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15 p, 517.3 KB |
GRECOS project (Genotyping Recurrence Risk of Stroke). The use of genetics to predict the vascular recurrence after stroke
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Fernández Cadenas, Israel (Hospital Universitari Vall d'Hebron) ;
Mendióroz, Maite (Hospital Universitari Vall d'Hebron) ;
Giralt, Dolors (Hospital Universitari Vall d'Hebron) ;
Nafría, Cristina (Hospital Universitari Vall d'Hebron) ;
Garcia, Elena (Fundació Docència i Recerca Mutua Terrassa) ;
Carrera, Caty (Hospital Universitari Vall d'Hebron) ;
Gallego-Fabrega, Cristina (Fundació Docència i Recerca Mutua Terrassa) ;
Domingues-Montanari, Sophie (Hospital Universitari Vall d'Hebron) ;
Delgado, Pilar (Hospital Universitari Vall d'Hebron) ;
Ribó, Marc (Hospital Universitari Vall d'Hebron) ;
Castellanos, Mar (Hospital Universitari Dr. Josep Trueta. Departament de Neurologia) ;
Martínez, Sergi (Institut d'Investigació Biomèdica Sant Pau) ;
Freijo, Mari Mar (Hospital de Basurto. Departamento de Neurologia) ;
Jiménez-Conde, Jordi (Hospital del Mar. Departament de Neurologia) ;
Rubiera, Marta (Hospital Universitari Vall d'Hebron) ;
Alvarez Sabín, José (Hospital Universitari Vall d'Hebron) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron) ;
Font, Maria Angels (Hospital de Bellvitge. Departament de Neurologia) ;
Grau Olivares, Marta (Hospital Universitari Sagrat Cor. Departament de Neurologia) ;
Palomeras, Ernest (Hospital de Mataró. Departament de Neurologia) ;
Perez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martinez Zabaleta, Maite (Hospital Donostia. Departamento de Neurologia) ;
Masjuan, Jaime (Hospital Ramon y Cajal. Departamento de Neurologia) ;
Moniche, Francisco (Hospital Universitario Virgen del Rocío. Departamento de Neurologia) ;
Canovas, David (Institut d'Investigació i Innovació Parc Taulí. Departament de Neurologia) ;
Piñana, Carlos (Hospital Universitario Virgen de las Nieves. Departamento de Neurologia) ;
Purroy, Francisco (Hospital Universitari Arnau de Vilanova. Departament de Neurologia) ;
Cocho, Dolores (Hospital de Granollers. Departament de Neurologia) ;
Navas, Inma (Hospital Mútua de Terrassa. Departament de Neurologia) ;
Tejero, Carlos (Hospital Clínico Universitario Lozano Blesa. Departamento de Neurologia) ;
Aymerich, Nuria (Hospital de Navarra. Departamento de Neurologia) ;
Cullell, Natalia (Fundació Docència i Recerca Mutua Terrassa) ;
Muiño, Elena (Fundació Docència i Recerca Mutua Terrassa) ;
Serena, Joaquín (Hospital Universitari Dr. Josep Trueta. Departament de Neurologia) ;
Rubio, Francisco (Hospital de Bellvitge. Departament de Neurologia) ;
Davalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roquer González, Jaume (Hospital del Mar. Departament de Neurologia) ;
Arenillas Lara, Juan Francisco (Hospital Clínico Universitario de Valladolid. Departamento de Neurologia) ;
Martí Fábregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Keene, Keith (Center for Health Disparities. East Carolina University) ;
Chen, Wei-Min (Department of Public Health Sciences; Center for Public Health Genomics, University of Virginia) ;
Worrall, Bradford (Department of Neurology; Department of Public Health Sciences, University of Virginia) ;
Sale, Michele (Center for Public Health Genomics, University of Virginia) ;
Arboix, Adrià (Hospital Universitari Sagrat Cor. Departament de Neurologia) ;
Krupinski, Jerzy (Hospital Mútua de Terrassa. Departament de Neurologia) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron) ;
GRECOSstudy group ;
Universitat Autònoma de Barcelona
Background and Purpose-Vascular recurrence occurs in 11% of patients during the first year after ischemic stroke (IS) or transient ischemic attack (TIA). Clinical scores do not predict the whole vascular recurrence risk, therefore we aimed to find genetic variants associated with recurrence that might improve the clinical predictive mode is in IS. [...]
2017 -  10.1161/STROKEAHA.116.014322
Stroke, Vol. 48 Núm. 5 (2017) , p. 1147-1153
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6 p, 210.4 KB |
Circulating cell-free DNA is a predictor of short-term neurological outcome in stroke patients treated with intravenous thrombolysis
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Bustamante, Alejandro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mancha, Fernando (Stroke Program, Institute of Biomedicine of Seville, Hospital Universitario Virgen del Rocio, Seville, Spain) ;
Macher, Hada C (Department of Clinical Biochemistry, Hospital Universitario Virgen del Rocio (IBiS/CSIC/SAS/University of Seville), Seville, Spain) ;
García-Berrocoso, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Giralt, Dolors (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribó, Marc (Hospital Universitari Vall d'Hebron) ;
Guerrero, Juan M (Department of Clinical Biochemistry, Hospital Universitario Virgen del Rocio (IBiS/CSIC/SAS/University of Seville), Seville, Spain) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Circulating cell-free DNA (cfDNA) has been described as a prognostic marker for several diseases. Its prognostic value for short-term outcome in stroke patients treated with intravenous thrombolysis remains unexplored. [...]
2016 - 10.1177/1849454416668791
Journal of Circulating Biomarkers, Vol. 5 (september 2016)
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7 p, 1.2 MB |
The angiogenic gene profile of circulating endothelial progenitor cells from ischemic stroke patients
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Navarro-Sobrino, Míriam (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández-Guillamon, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribó, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Romero, Ignacio A (Department of Life Sciences, The Open University, Milton Keynes, UK) ;
Couraud, Pierre-Olivier (Division of Hematology and Medical Oncology, Institut Cochin, Université Paris Descartes, Paris, France) ;
Weksler, Babette Barbash (Weill Medical College of Cornell University, New York, NY, USA) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosell, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
The identification of circulating endothelial progenitor cells (EPCs) has introduced new possibilities for cell-based treatments for stroke. We tested the angiogenic gene expression of outgrowth endothelial cells (OECs), an EPC subtype capable to shape vessel structures. [...]
2013 - 10.1186/2045-824X-5-3
Vascular Cell, Vol. 5 (february 2013) , p. 3
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11 p, 870.1 KB |
Brain Perihematoma Genomic Profile Following Spontaneous Human Intracerebral Hemorrhage
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Rosell, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilalta, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-Berrocoso, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fernández-Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Domingues-Montanari, Sophie (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cuadrado, Eloy (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Delgado, Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribó, Marc (Hospital Universitari Vall d'Hebron) ;
Martínez-Sáez, Elena (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Ortega-Aznar, Arantxa (Hospital Universitari Vall d'Hebron) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron)
Spontaneous intracerebral hemorrhage (ICH) represents about 15% of all strokes and is associated with high mortality rates. Our aim was to identify the gene expression changes and biological pathways altered in the brain following ICH. [...]
2011 - 10.1371/journal.pone.0016750
PloS one, Vol. 6 (february 2011)
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12 p, 919.1 KB |
A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation
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Castro, Jessica (Universitat de Girona. Departament de Biologia) ;
Ribó i Panosa, Marc (Universitat de Girona. Departament de Biologia) ;
Navarro, Susana (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Nogués i Bara, M. Victòria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Vilanova i Brugués, Maria (Universitat de Girona. Departament de Biologia) ;
Benito i Mundet, Antoni (Universitat de Girona. Departament de Biologia)
Background: Ribonucleases are promising agents for use in anticancer therapy. Among the different ribonucleases described to be cytotoxic, a paradigmatic example is onconase which manifests cytotoxic and cytostatic effects, presents synergism with several kinds of anticancer drugs and is currently in phase II/III of its clinical trial as an anticancer drug against different types of cancer. [...]
2011 - 10.1186/1471-2407-11-9
BMC Cancer, Vol. 11, N. 9 (January 2011) , p. 1-12
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