, E. Daniëlle (MS Centre ErasMS, Erasmus MC) ;
Hintzen, Rogier (MS Centre ErasMS, Erasmus MC) ;
Höftberger, Romana (Medical University of Vienna. Institute of Neurology) ;
Costa, Carme (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Comabella, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tintoré, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Siva, Aksel (Istanbul University, Cerrahpasa Medical School) ;
Altintas, Ayse (Istanbul University, Cerrahpasa Medical School) ;
Deniz, Günnur (Istanbul University, Institute of Experimental Medicine) ;
Woodhall, Mark (University of Oxford) ;
Palace, Jacqueline (University of Oxford) ;
Paul, Friedemann (Charité - Universitätsmedizin Berlin) ;
Hartung, Hans-Peter (Heinrich-Heine-University Düsseldorf) ;
Aktas, Orhan (Heinrich-Heine-University Düsseldorf) ;
Jarius, Sven (University of Heidelberg) ;
Wildemann, Brigitte (University of Heidelberg) ;
Vedeler, Christian (Haukeland University Hospital (Bergen, Noruega)) ;
Ruiz, Anne (Lyon Neurosciences Research Centre, Neuro-inflammation and Neuro-oncology Team) ;
Leite, M. Isabel (University of Oxford) ;
Trillenberg, Peter (Universitätsklinikum Schleswig-Holstein (Alemanya)) ;
Probst, Monika (Institute for Quality Assurance) ;
Saschenbrecker, Sandra (Euroimmun AG) ;
Vincent, Angela (University of Oxford) ;
Marignier, Romain (Lyon Neurosciences Research Centre, Neuro-inflammation and Neuro-oncology Team) ;
Universitat Autònoma de Barcelona
Antibodies to cell surface central nervous system proteins help to diagnose conditions which often respond to immunotherapies. The assessment of antibody assays needs to reflect their clinical utility. [...]
2016 - 10.1136/jnnp-2015-312601
Journal of Neurology, Neurosurgery, and Psychiatry, Vol. 87 (april 2016) , p. 1005-1015
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