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35 p, 18.8 MB |
A saturated map of common genetic variants associated with human height
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Yengo, Loic (The University of Queensland) ;
Vedantam, Sailaja (Program in Medical and Population Genetics. Broad Institute of MIT and Harvard) ;
Marouli, Eirini (William Harvey Research Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ;
Sidorenko, Julia (Institute for Molecular Bioscience. The University of Queensland) ;
Bartell, Eric (Harvard Medical School) ;
Sakaue, Saori (righam and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Graff, Marielisa (Gillings School of Global Public Health. University of North Carolina at Chapel Hill) ;
Eliasen, Anders U. (Section for Bioinformatics. Department of Health Technology. Technical University of Denmark) ;
Jiang, Yunxuan (23andMe) ;
Raghavan, Sridharan (Division of Biomedical Informatics and Personalized Medicine) ;
Miao, Jenkai (Broad Institute of MIT and Harvard) ;
Arias, Joshua D. (National Cancer Institute) ;
Graham, Sarah E. (University of Michigan) ;
Mukamel, Ronen E. (Harvard Medical School) ;
Spracklen, Cassandra N. (University of Massachusetts) ;
Yin, Xianyong (University of Michigan School of Public Health) ;
Chen, Shyh-Huei (Wake Forest School of Medicine) ;
Ferreira, Teresa (University of Oxford) ;
Highland, Heather H. (University of North Carolina at Chapel Hill) ;
Ji, Yingjie (University of Exeter) ;
Karaderi, Tugce (University of Oxford) ;
Lin, Kuang (Nuffield University of Oxford) ;
Lüll, Kreete (University of Tartu) ;
Malden, Deborah (University of Oxford) ;
Medina-Gomez, Carolina (University Medical Center Rotterdam) ;
Machado, Moara (National Cancer Institute) ;
Moore, Amy (RTI International) ;
Rüeger, Sina (Swiss Institute of Bioinformatics) ;
Sim, Xueling (National University of Singapore) ;
Vrieze, Scott (University of Minnesota) ;
Ahluwalia, Tarunveer Singh (University of Copenhagen) ;
Akiyama, Masato (Kyushu University) ;
Allison, Matthew A. (University of California (San Diego, Estats Units)) ;
Álvarez, Marcus (David Geffen School of Medicine) ;
Andersen, Mette korre (University of Copenhagen) ;
Ani, Alireza (Isfahan University of Medical Sciences) ;
Appadurai, Vivek (Copenhagen University Hospital) ;
Arbeeva, Liubov (University of North Carolina) ;
Bhaskar, Seema (CSIR-Centre for Cellular and Molecular Biology) ;
Bielak, Lawrence F. (University of Michigan School of Public Health) ;
Bollepalli, Sailalitha (University of Helsinki) ;
Bonnycastle, Lori L. (National Institutes of Health) ;
Bork-Jensen, Jette (University of Copenhagen) ;
Bradfield, J.P. (Quantinuum Research) ;
Bradford, Y. (University of Pennsylvania) ;
Braund, P.S. (Glenfield Hospital) ;
Brody, J.A. (University of Washington) ;
Burgdorf, K.S. (Copenhagen University) ;
Cade, B.E. (Brigham and Women's Hospital) ;
Cai, H. (Vanderbilt University Medical Center) ;
Cai, Q. (Vanderbilt University Medical Center) ;
Campbell, Archie (University of Edinburgh) ;
Cañadas-Garre, M. (Queen's University of Belfast) ;
Catamo, E. (Burlo Garofolo) ;
Chai, J.F. (National University of Singapore and National University Health System) ;
Chai, X. (National University of Singapore and National University Health System) ;
Chang, L.C. (Academia Sinica) ;
Chang, Y.C. (National Taiwan University Hospital) ;
Chen, C.H. (Academia Sinica) ;
Chesi, A. (Children's Hospital of Philadelphia) ;
Choi, S.H. (Broad Institute of MIT and Harvard) ;
Chung, R.H. (National Health Research Institutes) ;
Cocca, M. (Burlo Garofolo) ;
Concas, M.P. (Burlo Garofolo) ;
Couture, C. (Université Laval) ;
Cuellar-Partida, Gabriel (University of Queensland Diamantina Institute) ;
Danning, R. (Brigham and Women's Hospital) ;
Daw, E.W. (Washington University School of Medicine) ;
Degenhard, F. (Christian-Albrechts University of Kiel) ;
Delgado, G.E. (Heidelberg University) ;
Delitala, A. (Università degli Studi di Sassari) ;
Demirkan, A. (University of Surrey) ;
Deng, X. (Boston University School of Public Health) ;
Devineni, P. (VA Boston Healthcare System) ;
Dietl, A. (University Hospital Regensburg) ;
Dimitriou, M. (Harokopio University of Athens) ;
Dimitrov, L. (Medical Center Boulevard) ;
Dorajoo, R. (Duke-NUS Medical School) ;
Ekici, A.B. (Friedrich-Alexander-Universität Erlangen-Nürnberg) ;
Engmann, J.E. (University College London) ;
Fairhurst-Hunter, Z. (University of Oxford) ;
Farmaki, A.E. (Harokopio University of Athens) ;
Faul, J.D. (University of Michigan) ;
Fernandez-Lopez, J.C. (National Institute of Genomic Medicine) ;
Forer, L. (Medical University of Innsbruck) ;
Francescatto, M. (University of Trieste) ;
Freitag-Wolf, S. (Kiel University) ;
Fuchsberger, C. (Affiliated Institute of the University of Lübeck) ;
Galesloot, T.E. (Radboud University Medical Center) ;
Gao, Y. (University of Mississippi) ;
Gao, Z. (Helmholtz Zentrum München Research Center for Environmental Health) ;
Geller, F. (Statens Serum Institut) ;
Giannakopoulou, O. (Queen Mary University of London) ;
Giulianini, F. (Brigham and Women's Hospital) ;
Gjesing, A.P. (University of Copenhagen) ;
Goel, A. (University of Oxford) ;
Gordon, S.D. (QIMR Berghofer Medical Research Institute) ;
Gorski, M. (University of Regensburg) ;
Grove, J. (Aarhus University) ;
Guo, X. (Harbor-UCLA Medical Center) ;
Gustafsson, S. (Uppsala University) ;
Haessler, J. (Fred Hutchinson Cancer Research Center) ;
Hansen, T.F. (Copenhagen University Hospital) ;
Havulinna, A.S. (Finnish Institute for Health and Welfare) ;
Haworth, S.J. (University of Bristol) ;
He, J. (Vanderbilt University Medical Center) ;
Heard-Costa, N. (Framingham Heart Study) ;
Hebbar, P. (Dasman Diabetes Institute) ;
Hindy, G. (Lund University) ;
Ho, Y.L.A. (Veterans Affairs Boston Healthcare System) ;
Hofer, E. (Medical University of Graz) ;
Holliday, E. (University of Newcastle) ;
Horn, K. (University of Leipzig) ;
Hornsby, W.E. (University of Michigan) ;
Hottenga, J.J. (Vrije Universiteit Amsterdam) ;
Huang, H. (Chan School of Public Health) ;
Huang, J. (Peking University) ;
Huerta-Chagoya, A. (Instituto Nacional de Ciencias Médicas y Nutrición) ;
Huffman, J.E. (Veterans Affairs Boston Healthcare System) ;
Hung, Y.J. (Tri-Service General Hospital Songshan Branch) ;
Huo, S. (Chinese Academy of Sciences) ;
Hwang, M.Y. (National Institute of Health) ;
Iha, H. (Otsuka Pharmaceutical Co.) ;
Ikeda, D.D. (Otsuka Pharmaceutical Co.) ;
Isono, M. (National Center for Global Health and Medicine) ;
Jackson, A.U. (University of Michigan School of Public Health) ;
Jäger, S. (German Center for Diabetes Research (DZD)) ;
Jansen, I.E. (Vrije Universiteit Medical Center) ;
Johansson, I. (Umeå University) ;
Jonas, J.B. (Capital Medical University) ;
Jonsson, A. (University of Copenhagen) ;
Jørgensen, T. (University of Copenhagen) ;
Kalafati, I.P. (Harokopio University of Athens) ;
Kanai, M. (Osaka University Graduate School of Medicine) ;
Kanoni, S. (Queen Mary University of London) ;
Kårhus, L.L. (Copenhagen University Hospital) ;
Kasturiratne, A. (University of Kelaniya) ;
Katsuya, T. (Osaka University Graduate School of Medicine) ;
Kawaguchi, T. (Kyoto University Graduate School of Medicine) ;
Kember, R.L. (University of Pennsylvania) ;
Kentistou, K.A. (University of Edinburgh) ;
Kim, H.N. (Sungkyunkwan University) ;
Kim, Y.J. (National Institute of Health) ;
Kleber, M.E. (SYNLAB MVZ Humangenetik Mannheim) ;
Knol, M.J. (University Medical Center Rotterdam) ;
Kurbasic, A. (Lund University) ;
Lauzon, M. (Harbor-UCLA Medical Center) ;
Le, P. (University of Toronto at Mississauga) ;
Lea, R. (Queensland University of Technology) ;
Lee, J.Y. (Soonchunhyang Mirai Medical Center) ;
Leonard, H.L. (Data Tecnica International) ;
Li, S.A. (Leidos Biomedical Research) ;
Li, X. (St Cloud State University) ;
Liang, J. (Case Western Reserve University) ;
Lin, H. (University of Massachusetts Chan Medical School) ;
Lin, S.Y. (Taichung Veterans General Hospital) ;
Liu, J. (Genome Institute of Singapore) ;
Liu, X. (Statens Serum Institut) ;
Lo, K.S. (Montreal Heart Institute) ;
Long, J. (Vanderbilt University Medical Center) ;
Lores-Motta, L. (Radboud University Nijmegen Medical Center) ;
Luan, J. (University of Cambridge School of Clinical Medicine) ;
Lyssenko, V. (Lund University Diabetes Centre) ;
Lyytikäinen, L.P. (Tampere University Hospital) ;
Mahajan, A. (RIKEN Center for Integrative Medical Sciences) ;
Mamakou, V. (National and Kapodistrian University of Athens) ;
Mangino, M. (Guy's and St Thomas' Foundation Trust) ;
Manichaikul, A. (University of Virginia School of Medicine) ;
Marten, J. (University of Edinburgh) ;
Mattheisen, M. (University Hospital) ;
Mavarani, L. (University Hospital Essen) ;
McDaid, A.F. (Swiss Institute of Bioinformatics) ;
Meidtner, K. (German Center for Diabetes Research) ;
Melendez, T.L. (University of Michigan) ;
Mercader, J.M. (Massachusetts General Hospital) ;
Milaneschi, Y. (Amsterdam UMC and Vrije Universiteit) ;
Miller, J.E. (University of Pennsylvania) ;
Millwood, I.Y. (University of Oxford) ;
Mishra, P.P. (Tampere University) ;
Mitchell, R.E. (University of Bristol) ;
Møllehave, L.T. (Copenhagen University Hospital) ;
Morgan, A. (Burlo Garofolo) ;
Mucha, S. (University of Lübeck) ;
Munz, M. (University of Lübeck) ;
Nakatochi, M. (Nagoya University Graduate School of Medicine) ;
Nelson, C.P. (Glenfield Hospital) ;
Nethander, M. (University of Gothenburg) ;
Nho, C.W. (Gangneung Institute of Natural Products) ;
Nielsen, A.A. (Lillebaelt Hospital) ;
Nolte, I.M. (University Medical Center Groningen) ;
Nongmaithem, S.S. (Wellcome Sanger Institute) ;
Noordam, R. (Leiden University Medical Center) ;
Ntalla, I. (Queen Mary University of London) ;
Nutile, T. (Institute of Genetics and Biophysics A. Buzzati-Traverso) ;
Pandit, A. (University of Michigan School of Public Health) ;
Christofidou, P. (King's College London) ;
Pärna, K. (University Medical Center Groningen) ;
Pauper, M. (Radboud University Nijmegen Medical Center) ;
Petersen, E.R.B. (Hospital of Southern Jutland) ;
Petersen, L.V. (University of Aarhus) ;
Pitkänen, N. (University of Turku) ;
Polašek, O. (Algebra University College) ;
Poveda, A. (Lund University) ;
Preuss, M.H. (Icahn School of Medicine at Mount Sinai) ;
Pyarajan, S. (VA Boston Healthcare System) ;
Raffield, L.M. (University of North Carolina at Chapel Hill) ;
Rakugi, H. (Osaka University Graduate School of Medicine) ;
Ramirez, J. (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Rasheed, A. (Center for Non-Communicable Diseases) ;
Raven, D. (University of Groningen) ;
Rayner, N.W. (University of Oxford. Churchill Hospital) ;
Riveros, C. (The University of Newcastle) ;
Rohde, R. (University of North Carolina at Chapel Hill) ;
Ruggiero, D. (IRCCS Neuromed) ;
Ruotsalainen, S.E. (University of Helsinki) ;
Ryan, K.A. (University of Maryland School of Medicine) ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Saxena, R. (Massachusetts General Hospital) ;
Scholz, M. (University of Leipzig) ;
Sendamarai, A. (VA Boston Healthcare System) ;
Shen, B. (National Institutes of Health) ;
Shi, J. (23andMe) ;
Shin, J.H. (Hallym University) ;
Sidore, C. (Consiglio Nazionale delle Ricerche (CNR)) ;
Sitlani, Collen M (University of Washington) ;
Slieker, R.C. (Amsterdam Cardiovascular Sciences) ;
Smit, R.A.J. (Leiden University Medical Center) ;
Smith, A.V. (Icelandic Heart Association) ;
Smith, J.A. (University of Michigan) ;
Smyth, L.J. (Queen's University of Belfast) ;
Southam, L. (Wellcome Trust Sanger Institute (Regne Unit)) ;
Steinthorsdottir, V. (deCODE Genetics/Amgen) ;
Sun, L. (University of Chinese Academy of Sciences) ;
Takeuchi, F. (National Center for Global Health and Medicine) ;
Tallapragada, D.S.P. (University of Bergen) ;
Taylor, K.D. (Harbor-UCLA Medical Center) ;
Tayo, B.O. (Loyola University Chicago) ;
Tcheandjieu, C. (Stanford University School of Medicine) ;
Terzikhan, N. (University Medical Center Rotterdam) ;
Tesolin, P. (University of Trieste) ;
Teumer, A. (DZHK (German Centre for Cardiovascular Research)) ;
Theusch, E. (University of California) ;
Thompson, D.J. (University of Cambridge) ;
Thorleifsson, G. (deCODE Genetics/Amgen) ;
Timmers, P.R.H.J. (Western General Hospital) ;
Trompet, S. (Leiden University Medical Center) ;
Turman, C. (Chan School of Public Health) ;
Vaccargiu, S. (Consiglio Nazionale delle Ricerche) ;
van der Laan, S.W. (Utrecht University) ;
van der Most, P.J. (University Medical Center Groningen) ;
van Klinken, J.B. (University of Amsterdam) ;
van Setten, J. (Utrecht University) ;
Verma, S.S. (University of Pennsylvania) ;
Verweij, N. (University Medical Center Groningen) ;
Veturi, Y. (University of Pennsylvania) ;
Wang, C.A. (The University of Newcastle) ;
Wang, C. (Huazhong University of Science and Technology) ;
Wang, L. (Washington University School of Medicine) ;
Wang, Z. (Icahn School of Medicine at Mount Sinai) ;
Warren, H.R. (Queen Mary University of London) ;
Bin Wei, W. (Capital Medical University) ;
Wickremasinghe, A.R. (University of Kelaniya) ;
Wielscher, M. (Medical University of Vienna) ;
Wiggins, K.L. (University of Washington) ;
Winsvold, B.S. (Oslo University Hospital) ;
Wong, A. (University College London) ;
Wu, Y. (The University of Queensland) ;
Wuttke, M. (University of Freiburg) ;
Xia, R. (University of Texas Health Science Center at Houston) ;
Xie, T. (University Medical Center Groningen) ;
Yamamoto, K. (Kurume University School of Medicine) ;
Yang, J. (Westlake Laboratory of Life Sciences and Biomedicine) ;
Yao, J. (Harbor-UCLA Medical Center) ;
Young, H. (University of Minnesota) ;
Yousri, N.A. (Alexandria University) ;
Yu, L. (Rush University Medical Center) ;
Zeng, L. (Technical University Munich) ;
Zhang, W. (Imperial College London) ;
Zhang, X. (University of Pennsylvania) ;
Zhao, J.H. (University of Cambridge) ;
Zhao, W. (University of Michigan School of Public Health) ;
Zhou, W. (Broad Institute of MIT and Harvard) ;
Zimmermann, M.E. (University of Regensburg) ;
Zoledziewska, M. (Consiglio Nazionale delle Ricerche) ;
Adair, L.S. (University of North Carolina at Chapel Hill) ;
Adams, H.H.H. (Universidad Adolfo Ibáñez) ;
Aguilar-Salinas, C.A. (Escuela de Medicina y Ciencias de la Salud) ;
Al-Mulla, F. (Dasman Diabetes Institute) ;
Arnett, D.K. (University of Kentucky) ;
Asselbergs, F.W. (University College London) ;
Åsvold, B.O. (Trondheim University Hospital) ;
Attia, J. (University of Newcastle) ;
Banas, B. (University Hospital Regensburg) ;
Bandinelli, S. (Azienda Toscana Centro) ;
Bennett, D.A. (Rush University Medical Center) ;
Bergler, T. (University Hospital Regensburg) ;
Bharadwaj, D. (Jawaharlal Nehru University) ;
Biino, G. (National Research Council of Italy) ;
Bisgaard, H. (University of Copenhagen) ;
Boerwinkle, E. (University of Texas Health Science Center at Houston) ;
Böger, C.A. (KfH Kidney Center Traunstein) ;
Bønnelykke, K. (University of Copenhagen) ;
Boomsma, D.I. (Vrije Universiteit Amsterdam) ;
Børglum, A.D. (Aarhus University) ;
Borja, J.B. (University of San Carlos) ;
Bouchard, C. (Pennington Biomedical Research Center) ;
Bowden, D.W. (Medical Center Boulevard) ;
Brandslund, I. (University of Southern Denmark) ;
Brumpton, B. (Trondheim University Hospital) ;
Buring, J.E. (Brigham and Women's Hospital) ;
Caulfield, M.J. (Queen Mary University of London) ;
Chambers, J.C. (Imperial College London) ;
Chandak, G.R. (JSS (Deemed to be) University) ;
Chanock, Stephen J. (National Cancer Institute) ;
Chaturvedi, N. (University College London) ;
Chen, Y.D.I. (Harbor-UCLA Medical Center) ;
Chen, Z. (University of Oxford) ;
Cheng, C.Y. (Duke-NUS Medical School) ;
Christophersen, I.E. (Vestre Viken Hospital Trust) ;
Ciullo, M. (IRCCS Neuromed) ;
Cole, J.W. (Baltimore Veterans Affairs Medical Center) ;
Collins, F.S. (National Institutes of Health) ;
Cooper, R.S. (Loyola University Chicago) ;
Cruz, M. (Instituto Mexicano del Seguro Social) ;
Cucca, F. (Università degli Studi di Sassari) ;
Cupples, L.A. (Framingham Heart Study) ;
Cutler, M.J. (Intermountain Medical Center) ;
Damrauer, S.M. (Crescenz VA Medical Center) ;
Dantoft, T.M. (Copenhagen University Hospital - Bispebjerg and Frederiksberg) ;
de Borst, G.J. (University of Utrecht) ;
de Groot, L.C.P.G.M. (Department of Human Nutrition. Wageningen University) ;
De Jager, P.L. (Columbia University Medical Center) ;
de Kleijn, D.P.V. (University of Utrecht) ;
Janaka de Silva, H. (University of Kelaniya) ;
Dedoussis, G.V. (Harokopio University of Athens) ;
den Hollander, A.I. (Radboud University Nijmegen Medical Center) ;
Du, S. (University of North Carolina at Chapel Hill) ;
Easton, D.F. (Department of Oncology. University of Cambridge) ;
Elders, P.J.M. (Amsterdam UMC) ;
Eliassen, A.H. (Chan School of Public Health) ;
Ellinor, P.T. (Massachusetts General Hospital) ;
Elmståhl, S. (Lund University) ;
Erdmann, J. (University Heart Center Lübeck) ;
Evans, M.K. (National Institutes of Health) ;
Fatkin, D. (UNSW Sydney) ;
Feenstra, B. (Statens Serum Institut) ;
Feitosa, M.F. (Washington University School of Medicine) ;
Ferrucci, L. (National Institutes of Health) ;
Ford, I. (University of Glasgow) ;
Fornage, M. (University of Texas Health Science Center at Houston) ;
Franke, A. (Christian-Albrechts University of Kiel) ;
Franks, P.W. (Umeå University) ;
Freedman, B.I. (Medical Center Boulevard) ;
Gasparini, P. (University of Trieste) ;
Gieger, C. (German Center for Diabetes Research) ;
Girotto, G. (University of Trieste) ;
Goddard, M.E. (Precincts and Regions) ;
Golightly, Y.M. (University of North Carolina at Chapel Hill) ;
Gonzalez-Villalpando, C. (Centro de Estudios en Diabetes) ;
Gordon-Larsen, P. (University of North Carolina at Chapel Hill) ;
Grallert, H. (German Center for Diabetes Research) ;
Grant, S.F.A. (Children's Hospital of Philadelphia) ;
Grarup, N. (University of Copenhagen) ;
Griffiths, L. (Queensland University of Technology) ;
Gudnason, V. (University of Iceland) ;
Haiman, C. (Keck School of Medicine of USC) ;
Hakonarson, H. (Children's Hospital of Philadelphia) ;
Hansen, T. (University of Copenhagen) ;
Hartman, C.A. (University Medical Center Groningen) ;
Hattersley, A.T. (University of Exeter Medical School) ;
Hayward, C. (University of Edinburgh) ;
Heckbert, S.R. (University of Washington) ;
Heng, C.K. (National University Health System) ;
Hengstenberg, C. (Medical University of Vienna) ;
Hewitt, A.W. (University of Western Australia) ;
Hishigaki, H. (Otsuka Pharmaceutical Co.) ;
Hoyng, C.B. (Radboud University Nijmegen Medical Center) ;
Huang, P.L. (Massachusetts General Hospital) ;
Huang, W. (Shanghai Industrial Technology Institute) ;
Hunt, S.C. (University of Utah) ;
Hveem, K. (Norwegian University of Science and Technology) ;
Hyppönen, E. (South Australian Health and Medical Research Institute) ;
Iacono, W.G. (University of Minnesota) ;
Ichihara, S. (Jichi Medical University School of Medicine) ;
Ikram, M.A. (University Medical Center Rotterdam) ;
Isasi, C.R. (Albert Einstein College of Medicine) ;
Jackson, R.D. (Ohio State University) ;
Jarvelin, M.R. (Brunel University London) ;
Jin, Z.B. (Wenzhou Medical University) ;
Jöckel, K.H. (University Hospital Essen) ;
Joshi, P.K. (University of Edinburgh) ;
Jousilahti, P. (Finnish Institute for Health and Welfare) ;
Jukema, J.W. (Netherlands Heart Institute) ;
Kähönen, M. (Tampere University) ;
Kamatani, Y. (The University of Tokyo) ;
Kang, K.D. (The Catholic University of Korea Incheon St. Mary's Hospital) ;
Kaprio, J. (University of Helsinki) ;
Kardia, S.L.R. (University of Michigan School of Public Health) ;
Karpe, F. (Churchill Hospital) ;
Kato, N. (National Center for Global Health and Medicine) ;
Kee, F. (Queen's University of Belfast) ;
Kessler, T. (German Centre for Cardiovascular Research) ;
Khera, A.V. (Massachusetts General Hospital) ;
Khor, C.C. (Genome Institute of Singapore) ;
Kiemeney, L.A.L.M. (Radboud University Medical Center) ;
Kim, B.J. (National Institute of Health) ;
Kim, E.K. (Saevit Eye Hospital) ;
Kim, H.L. (Ewha Womans University) ;
Kirchhof, P. (Atrial Fibrillation NETwork) ;
Kivimaki, M. (University College London) ;
Koh, W.P. (National University of Singapore) ;
Koistinen, H.A. (Minerva Foundation Institute for Medical Research) ;
Kolovou, G.D. (Metropolitan Hospital) ;
Kooner, J.S. (Imperial College London) ;
Kooperberg, C. (Fred Hutchinson Cancer Research Center) ;
Köttgen, A. (University of Freiburg) ;
Kovacs, P. (University of Leipzig Medical Center) ;
Kraaijeveld, A. (Utrecht University) ;
Kraft, P. (Chan School of Public Health) ;
Krauss, R.M. (University of California) ;
Kumari, M. (University of Essex) ;
Kutalik, Z. (Swiss Institute of Bioinformatics) ;
Laakso, M. (Kuopio University Hospital) ;
Lange, L.A. (University of Colorado at Denver) ;
Langenberg, C. (Charité - Universitätsmedizin Berlin) ;
Launer, L.J. (National Institutes of Health) ;
Le Marchand, L. (University of Hawaii Cancer Center) ;
Lee, H. (Ewha Womans University School of Medicine) ;
Lee, N.R. (University of San Carlos) ;
Lehtimäki, T. (Tampere University) ;
Li, H. (University of Chinese Academy of Sciences) ;
Li, L. (Peking University Center for Public Health) ;
Lieb, W. (Kiel University) ;
Lin, X. (University of Chinese Academy of Sciences) ;
Lind, L. (Uppsala University) ;
Linneberg, A. (University of Copenhagen) ;
Liu, C.T. (Boston University School of Public Health) ;
Liu, J. (Genome Institute of Singapore) ;
Loeffler, M. (University of Leipzig) ;
London, B. (University of Iowa Hospitals and Clinics) ;
Lubitz, S.A. (Massachusetts General Hospital) ;
Lye, S.J. (Sinai Health System) ;
Mackey, D.A. (University of Western Australia) ;
Mägi, R. (University of Tartu) ;
Magnusson, P.K.E. (Karolinska Institutet) ;
Marcus, G.M. (University of California) ;
Vidal, P.M. (University of Lausanne) ;
Martin, N.G. (QIMR Berghofer Medical Research Institute) ;
März, W. (Medical University of Graz) ;
Matsuda, F. (Kyoto University Graduate School of Medicine) ;
McGarrah, R.W. (Duke University School of Medicine) ;
McGue, M. (University of Minnesota) ;
McKnight, A.J. (Queen's University of Belfast) ;
Medland, S.E. (QIMR Berghofer Medical Research Institute) ;
Mellström, D. (University of Gothenburg) ;
Metspalu, A. (University of Tartu) ;
Mitchell, B.D. (Baltimore Veterans Administration Medical Center) ;
Mitchell, P. (University of Sydney) ;
Mook-Kanamori, D.O. (Leiden University Medical Center) ;
Morris, A.D. (University of Edinburgh) ;
Mucci, L.A. (Chan School of Public Health) ;
Munroe, P.B. (Queen Mary University of London) ;
Nalls, M.A. (Data Tecnica International) ;
Nazarian, S. (University of Pennsylvania) ;
Nelson, A.E. (University of North Carolina at Chapel Hill) ;
Neville, M.J. (Churchill Hospital) ;
Newton-Cheh, C. (Massachusetts General Hospital) ;
Nielsen, C.S. (Oslo University Hospital) ;
Nöthen, M.M. (University Hospital Bonn) ;
Ohlsson, C. (Sahlgrenska University Hospital) ;
Oldehinkel, A.J. (University of Groningen) ;
Orozco, L. (Instituto Nacional de Medicina Genómica) ;
Pahkala, K. (University of Turku) ;
Pajukanta, P. (David Geffen School of Medicine at UCLA) ;
Palmer, C.N.A. (University of Dundee) ;
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Pattaro, C. (University of Lübeck) ;
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Pennell, C.E. (University of Newcastle) ;
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Posthuma, D. (Vrije Universiteit Amsterdam) ;
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Schmidt, B. (University Hospital Essen) ;
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Schmidt, R. (Medical University of Graz) ;
Schulze, M.B. (University of Potsdam) ;
Schunkert, H. (Technische Universität München) ;
Scott, L.J. (University of Michigan School of Public Health) ;
Scott, R.J. (University of Newcastle) ;
Sever, P. (Imperial College London) ;
Shiroma, E.J. (National Institutes of Health) ;
Shoemaker, M.B. (Vanderbilt University Medical Center) ;
Shu, X.O. (Vanderbilt University Medical Center) ;
Simonsick, E.M. (National Institutes of Health) ;
Sims, M. (University of Mississippi) ;
Singh, J.R. (Central University of Punjab) ;
Singleton, A. B. (National Institute on Aging) ;
Sinner, M.F. (LMU Munich) ;
Smith, J.G. (Lund University) ;
Snieder, H. (University Medical Center Groningen) ;
Spector, T.D. (King's College London) ;
Stampfer, M.J. (Chan School of Public Health) ;
Stark, K.J. (University of Regensburg) ;
Strachan, D.P. (University of London) ;
't Hart, L.M. (Leiden University Medical Center) ;
Tabara, Y. (Kyoto University Graduate School of Medicine) ;
Tang, H. (Stanford University School of Medicine) ;
Tardif, J.C. (Université de Montréal) ;
Thanaraj, T.A. (Department of Genetics and Bioinformatics) ;
Timpson, N.J. (University of Bristol) ;
Tönjes, A. (University of Leipzig Medical Center) ;
Tremblay, A. (Université Laval) ;
Tuomi, T. (Folkhälsan Research Center) ;
Tuomilehto, J. (King Abdulaziz University) ;
Tusié-Luna, M.T. (Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ;
Uitterlinden, A.G. (University Medical Center Rotterdam) ;
van Dam, R.M. (The George Washington University) ;
van der Harst, P. (University of Groningen) ;
Van der Velde, N. (Amsterdam Public Health) ;
van Duijn, C.M. (University Medical Center Rotterdam) ;
van Schoor, N.M. (Amsterdam UMC) ;
Vitart, V. (University of Edinburgh) ;
Völker, U. (University Medicine Greifswald) ;
Vollenweider, P. (University of Lausanne) ;
Völzke, H. (DZHK (German Centre for Cardiovascular Research)) ;
Wacher-Rodarte, N.H. (Centro Médico Nacional Siglo XXI) ;
Walker, M. (Newcastle University) ;
Wang, Y.X. (Capital Medical University) ;
Wareham, N.J. (University of Cambridge School of Clinical Medicine) ;
Watanabe, R.M. (Keck School of Medicine of USC) ;
Watkins, Hugh (University of Oxford) ;
Weir, D.R. (University of Michigan) ;
Werge, T.M. (University of Copenhagen) ;
Widen, E. (University of Helsinki) ;
Wilkens, Lynne R. (University of Hawaii Cancer Center) ;
Willemsen, Gonneke (Vrije Universiteit Amsterdam) ;
Willett, Walter C. (Chan School of Public Health) ;
Wilson, James F. (Western General Hospital) ;
Wong, Tien-Yin (Duke-NUS Medical School) ;
Woo, Jeong-Taek (Kyung Hee University School of Medicine) ;
Wright, Alan F. (University of Edinburgh) ;
Wu, Jer-Yuarn (China Medical University) ;
Xu, Huichun (University of Maryland School of Medicine) ;
Yajnik, Chittaranjan S. (King Edward Memorial Hospital and Research Centre) ;
Yokota, Mitsuhiro (Kurume University School of Medicine (Kurume, Japó)) ;
Yuan, Jian-Min (University of Pittsburgh) ;
Zeggini, Eleftheria (Technical University of Munich) ;
Zemel, Babette S. (University of Pennsylvania) ;
Zheng, Wei (Vanderbilt University Medical Center) ;
Zhu, Xiaofeng (Case Western Reserve University) ;
Zmuda, Joseph M. (University of Pittsburgh) ;
Zonderman, Alan B. (National Institutes of Health) ;
Zwart, John-Anker (University of Oslo) ;
Croteau-Chonka, Damien (Brigham and Women's Hospital) ;
Vonk, Judith M. (University Medical Center Groningen) ;
Le Marchand, Loic (University of Hawaii Cancer Center) ;
Chasman, Daniel I. (Brigham and Women's Hospital) ;
Cho, Yoon Shin (Hallym University (Chuncheon, Corea del Sud)) ;
Heid, Iris M. (University of Regensburg) ;
McCarthy, Mark I. (Genentech (South San Francisco, Estats Units)) ;
Ng, Maggie C. Y. (Vanderbilt University Medical Center) ;
O'Donnell, Christopher J. (Veterans Affairs Boston Healthcare System) ;
Rivadeneira, Fernando (Erasmus Medical Center Rotterdam) ;
Thorsteinsdottir, Unnur (University of Iceland) ;
Sun, Yan V. (Atlanta VA Health Care System) ;
Tai, E. Shyong (National University Health System (Singapur)) ;
Boehnke, Michael (University of Michigan School of Public Health) ;
Deloukas, Panos (King Abdulaziz University (Jeddah, Aràbia Saudita)) ;
Justice, Anne E. (Department of Population Health Sciences Geisinger (Danville, Estats Units)) ;
Lindgren, Cecilia M. (University of Oxford) ;
Loos, Ruth J. F. (Icahn School of Medicine at Mount Sinai (New York, Estats Units)) ;
Mohlke, Karen L. (University of North Carolina at Chapel Hill) ;
North, Kari E. (University of North Carolina at Chapel Hill) ;
Stefansson, Kari (University of Iceland) ;
Walters, Robin G. (University of Oxford (Oxford, Regne Unit))) ;
Winkler, Thomas W. (University of Regensburg (Regensburg, Alemanya)) ;
Young, Kristin L. (University of North Carolina at Chapel Hill) ;
Loh, Po-Ru (Harvard Medical School (Boston, Estats Units)) ;
Yang, Jian (Westlake Laboratory of Life Sciences and Biomedicine (Hangzhou, Xina)) ;
Esko, Tõnu (University of Tartu) ;
Assimes, Themistocles (Stanford University School of Medicine) ;
Auton, Adam (23andMe (Sunnyvale, Estats Units)) ;
Abecasis, Goncalo R. (University of Michigan School of Public Health) ;
Willer, Cristen J. (University of Michigan) ;
Locke, Adam E. (Washington University School of Medicine) ;
Berndt, Sonja I. (National Cancer Institute (Rocville, Estats Units)) ;
Lettre, Guillaume (Université de Montréal) ;
Frayling, Timothy M. (University of Exeter (Devon, Anglaterra)) ;
Okada, Yukinori (The University of Tokyo) ;
Wood, Andrew R. (University of Exeter) ;
Visscher, PM. (University of Queensland) ;
Hirschhorn, Joel N. (Harvard Medical School (Boston, Estats Units)) ;
Universitat Autònoma de Barcelona
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes. [...]
2022 -  10.1038/s41586-022-05275-y
Nature, Vol. 610 Núm. 7933 (27 2022) , p. 704-712
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19 p, 2.4 MB |
Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
/
Temprano-Sagrera, Gerard (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sitlani, Collen M. (University of Washington) ;
Bone, William P. (University of Pennsylvania) ;
Martín Bórnez, Miguel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Voight, Benjamin F. (University of Pennsylvania Perelman School of Medicine) ;
Morrison, Alanna C. ;
Damrauer, Scott M. ;
de Vries, Paul S. ;
Smith, Nicholas L. ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Dehghan, Abbas ;
Heath, Adam S. ;
Reiner, Alex P. ;
Johnson, Andrew ;
Richmond, Anne ;
Peters, Annette ;
van Hylckama Vlieg, Astrid ;
McKnight, Barbara ;
Psaty, Bruce M. ;
Hayward, Caroline ;
Ward-Caviness, Cavin ;
O'Donnell, Cristopher ;
Chasman, Daniel ;
Strachan, David P. ;
Tregouet, David A. ;
Mook-Kanamori, Dennis ;
Gill, Dipender ;
Thibord, Florian ;
Asselbergs, Folkert W. ;
Leebeek, Frank W. G. ;
Rosendaal, Frits R. ;
Davies, Gail ;
Homuth, Georg ;
Temprano, Gerard ;
Campbell, Harry ;
Taylor, Herman A. ;
Bressler, Jan ;
Huffman, Jennifer E. ;
Rotter, Jerome I. ;
Yao, Jie ;
Wilson, James F. ;
Bis, Joshua C. ;
Hahn, Julie M. ;
Desch, Karl C. ;
Wiggins, Kerri L. ;
Raffield, Laura M. ;
Bielak, Lawrence F. ;
Yanek, Lisa R. ;
Kleber, Marcus E. ;
Mueller, Martina ;
Kavousi, Maryam ;
Mangino, Massimo ;
Liu, Melissa ;
Brown, Michael R. ;
Conomos, Matthew P. ;
Jhun, Min-A. ;
Chen, Ming-Huei ;
de Maat, Moniek P. M. ;
Pankratz, Nathan ;
Smith, Nicholas L. ;
Peyser, Patricia A. ;
Elliot, Paul ;
Wei, Peng ;
Wild, Philipp S. ;
Morange, Pierre E. ;
van der Harst, Pim ;
Yang, Qiong ;
Le, Ngoc-Quynh ;
Marioni, Riccardo ;
Li, Ruifang ;
Damrauer, Scott M. ;
Cox, Simon R. ;
Trompet, Stella ;
Felix, Stephan B. ;
Völker, Uwe ;
Tang, Weihong ;
Koenig, Wolfgang ;
Jukema, J. Wouter ;
Guo, Xiuqing ;
Lindstrom, Sara ;
Wang, Lu ;
Smith, Erin N. ;
Gordon, William ;
van Hylckama Vlieg, Astrid ;
de Andrade, Mariza ;
Brody, Jennifer A. ;
Pattee, Jack W. ;
Haessler, Jeffrey ;
Brumpton, Ben M. ;
Suchon, Pierre ;
Chen, Ming-Huei ;
Turman, Constance ;
Germain, Marine ;
Wiggins, Kerri L. ;
MacDonald, James ;
Braekkan, Sigrid K. ;
Armasu, Sebastian M. ;
Pankratz, Nathan ;
Jackson, Rabecca D. ;
Nielsen, Jonas B. ;
Giulianini, Franco ;
Puurunen, Marja K. ;
Ibrahim, Manal ;
Heckbert, Susan R. ;
Bammler, Theo K. ;
Frazer, Kelly A. ;
McCauley, Bryan M. ;
Taylor, Kent ;
Pankow, James S. ;
Reiner, Alexander P. ;
Gabrielsen, Maiken E. ;
Deleuze, Jean-François ;
O'Donnell, Chris J. ;
Kim, Jihye ;
McKnight, Barbara ;
Kraft, Peter ;
Hansen, John-Bjarne ;
Rosendaal, Frits R. ;
Heit, John A. ;
Psaty, Bruce M. ;
Tang, Weihong ;
Kooperberg, Charles ;
Hveem, Kristian ;
Ridker, Paul M. ;
Morange, Pierre-Emmanuel ;
Johnson, Andrew D. ;
Kabrhel, Christopher ;
Trégouët, David-Alexandre ;
Smith, Nicholas L. ;
Malik, Rainer ;
Chauhan, Ganesh ;
Traylor, Matthew ;
Sargurupremraj, Muralidharan ;
Okada, Yukinori ;
Mishra, Aniket ;
Rutten-Jacobs, Loes ;
Giese, Anne-Katrin ;
van der Laan, Sander W. ;
Gretarsdottir, Solveig ;
Anderson, Christopher D. ;
Chong, Michael ;
Adams, Hieab HH. ;
Ago, Tetsuro ;
Almgren, Peter ;
Amouyel, Philippe (Institut Pasteur de Lille) ;
Ay, Hakan ;
Bartz, Traci M. ;
Benavente, Oscar R. ;
Bevan, Steve ;
Boncoraglio, Giorgio B. ;
Brown, Robert D. ;
Butterworth, Aadam S. ;
Carrera, Caty ;
Carty, Cara L. ;
Chen, Wei-Min ;
Cole, John W. ;
Correa, Adolfo ;
Cotlarciuc, Ioanna ;
Cruchaga, Carlos ;
Danesh, John ;
de Bakker, Paul I. W. ;
DeStefano, Anita L. ;
den Hoed, Marcel ;
Duan, Qing ;
Engelter, Stefan T. ;
Falcone, Guido J. ;
Gottesman, Rebecca F. ;
Grewal, Raji P. ;
Gudnason, Vilmundur ;
Gustafsson, Stefan ;
Haessler, Jeffrey ;
Harris, Tamara B. ;
Hassan, Ahamad ;
Havulinna, Aki S. ;
Heckbert, Susan R. ;
Holliday, Elizabeth G. ;
Howard, George ;
Hsu, Fang-Chi ;
Hyacinth, Hyacinth I. ;
Arfan Ikram, M. ;
Ingelsson, Erik ;
Irvin, Marguerite R. ;
Jian, Xueqiu ;
Jiménez-Conde, Jordi ;
Johnson, Julie A. ;
Jukema, J. Wouter ;
Kanai, Masahiro ;
Keene, Keith L. ;
Kissela, Brett M. ;
Kleindorfer, Dawn O. ;
Kooperberg, Charles ;
Kubo, Michiaki ;
Lange, Leslie A. ;
Langefeld, Carl D. ;
Langenberg, Claudia ;
Launer, Lenore J. ;
Lee, Jin-Moo ;
Lemmens, Robin ;
Leys, Didier ;
Lewis, Cathryn M. ;
Lin, Wei-Yu ;
Lindgren, Arne G. ;
Lorentzen, Erik ;
Magnusson, Patrik K. ;
Maguire, Jane ;
Manichaikul, Ani ;
McArdle, Patrick F. ;
Meschia, James F. ;
Mitchell, Braxton D. ;
Mosley, Thomas H. ;
Nalls, Michael A. ;
Ninomiya, Toshiharu ;
O'Donnell, Martin J. ;
Psaty, Bruce M. ;
Pulit, Sara L. ;
Rannikmäe, Kristiina ;
Reiner, Alexander P. ;
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Rice, Kenneth ;
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Ridker, Paul M. ;
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Sapkota, Bishwa R. ;
Schmidt, Reinhold ;
Schmidt, Carsten O. ;
Schminke, Ulf ;
Sharma, Pankaj ;
Slowik, Agnieszka ;
Sudlow, Cathie L. M. ;
Tanislav, Christian ;
Tatlisumak, Turgut ;
Taylor, Kent D. ;
Thijs, Vincent N. S. ;
Thorleifsson, Gudmar ;
Thorsteinsdottir, Unnur ;
Tiedt, Steffen ;
Trompet, Stella ;
Tzourio, Christophe ;
van Duijn, Cornelia M. ;
Walters, Matthew ;
Wareham, Nicholas J. ;
Wassertheil-Smoller, Sylvia ;
Wilson, James G. ;
Wiggins, Kerri L. ;
Yang, Qiong ;
Yusuf, Salim ;
Amin, Najaf ;
Aparicio, Hugo S. ;
Arnett, Donna K. ;
Attia, John ;
Beiser, Alexa S. ;
Berr, Claudine ;
Buring, Julie E. ;
Bustamante, Mariana ;
Caso, Valeria ;
Cheng, Yu-Ching ;
Hoan Choi, Seung ;
Chowhan, Ayesha ;
Cullell, Natalia ;
Dartigues, Jean-François ;
Delavaran, Hossein ;
Delgado, Pilar ;
Dörr, Marcus ;
Engström, Gunnar ;
Ford, Ian ;
Gurpreet, Wander S. ;
Hamsten, Anders ;
Heitsch, Laura ;
Hozawa, Aatsushi ;
Ibanez, Laura ;
Ilinca, Andrea ;
Ingelsson, Martin ;
Iwasaki, Motoki ;
Jackson, Rebecca D. ;
Jood, Katarina ;
Jousilahti, Pekka ;
Kaffashian, Sara ;
Kalra, Lalit ;
Kamouchi, Masahiro ;
Kitazono, Takanari ;
Kjartansson, Olafur ;
Kloss, Manja ;
Koudstaal, Peter J. ;
Krupinski, Jerzy ;
Labovitz, Daniel L. ;
Laurie, Cathy C. ;
Levi, Christhoper R. ;
Li, Linxin ;
Lind, Lars ;
Lindgren, Cecilia M. ;
Lioutas, Vasileios ;
Mei Liu, Yong ;
Lopez, Oscar L. ;
Makoto, Hirata ;
Martinez-Majander, Nicolas ;
Matsuda, Koichi ;
Minegishi, Naoko ;
Montaner, Joan ;
Morris, Andrew P. ;
Muiño, Elena ;
Müller-Nurasyid, Martina ;
Norrving, Bo ;
Ogishima, Soichi ;
Parati, Eugenio A. ;
Reddy Peddareddygari, Leema ;
Pedersen, Nancy L. ;
Pera, Joanna ;
Perola, Markus ;
Pezzini, Alessandro ;
Pileggi, Silvana ;
Rabionet, Raquel ;
Riba-Llena, Iolanda ;
Ribasés, Marta ;
Romero, Jose R. ;
Roquer, Jaume ;
Rudd, Anthony G. ;
Sarin, Antti-Pekka ;
Sarju, Ralhan ;
Sarnowski, Chloe ;
Sasaki, Makoto ;
Satizabal, Claudia L. ;
Satoh, Mamoru ;
Sattar, Naveed ;
Sawada, Norie ;
Sibolt, Gerli ;
Sigurdsson, Ásgeir ;
Smith, Albert ;
Sobue, Kenji ;
Soriano-Tárraga, Carolina ;
Stanne, Tara ;
Colin Stine, O. ;
Stott, David J. ;
Strauch, Konstantin ;
Takai, Takako ;
Tanaka, Hideo ;
Tanno, Kozo ;
Teumer, Alexander ;
Tomppo, Liisa ;
Torres-Aguila, Nuria P. ;
Touze, Emmanuel ;
Tsugane, Shoichiro ;
Uitterlinden, Aandre G. ;
Valdimarsson, Einar M. ;
van der Lee, Sven J. ;
Völzke, Henry ;
Wakai, Kenji ;
Weir, David ;
Williams, Stephen R. ;
Wolfe, Charles D.A. ;
Wong, Quenna ;
Xu, Huichun ;
Yamaji, Taiki ;
Sanghera, Dharambir K. ;
Melander, Olle ;
Jern, Christina ;
Strbian, Daniel ;
Fernandez-Cadenas, Israel ;
Longstreth, W.T. ;
Rolfs, Arndt ;
Hata, Jun ;
Woo, Daniel ;
Rosand, Jonathan ;
Pare, Guillaume ;
Hopewell, Jemma C. ;
Saleheen, Danish ;
Stefansson, Kari ;
Worrall, BradfordB. ;
Kittner, Steven J. ;
Seshadri, Sudha ;
Fornage, Myriam ;
Markus, Hugh S. ;
Howson, Joana M. M. ;
Kamatani, Yoichiro ;
Debette, Stephanie ;
Dichgans, Martin ;
Universitat Autònoma de Barcelona
Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively analyze the shared genetic effects within different hemostatic traits, and between these and their associated disease outcomes. [...]
2022 - 10.1111/jth.15698
Journal of Thrombosis and Haemostasis, Vol. 20 Núm. 6 (01 2022) , p. 1331-1349
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9 p, 567.9 KB |
Multimorbidity patterns of chronic conditions and geriatric syndromes in older patients from the MoPIM multicentre cohort study
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Baré i Mañas, Marisa (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Herranz, Susana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Roso-Llorach, Albert (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Jordana, Rosa (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Violán, Concepció (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Lleal, Marina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Roura-Poch, Pere (Consorci Hospitalari de Vic) ;
Arellano, Marta (Parc de Salut MAR de Barcelona) ;
Estrada, Rafael (Hospital de Galdakao (Usansolo, Biscaia)) ;
Nazco, Gloria Julia (Hospital Universitario de Canarias (La Laguna)) ;
de Jaime, Elisabet (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ferrandez, Olivia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Sala, Maria (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Márquez, Miguel Ángel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona
To estimate the frequency of chronic conditions and geriatric syndromes in older patients admitted to hospital because of an exacerbation of their chronic conditions, and to identify multimorbidity clusters in these patients. [...]
2021 - 10.1136/bmjopen-2021-049334
BMJ open, Vol. 11 (november 2021)
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7 p, 230.8 KB |
A foodborne norovirus outbreak in a nursing home and spread to staff and their household contacts
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Parrón, Ignacio (Sub-Direcció Regional a Barcelona del Departament de Salut) ;
Álvarez, Josep (Sub-Direcció Regional a Barcelona del Departament de Salut) ;
Jané, Mireia (Sub-Direcció General de Vigilància i Resposta a Emergències de Salut Pública) ;
Cornejo-Sánchez, Thais (Hospital Universitari Vall d'Hebron) ;
Razquin, Efrén (Laboratori de l'Agència de Salut Pública de Barcelona) ;
Guix, Susana (Universitat de Barcelona) ;
Camps, G. (Sub-Direcció Regional a Barcelona del Departament de Salut) ;
Pérez, Cristina (Sub-Direcció Regional a Barcelona del Departament de Salut) ;
Domínguez, Ángela (Universitat de Barcelona) ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
De Andrés, Anna (Institut d'Investigació Biomèdica Sant Pau) ;
Forns, Maria Lluïsa (Institut d'Investigació Biomèdica Sant Pau) ;
Rius i Gibert, Maria Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
On 16 March 2018, a nursing home notified a possible acute gastroenteritis outbreak that affected 11 people. Descriptive and case-control studies and analysis of clinical and environmental samples were carried out to determine the characteristics of the outbreak, its aetiology, the transmission mechanism and the causal food. [...]
2019 - 10.1017/S0950268819001146
Epidemiology and Infection, Vol. 147 (2019) , p. e225
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9 p, 1.3 MB |
The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function
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Bennett, J.A. (University of Rochester Medical Center) ;
Mastrangelo, M.A. (University of Rochester Medical Center) ;
Ture, S.K. (University of Rochester Medical Center) ;
Smith, C.O. (University of Rochester Medical Center) ;
Loelius, S.G. (University of Rochester Medical Center) ;
Berg, R.A. (University of Rochester Medical Center) ;
Shi, X. (Beth Israel Deaconess Medical Center) ;
Burke, R.M. (University of Rochester Medical Center) ;
Spinelli, S.L. (University of Rochester Medical Center) ;
Cameron, S.J. (University of Rochester Medical Center) ;
Carey, T.E. (University of Michigan) ;
Brookes, Paul S (University of Rochester Medical Center) ;
Gerszten, R.E. (Beth Israel Deaconess Medical Center) ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
de Vries, P.S. (The University of Texas Health Science Center at Houston) ;
Huffman, Jennifer E (VA Boston Healthcare System) ;
Smith, N.L. (Seattle Epidemiologic Research and Information Center) ;
Morrell, C.N. (University of Rochester Medical Center) ;
Lowenstein, C.J. (University of Rochester Medical Center) ;
Universitat Autònoma de Barcelona
Genetic factors contribute to the risk of thrombotic diseases. Recent genome wide association studies have identified genetic loci including SLC44A2 which may regulate thrombosis. Here we show that Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial energetics. [...]
2020 - 10.1038/s41467-020-17254-w
Nature communications, Vol. 11 Núm. 1 (january 2020) , p. 3479
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6.
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13 p, 2.5 MB |
Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk
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López, Sonia (Institut d'Investigació Biomèdica Sant Pau) ;
Martinez-Perez, Angel (Institut d'Investigació Biomèdica Sant Pau) ;
Rodriguez-Rius, Alba (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Viñuela, Ana (Biosciences Institute. Faculty of Medicine. Newcastle University) ;
Brown, Andrew A. (Population Health and Genomics. University of Dundee) ;
Martin-Fernandez, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilalta, Noelia (Institut d'Investigació Biomèdica Sant Pau) ;
Arús, Marc (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Panousis, Nikolaos I. (Department of Genetic Medicine and Development. University of Geneva) ;
Buil, Alfonso (Institute of Biological Psychiatry. Mental Health Sct. Hans Hospital) ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Souto, Juan Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Dermitzakis, Emmanouil T (University of Geneva Medical School) ;
Soria Fernández, José Manuel (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Plasma cell-free DNA (cfDNA) is a surrogate marker of neutrophil extracellular traps (NETs) that contribute to immunothrombosis. There is growing interest about the mechanisms underlying NET formation and elevated cfDNA, but little is known about the factors involved. [...]
2022 - 10.1055/s-0041-1742169
Thrombosis and Haemostasis, Vol. 122 Núm. 6 (january 2022) , p. 1027-1039
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7.
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16 p, 1.1 MB |
Multimorbidity patterns in COVID-19 patients and their relationship with infection severity : MRisk-COVID study
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Lleal, Marina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Corral-Vazquez, Celia (Instituto de Salud Carlos III) ;
Bare Mañas, Montserrat (Institut Català de la Salut) ;
Comet Monte, Ricard (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Herranz, Susana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Baigorri, Francisco (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Gimeno-Miguel, Antonio (Instituto de Salud Carlos III) ;
Raurich, Maria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Fortià, Cristina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Navarro, Marta (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Poblador-Plou, Beatriz (Instituto de Salud Carlos III) ;
Baré i Mañas, Marisa (Instituto de Salud Carlos III) ;
Universitat Autònoma de Barcelona
Several chronic conditions have been identified as risk factors for severe COVID-19 infection, yet the implications of multimorbidity need to be explored. The objective of this study was to establish multimorbidity clusters from a cohort of COVID-19 patients and assess their relationship with infection severity/mortality. [...]
2023 - 10.1371/journal.pone.0290969
PloS one, Vol. 18 (august 2023)
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8.
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42 p, 2.1 MB |
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
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Kanoni, Stavroula (Queen Mary University of London) ;
Graham, Sarah E. (University of Michigan) ;
Wang, Yuxuan (Boston University School of Public Health) ;
Surakka, Ida (University of Michigan) ;
Ramdas, Shweta (University of Pennsylvania) ;
Zhu, Xiang (Stanford University) ;
Clarke, Shoa L. (Stanford University School of Medicine) ;
Bhatti, Konain Fatima (Queen Mary University of London) ;
Vedantam, Sailaja (Broad Institute of MIT and Harvard) ;
Winkler, Thomas W. (University of Regensburg) ;
Locke, Adam E. (Washington University) ;
Marouli, Eirini (Queen Mary University of London) ;
Zajac, Greg J. M. (University of Michigan) ;
Wu, Kuan-Han H. (University of Michigan) ;
Ntalla, Ioanna (Queen Mary University of London) ;
Hui, Qin (Atlanta VA Health Care System) ;
Klarin, Derek (Stanford University School of Medicine) ;
Hilliard, Austin T. (VA Palo Alto Health Care Systems) ;
Wang, Zeyuan (Atlanta VA Health Care System) ;
Xue, Chao (University of Michigan) ;
Thorleifsson, Gudmar (deCODE Genetics/Amgen) ;
Helgadottir, Anna (deCODE Genetics/Amgen) ;
Gudbjartsson, Daniel F. (University of Iceland) ;
Holm, Hilma (deCODE Genetics/Amgen) ;
Olafsson, Isleifur (Landspitali - National University Hospital of Iceland) ;
Hwang, Mi Yeong (National Institute of Health) ;
Han, Sohee (National Institute of Health) ;
Akiyama, Masato (Kyushu University) ;
Sakaue, Saori (The University of Tokyo) ;
Terao, Chikashi (RIKEN Center for Integrative Medical Sciences) ;
Kanai, Masahiro (Harvard Medical School) ;
Zhou, Wei (Massachusetts General Hospital) ;
Brumpton, Ben M. (St Olav's University Hospital) ;
Rasheed, Humaira (University of Oslo) ;
Havulinna, Aki S. (Finnish Institute for Health and Welfare) ;
Veturi, Yogasudha (University of Pennsylvania) ;
Pacheco, Jennifer Allen (Northwestern University) ;
Rosenthal, Elisabeth A. (University of Washington) ;
Lingren, Todd (Cincinnati Children's Hospital Medical Center) ;
Feng, QiPing (Vanderbilt University Medical Center) ;
Kullo, Iftikhar J. (Mayo Clinic) ;
Narita, Akira (Tohoku Medical Megabank Organization) ;
Takayama, Jun (Tohoku Medical Megabank Organization) ;
Martin, Hilary C. (Wellcome Trust Sanger Institute (Regne Unit)) ;
Hunt, Karen A. (Queen Mary University of London) ;
Trivedi, Bhavi (Queen Mary University of London) ;
Haessler, Jeffrey (Fred Hutchinson Cancer Center) ;
Giulianini, Franco (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Bradford, Yuki (University of Pennsylvania) ;
Miller, Jason E. (University of Pennsylvania) ;
Campbell, Archie (University of Edinburgh) ;
Lin, Kuang (University of Oxford) ;
Millwood, Iona Y. (University of Oxford) ;
Rasheed, Asif (Center for Non-Communicable Diseases) ;
Hindy, George (Qatar University College of Medicine) ;
Faul, Jessica D. (University of Michigan) ;
Zhao, Wei (University of Michigan) ;
Weir, David R. (University of Michigan) ;
Turman, Constance (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Huang, Hongyan (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Graff, Mariaelisa (University of North Carolina) ;
Choudhury, Ananyo (University of the Witwatersrand) ;
Sengupta, Dhriti (University of the Witwatersrand) ;
Mahajan, Anubha (University of Oxford) ;
Brown, Michael R. (The University of Texas Health Science Center at Houston) ;
Zhang, Weihua (London North West University Healthcare NHS Trust) ;
Yu, Ketian (University of Michigan) ;
Schmidt, Ellen M. (University of Michigan) ;
Pandit, Anita (University of Michigan) ;
Gustafsson, S (Uppsala University) ;
Yin, Xianyong (University of Michigan) ;
Luan, Jian'an (University of Cambridge School of Clinical Medicine) ;
Zhao, Jing-Hua (University of Cambridge) ;
Matsuda, Fumihiko (Kyoto University Graduate School of Medicine) ;
Jang, Hye-Mi (National Institute of Health) ;
Yoon, Kyungheon (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ;
Medina-Gomez, Carolina (University Medical Center Rotterdam) ;
Pitsillides, Achilleas (Boston University School of Public Health) ;
Hottenga, Jouke Jan (Amsterdam Public Health Research Institute) ;
Wood, Andrew R. (University of Exeter Medical School) ;
Ji, Yingji (University of Exeter Medical School) ;
Gao, Zishan (German Research Center for Environmental Health) ;
Haworth, Simon (University of Bristol) ;
Yousri, Noha A. (Alexandria University) ;
Mitchell, Ruth E. (University of Bristol) ;
Chai, Jin Fang (National University of Singapore and National University Health System) ;
Aadahl, Mette (University of Copenhagen) ;
Bjerregaard, Anne A. (Bispebjerg and Frederiksberg Hospital) ;
Yao, Jie (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ;
Manichaikul, Ani (University of Virginia) ;
Hwu, Chii-Min (Taipei Veterans General Hospital) ;
Hung, Yi-Jen (National Defense Medical Center) ;
Warren, Helen R. (Queen Mary University of London) ;
Ramirez, Julia (Universidad de Zaragoza) ;
Bork-Jensen, Jette (University of Copenhagen) ;
Kårhus, Line L. (Bispebjerg and Frederiksberg Hospital) ;
Goel, Anuj (University of Oxford) ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Noordam, Raymond (Leiden University Medical Center) ;
Mauro, Pala (Consiglio Nazionale Delle Ricerche) ;
Matteo, Floris (Università Degli Studi Di Sassari) ;
McDaid, Aaron F. (Swiss Institute of Bioinformatics) ;
Marques-Vidal, Pedro (Lausanne University Hospital) ;
Wielscher, Matthias (Imperial College London) ;
Trompet, Stella (Leiden University Medical Center) ;
Sattar, Naveed (BHF Glasgow Cardiovascular Research Centre) ;
Møllehave, Line T. (Bispebjerg and Frederiksberg Hospital) ;
Munz, Matthias (University of Lübeck) ;
Zeng, Lingyao (Partner Site Munich Heart Alliance) ;
Huang, Jianfeng (Fuwai Hospital) ;
Yang, Bin (Fuwai Hospital) ;
Poveda, Alaitz (Lund University Diabetes Center) ;
Kurbasic, Azra (Lund University Diabetes Center) ;
Lamina, Claudia (German Chronic Kidney Disease Study) ;
Forer, Lukas (German Chronic Kidney Disease Study) ;
Scholz, Markus (University of Leipzig) ;
Galesloot, Tessel E. (Radboud University Medical Center) ;
Bradfield, Jonathan Paul (Quantinuum Research LLC) ;
Ruotsalainen, Sanni E. (University of Helsinki) ;
Daw, E. Warwick (Washington University School of Medicine) ;
Zmuda, Joseph M. (University of Pittsburgh) ;
Mitchell, Jonathan S. (Affiliated Institute of the University of Lübeck) ;
Fuchsberger, Christian (Affiliated Institute of the University of Lübeck) ;
Christensen, Henry (Lillebaelt Hospital) ;
Brody, Jennifer A. (University of Washington) ;
Vazquez-Moreno, Miguel (Centro Medico Nacional Siglo XXI) ;
Feitosa, Mary F. (Washington University School of Medicine) ;
Wojczynski, Mary K. (Washington University School of Medicine) ;
Wang, Zhe (The Charles Bronfman Institute for Personalized Medicine) ;
Preuss, Michael H. (The Charles Bronfman Institute for Personalized Medicine) ;
Mangino, Massimo (NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust) ;
Christofidou, Paraskevi (King's College London) ;
Verweij, Niek (University of Groningen) ;
Benjamins, Jan W. (University of Groningen) ;
Engmann, Jorgen (University College London) ;
Tsao, Noah L. (University of Pennsylvania) ;
Verma, Anurag (University of Pennsylvania) ;
Slieker, Roderick C. (Leiden University Medical Center) ;
Lo, Ken Sin (Montreal Université de Montréal) ;
Zilhao, Nuno R. (Icelandic Heart Association) ;
Le, Phuong (University of Toronto at Mississauga) ;
Kleber, Marcus E. (SYNLAB MVZ Humangenetik Mannheim GmbH) ;
Delgado, Graciela E. (Heidelberg University) ;
Huo, Shaofeng (University of Chinese Academy of Sciences) ;
Ikeda, Daisuke D. (Tokushima Research Institute) ;
Iha, Hiroyuki (Tokushima Research Institute) ;
Yang, Jian (The University of Queensland) ;
Liu, Jun (University Medical Center Rotterdam) ;
Demirkan, Ayşe (University of Surrey) ;
Leonard, Hampton L. (Data Tecnica International) ;
Marten, Jonathan (University of Edinburgh) ;
Frank, Mirjam (University of Duisburg-Essen) ;
Schmidt, Börge (University of Duisburg-Essen) ;
Smyth, Laura J. (Queen's University of Belfast) ;
Cañadas-Garre, Marisa (Instituto de Investigación Biosanitaria de Granada) ;
Wang, Chaolong (Genome Institute of Singapore) ;
Nakatochi, Masahiro (Nagoya University Graduate School of Medicine) ;
Wong, Andrew (MRC Unit for Lifelong Health and Ageing at UCL) ;
Hutri-Kähönen, Nina (Tampere University) ;
Sim, Xueling (National University of Singapore and National University Health System) ;
Xia, Rui (University of Texas Health Science Center at Houston) ;
Huerta-Chagoya, Alicia (Instituto de Investigaciones Biomédicas (Mèxic)) ;
Fernandez-Lopez, Juan Carlos (Instituto Nacional de Medicina Genómica) ;
Lyssenko, Valeriya (University of Bergen) ;
Nongmaithem, Suraj S. (Academy of Scientific and Innovative Research (AcSIR)) ;
Bayyana, Swati (Academy of Scientific and Innovative Research (AcSIR)) ;
Stringham, Heather M. (University of Michigan.) ;
Irvin, Marguerite R. (University of Alabama at Birmingham) ;
Oldmeadow, Christopher (Hunter Medical Research Institute) ;
Kim, Han-Na (SAIHST, Sungkyunkwan University) ;
Ryu, Seungho (Kangbuk Samsung Hospital) ;
Timmers, Paul R. H. J. (University of Edinburgh) ;
Arbeeva, Liubov (University of North Carolina) ;
Dorajoo, Rajkumar (Duke-NUS Medical School) ;
Lange, Leslie A. (University of Colorado) ;
Prasad, Gauri (CSIR-Human Resource Development Centre) ;
Lorés-Motta, Laura (Radboud University Nijmegen Medical Center) ;
Pauper, Marc (Radboud University Nijmegen Medical Center) ;
Long, Jirong (Vanderbilt University Medical Center) ;
Li, Xiaohui (Harbor-UCLA Medical Center) ;
Theusch, Elizabeth (University of California San Francisco) ;
Takeuchi, Fumihiko (National Center for Global Health and Medicine) ;
Spracklen, Cassandra N. (University of Massachusetts-Amherst) ;
Loukola, Anu (University of Helsinki) ;
Bollepalli, Sailalitha (University of Helsinki) ;
Warner, Sophie C. (Glenfield Hospital) ;
Wang, Ya Xing (Beijing Institute of Ophthalmology) ;
Wei, Wen B. (Beijing Tongren Eye Center) ;
Nutile, Teresa (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" - CNR) ;
Ruggiero, Daniela (IRCCS Neuromed) ;
Sung, Yun Ju (Washington University) ;
Chen, Shufeng (Fuwai Hospital) ;
Liu, Fangchao (Fuwai Hospital) ;
Yang, Jingyun (Rush University Medical Center) ;
Kentistou, Katherine A. (University of Edinburgh) ;
Banas, Bernhard (University Hospital Regensburg) ;
Nardone, Giuseppe Giovanni (IRCCS Burlo Garofolo) ;
Meidtner, Karina (German Center for Diabetes Research (DZD)) ;
Bielak, Lawrence F. (University of Michigan) ;
Smith, Jennifer A. (University of Michigan) ;
Hebbar, Prashantha (Dasman Diabetes Institute) ;
Farmaki, Aliki-Eleni (University College London) ;
Hofer, Edith (Medical University of Graz) ;
Lin, Maoxuan (Massachusetts General Hospital Cancer Center) ;
Concas, Maria Pina (IRCCS Burlo Garofolo) ;
Vaccargiu, Simona (Institute of Genetic and Biomedical Research) ;
van der Most, Peter J (University of Groningen) ;
Pitkänen, Niina (University of Turku and Turku University Hospital) ;
Cade, Brian E. (Harvard Medical School) ;
van der Laan, Sander W (University Medical Center Utrecht) ;
Chitrala, Kumaraswamy Naidu (University of Houston-Sugarland) ;
Weiss, Stefan (University of Greifswald and University Medicine Greifswald) ;
Bentley, Amy R. (National Human Genome Research Institute) ;
Doumatey, Ayo P. (National Human Genome Research Institute) ;
Adeyemo, Adebowale A. (National Human Genome Research Institute) ;
Lee, Jong Young (Soonchunhyang Mirai Medical Center 173) ;
Petersen, Eva R. B. (Hospital of Southern Jutlandy and Immunology) ;
Nielsen, Aneta A. (Lillebaelt Hospital) ;
Choi, Hyeok Sun (Hallym University) ;
Nethander, Maria (University of Gothenburg) ;
Freitag-Wolf, Sandra (Kiel University) ;
Southam, Lorraine (Institute of Translational Genomics) ;
Rayner, Nigel W. (University of Oxford) ;
Wang, Carol A (University of Newcastle) ;
Lin, Shih-Yi (National Defense Medical Center) ;
Wang, Jun-Sing (National Yang Ming Chiao Tung University) ;
Couture, Christian (Université Laval) ;
Lyytikäinen, Leo-Pekka (Finnish Cardiovascular Research Center - Tampere) ;
Nikus, Kjell (Finnish Cardiovascular Research Center - Tampere) ;
Cuellar-Partida, Gabriel (University of Queensland Diamantina Institute) ;
Vestergaard, Henrik (Bornholms Hospital) ;
Hidalgo, Bertha (University of Alabama at Birmingham) ;
Giannakopoulou, Olga (Queen Mary University of London) ;
Cai, Qiuyin (Vanderbilt University Medical Center) ;
Obura, Morgan O. (Amsterdam Public Health Research Institute) ;
van Setten, Jessica (University Medical Center Utrecht) ;
Li, Xiaoyin (Case Western Reserve University) ;
Liang, Jingjing (Case Western Reserve University) ;
Tang, Hua (Stanford University School of Medicine Stanford) ;
Terzikhan, Natalie (University Medical Center Rotterdam) ;
Shin, Jae Hun (Hallym University) ;
Jackson, Rebecca D. (Ohio State University) ;
Reiner, Alexander P. (University of Washington) ;
Martin, Lisa Warsinger (George Washington University) ;
Chen, Zhengming (University of Oxford) ;
Li, Liming (Peking University Health Science Center) ;
Kawaguchi, Takahisa (Kyoto University Graduate School of Medicine) ;
Thiery, Joachim (University Hospital Leipzig) ;
Bis, Joshua C (University of Washington) ;
Launer, Lenore J. (National Institute On Aging) ;
Li, Huaixing (University of Chinese Academy of Sciences) ;
Nalls, Mike A. (Data Tecnica International) ;
Raitakari, Olli T. (Turku University Hospital (Finlàndia)) ;
Ichihara, Sahoko (Jichi Medical University School of Medicine) ;
Wild, Sarah H. (University of Edinburgh) ;
Nelson, Christopher P. (NIHR Leicester Biomedical Research Centre) ;
Campbell, Harry (University of Edinburgh) ;
Jäger, Susanne (German Center for Diabetes Research (DZD)) ;
Nabika, Toru (Shimane University School of Medicine) ;
Al-Mulla, Fahd (Dasman Diabetes Institute) ;
Niinikoski, Harri (University of Turku) ;
Braund, Peter S. (NIHR Leicester Biomedical Research Centre) ;
Kolcic, Ivana (University of Split School of Medicine) ;
Kovacs, Peter (University of Leipzig Medical Center) ;
Giardoglou, Tota (Harokopio University) ;
Katsuya, Tomohiro (Osaka University Graduate School of Medicine) ;
de Kleijn, Dominique (University Medical Center Utrecht) ;
de Borst, Gert J. (University Medical Center Utrecht) ;
Kim, Eung Kweon (Yonsei University College of Medicine) ;
Adams, Hieab H. H. (Universidad Adolfo Ibáñez) ;
Ikram, M. Arfan (University Medical Center Rotterdam) ;
Zhu, X (Case Western Reserve University) ;
Asselbergs, Folkert W. (University Medical Center Utrecht) ;
Kraaijeveld, Adriaan O. (University Medical Center Utrecht) ;
Beulens, Joline W. J. (University Medical Centre Utrecht) ;
Shu, Xiao-Ou (Vanderbilt University Medical Center) ;
Rallidis, Loukianos S. (National and Kapodistrian University of Athens) ;
Pedersen, Oluf (University of Copenhagen) ;
Hansen, Torben (University of Copenhagen) ;
Mitchell, Paul (University of Sydney) ;
Hewitt, Alex W. (University of Melbourne) ;
Kähönen, Mika (Tampere University) ;
Pérusse, Louis (Institute of Nutrition and Functional Foods (INAF)) ;
Bouchard, Claude (Pennington Biomedical Research Center) ;
Tönjes, Anke (University of Leipzig Medical Center) ;
Chen, Yii Der Ida (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ;
Pennell, Craig E. (University of Newcastle) ;
Mori, Trevor A. (The University of Western Australia) ;
Lieb, Wolfgang (Kiel University) ;
Franke, Andre (Kiel University) ;
Ohlsson, Claes (Sahlgrenska University Hospital (Suècia)) ;
Mellström, Dan (University of Gothenburg) ;
Cho, Yoon Shin (Hallym University) ;
Lee, Hyejin (EwhaWomans University School of Medicine) ;
Yuan, Jian-Min (University of Pittsburgh) ;
Koh, Woon-Puay (Singapore Institute for Clinical Sciences) ;
Rhee, Sang Youl (Kyung Hee University School of Medicine) ;
Woo, Jeong-Taek (Kyung Hee University School of Medicine) ;
Heid, Iris M. (University of Regensburg) ;
Stark, Klaus J. (University of Regensburg) ;
Zimmermann, Martina E. (University of Regensburg) ;
Völzke, Henry (University Medicine Greifswald) ;
Homuth, Georg (University of Greifswald and University Medicine Greifswald) ;
Evans, Michele K. (National Institute On Aging Intramural Research Program) ;
Zonderman, Alan B. (National Institute On Aging Intramural Research Program) ;
Polasek, Ozren (Algebra University College) ;
Pasterkamp, Gerard (University Medical Center Utrecht) ;
Hoefer, Imo E. (University Medical Center Utrecht) ;
Redline, Susan (Harvard Medical School) ;
Pahkala, Katja (University of Turku) ;
Oldehinkel, Albertine J. (University of Groningen) ;
Snieder, Harold (University Medical Center Groningen) ;
Biino, Ginevra (National Research Council of Italy) ;
Schmidt, Reinhold (Medical University of Graz) ;
Schmidt, Helena (Medical University of Graz) ;
Bandinelli, Stefania (Local Health Unit Toscana Centro) ;
Dedoussis, George (Harokopio University of Athens) ;
Thanaraj, Thangavel Alphonse (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ;
Kardia, Sharon L. R. (University of Michigan) ;
Peyser, Patricia A. (University of Michigan) ;
Kato, Norihiro (National Center for Global Health and Medicine) ;
Schulze, Matthias B. (University of Potsdam) ;
Girotto, Giorgia (University of Trieste) ;
Böger, Carsten A. (KfH Kidney Center Traunstein) ;
Jung, Bettina (KfH Kidney Center Traunstein) ;
Joshi, Peter K. (University of Edinburgh) ;
Bennett, David A. (Rush University Medical Center) ;
De Jager, Philip L. (Columbia University Medical Center) ;
Lu, Xiangfeng (Fuwai Hospital) ;
Mamakou, Vasiliki (Dromokaiteio Psychiatric Hospital) ;
Brown, Morris (Queen Mary University of London) ;
Caulfield, Mark J. (Queen Mary University of London) ;
Munroe, Patricia B. (Queen Mary University of London) ;
Guo, Xiuqing (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ;
Ciullo, Marina (IRCCS Neuromed) ;
Jonas, Jost B. (Privatpraxis Prof Jonas Und Dr Panda-Jonas) ;
Samani, Nilesh J. (NIHR Leicester Biomedical Research Centre) ;
Kaprio, Jaakko (University of Helsinki) ;
Pajukanta, Päivi (University of California) ;
Tusié-Luna, Teresa (Instituto de Investigaciones Biomédicas UNAM/ Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán) ;
Aguilar-Salinas, Carlos Alberto (Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán) ;
Adair, Linda S. (University of North Carolina) ;
Bechayda, Sonny Augustin (University of San Carlos) ;
de Silva, H. Janaka (University of Kelaniya) ;
Wickremasinghe, Ananda R. (University of Kelaniya) ;
Krauss, Ronald M. (Children's Hospital Oakland Research Institute) ;
Wu, Jer-Yuarn (Institute of Biomedical Sciences) ;
Zheng, Wei (Vanderbilt University Medical Center) ;
Hollander, Anneke Iden (Radboud University Nijmegen Medical Center) ;
Bharadwaj, Dwaipayan (Jawaharlal Nehru University) ;
Correa, Adolfo (University of Mississippi Medical Center) ;
Wilson, James G. (University of Mississippi Medical Center) ;
Lind, Lars (Uppsala University) ;
Heng, Chew-Kiat (Yong Loo Lin School of Medicine) ;
Nelson, Amanda E. (University of North Carolina) ;
Golightly, Yvonne M. (University of North Carolina) ;
Wilson, James F. (University of Edinburgh) ;
Penninx, Brenda (Vrije Universiteit Amsterdam) ;
Kim, Hyung-Lae (Ewha Womans University) ;
Attia, John (University of Newcastle) ;
Scott, Rodney J. (University of Newcastle) ;
Rao, D. C. (Washington University School of Medicine) ;
Arnett, Donna K. (University of South Carolina) ;
Hunt, Steven C. (University of Utah) ;
Walker, Mark (Institute of Cellular Medicine (Diabetes)) ;
Koistinen, Heikki A. (Minerva Foundation Institute for Medical Research) ;
Chandak, Giriraj R. (JSS Academy of Higher Education and Research) ;
Mercader, Josep M. (Harvard Medical School) ;
Costanzo, Maria C. (Broad Institute of MIT and Harvard) ;
Jang, Dongkeun (Broad Institute of MIT and Harvard) ;
Burtt, Noël P. (Broad Institute of MIT and Harvard) ;
Villalpando, Clicerio Gonzalez (InstitutoNacional de Salud Publica Y Centro de Estudios en Diabetes (Mèxic)) ;
Orozco, Lorena (Instituto Nacional de Medicina Genómica) ;
Fornage, Myriam (University of Texas Health Science at Houston) ;
Tai, EShyong (Yong Loo Lin School of Medicine) ;
van Dam, Rob M. (Milken Institute School of Public Health) ;
Lehtimäki, Terho (Finnish Cardiovascular Research Center - Tampere) ;
Chaturvedi, Nish (MRC Unit for Lifelong Health and Ageing at UCL) ;
Yokota, Mitsuhiro (Kurume University School of Medicine) ;
Liu, Jianjun (Genome Institute of Singapore) ;
Reilly, Dermot F. (Merck Sharp & Dohme Corp.. Genetics) ;
McKnight, Amy Jayne (Queen's University of Belfast) ;
Kee, Frank (Queen's University of Belfast) ;
Jöckel, Karl-Heinz (University of Duisburg-Essen) ;
McCarthy, Mark I. (University of Oxford) ;
Palmer, Colin N. A. (University of Dundee) ;
Vitart, Veronique (University of Edinburgh) ;
Hayward, Caroline (University of Edinburgh) ;
Simonsick, Eleanor (National Institute On Aging) ;
van Duijn, Cornelia M. (University Medical Center Rotterdam) ;
Jin, Zi-Bing (Wenzhou Medical University) ;
Qu, Jia (Wenzhou Medical University) ;
Hishigaki, Haretsugu (Tokushima Research Institute) ;
Lin, Xu (University of Chinese Academy of Sciences) ;
März, Winfried (Medical University of Graz) ;
Gudnason, Vilmundur (University of Iceland) ;
Tardif, Jean-Claude (Université de Montréal) ;
Lettre, Guillaume (Université de Montréal) ;
Hart, Leen M.'t (Amsterdam Public Health Research Institute) ;
Elders, Petra J. M. (Amsterdam Public Health Research Institute) ;
Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ;
Kumari, Meena (University of Essex) ;
Kivimaki, Mika (University College London) ;
van der Harst, Pim (Utrecht University) ;
Spector, Tim D. (King's College London) ;
Loos, Ruth J. F. (Icahn School of Medicine at Mount Sinai) ;
Province, Michael A. (Washington University School of Medicine) ;
Parra, Esteban J. (University of Toronto at Mississauga) ;
Cruz, Miguel (Centro Medico Nacional Siglo XXI) ;
Psaty, Bruce M. (University of Washington) ;
Brandslund, Ivan (University of Southern Denmark) ;
Pramstaller, Peter P. (Affiliated Institute of the University of Lübeck) ;
Rotimi, Charles N. (Center for Research On Genomics and Global Health) ;
Christensen, Kaare (University of Southern Denmark) ;
Ripatti, Samuli (Broad Institute of MIT and Harvard) ;
Widén, Elisabeth (University of Helsinki) ;
Hakonarson, Hakon (The University of Pennsylvania Perelman School of Medicine) ;
Grant, Struan F. A. (Children's Hospital of Philadelphia (Pennsilvània)) ;
Kiemeney, Lambertus A. L. M. (Radboud University Medical Center) ;
de Graaf, Jacqueline (Radboud University Medical Center) ;
Loeffler, Markus (University of Leipzig) ;
Kronenberg, Florian (German Chronic Kidney Disease Study (Alemanya)) ;
Gu, Dongfeng (Southern University of Science and Technology) ;
Erdmann, Jeanette (University Heart Center Lübeck) ;
Schunkert, Heribert (Partner Site Munich Heart Alliance) ;
Franks, Paul W. (Lund University Diabetes Centre) ;
Linneberg, Allan (University of Copenhagen) ;
Jukema, J. Wouter (Netherlands Heart Institute) ;
Khera, Amit V. (Verve Therapeutics) ;
Männikkö, Minna (Northern Finland Birth Cohorts) ;
Jarvelin, Marjo-Riitta (University of Oulu) ;
Kutalik, Zoltan (Swiss Institute of Bioinformatics) ;
Francesco, Cucca (University of Sassari) ;
Mook-Kanamori, Dennis O. (Leiden University Medical Center) ;
van Dijk, Ko Willems (Leiden University Medical Center) ;
Watkins, Hugh (University of Oxford) ;
Strachan, David P. (University of London) ;
Grarup, Niels (University of Copenhagen) ;
Sever, Peter (Imperial College London) ;
Poulter, Neil (Imperial College London) ;
Chuang, Lee-Ming (National Taiwan University Hospital (Taipei, Taiwan)) ;
Rotter, Jerome I. (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ;
Dantoft, Thomas M. (Bispebjerg and Frederiksberg Hospital) ;
Karpe, Fredrik (NIHR Oxford Biomedical Research Centre) ;
Neville, Matt J. (NIHR Oxford Biomedical Research Centre) ;
Timpson, Nicholas J. (University of Bristol) ;
Cheng, Ching-Yu (Duke-NUS Medical School) ;
Wong, Tien-Yin (Duke-NUS Medical School) ;
Khor, Chiea Chuen (Genome Institute of Singapore) ;
Li, Hengtong (Singapore Eye Research Institute) ;
Sabanayagam, Charumathi (Duke-NUS Medical School) ;
Peters, Annette (German Center for Diabetes Research (DZD)) ;
Gieger, Christian (German Center for Diabetes Research (DZD)) ;
Hattersley, Andrew T. (University of Exeter) ;
Pedersen, Nancy L. (Karolinska Institutet (Estocolm, Suècia)) ;
Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia)) ;
Boomsma, Dorret I. (Amsterdam Public Health Research Institute) ;
Willemsen, Allegonda H. M. (Amsterdam Public Health Research Institute) ;
Cupples, LAdrienne (US National Institutes of Health) ;
van Meurs, Joyce B. J. (University Medical Center Rotterdam) ;
Ghanbari, Mohsen (Mashhad University of Medical Sciences) ;
Gordon-Larsen, Penny (University of North Carolina) ;
Huang, Wei (Chinese National Human Genome Center at Shanghai) ;
Kim, Young Jin (National Institute of Health) ;
Tabara, Yasuharu (Kyoto University Graduate School of Medicine) ;
Wareham, Nicholas J. (University of Cambridge School of Clinical Medicine) ;
Langenberg, Claudia (Berlin Institute of Health at Charité - Universitätsmedizin) ;
Zeggini, Eleftheria (Helmholtz Zentrum München - German Research Center for Environmental Health) ;
Kuusisto, Johanna (University of Eastern Finland and Kuopio University Hospital) ;
Laakso, Markku (University of Eastern Finland and Kuopio University Hospital) ;
Ingelsson, Erik (Stanford University) ;
Abecasis, Goncalo (Regeneron Pharmaceuticals) ;
Chambers, John C. (Imperial College London) ;
Kooner, Jaspal S. (Imperial College London) ;
de Vries, Paul S. (The University of Texas Health Science Center at Houston) ;
Morrison, Alanna C. (The University of Texas Health Science Center at Houston) ;
Hazelhurst, Scott (University of the Witwatersrand) ;
Ramsay, Michèle (University of the Witwatersrand) ;
North, Kari E. (University of North Carolina) ;
Daviglus, Martha (University of Illinois College of Medicine) ;
Kraft, Peter (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Martin, Nicholas G. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Whitfield, John B. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Abbas, Shahid (Faisalabad Institute of Cardiology) ;
Saleheen, Danish (Columbia University Irving Medical Center) ;
Walters, Robin G. (University of Oxford) ;
Holmes, Michael V. (Oxford University Hospitals) ;
Black, Corri (University of Aberdeen) ;
Smith, Blair H. (University of Dundee) ;
Baras, Aris (Regeneron Pharmaceuticals) ;
Justice, Anne E. (Geisinger Health) ;
Buring, Julie E. (Harvard Medical School) ;
Ridker, Paul M. (Harvard Medical School) ;
Chasman, Daniel I. (Harvard Medical School) ;
Kooperberg, Charles (Fred Hutchinson Cancer Center) ;
Tamiya, Gen (Tohoku University) ;
Yamamoto, Masayuki (Tohoku University) ;
van Heel, David A (Queen Mary University of London) ;
Trembath, Richard C. (King's College London) ;
Wei, Wei-Qi (Vanderbilt University Medical Center) ;
Jarvik, Gail P. (University of Washington) ;
Namjou, Bahram (Cincinnati Children's Hospital Medical Center) ;
Hayes, M. Geoffrey (Northwestern University) ;
Ritchie, Marylyn D. (University of Pennsylvania) ;
Jousilahti, Pekka (Finnish Institute for Health and Welfare) ;
Salomaa, Veikko (Finnish Institute for Health and Welfare) ;
Hveem, Kristian (St Olav's University Hospital) ;
Åsvold, Bjørn Olav (St Olav's University Hospital) ;
Kubo, Michiaki (RIKEN Center for Integrative Medical Sciences) ;
Kamatani, Yoichiro (The University of Tokyo) ;
Okada, Yukinori (The University of Tokyo) ;
Murakami, Yoshinori (The University of Tokyo) ;
Kim, Bong-Jo (National Institute of Health) ;
Thorsteinsdottir, Unnur (University of Iceland) ;
Stefansson, Kari (The University of Manchester) ;
Zhang, Jifeng (University of Michigan) ;
Chen, YEugene (University of Michigan) ;
Ho, Yuk-Lam (VA Boston Healthcare System) ;
Lynch, Julie A. (University of Massachusetts) ;
Rader, Daniel J. (University of Pennsylvania) ;
Tsao, Philip S. (Stanford University School of Medicine) ;
Chang, Kyong-Mi (University of Pennsylvania Perelman School of Medicine) ;
Cho, Kelly (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
O'Donnell, Christopher J. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Gaziano, John M. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Wilson, Peter W. F. (Emory University School of Medicine) ;
Frayling, Timothy M. (University of Exeter Medical School) ;
Hirschhorn, Joel N. (Harvard Medical School) ;
Kathiresan, Sekar (Harvard Medical School) ;
Mohlke, Karen L. (University of North Carolina) ;
Sun, Yan V. (Atlanta VA Health Care System) ;
Morris, Andrew P. (The University of Manchester) ;
Boehnke, Michael (University of Michigan) ;
Brown, Christopher D. (University of Pennsylvania) ;
Natarajan, Pradeep (Massachusetts General Hospital) ;
Deloukas, Panos (King Abdulaziz University) ;
Willer, Cristen J. (University of Michigan) ;
Assimes, Themistocles (Stanford University School of Medicine. Cardiovascular Institute) ;
Peloso, Gina M (Boston University School of Public Health. Department of Biostatistics) ;
Universitat Autònoma de Barcelona
Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery. [...]
2022 - 10.1186/s13059-022-02837-1
Genome biology, Vol. 23 (december 2022)
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9.
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2 p, 298.3 KB |
A predictive model of mortality in acute renal failure in the critical patient : usefulness of artificial intelligence
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Ibeas, Jose (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Lleal, Elia (Universitat Pompeu Fabra) ;
Macias Toro, Edwar Hernando (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Rubiella, Carolina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Morell Pérez, Antoni (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Serrano García, Javier 1964- (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
López Vicario, José (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes)
Background and Aims: Patients with Acute Renal Failure (ARF) have a high risk of mortality, especially those who enter the Intensive Care Unit (ICU). In this population, predictive models of mortality on prognostic scales, such as SAPS-II (Simplified Acute Physiology Score II), linearly relate risk factors without taking into account the complex relationship's variables can have. [...]
2020 - 10.1093/ndt/gfaa139.SO019
Nephrology Dialysis Transplantation, Vol. 35, Issue Supplement_3 (June 2020) , art. gfaa139.SO019
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10.
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15 p, 1.2 MB |
Sex Differences in Multimorbidity, Inappropriate Medication and Adverse Outcomes of Inpatient Care : MoPIM Cohort Study
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Baré i Mañas, Marisa (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Lleal, Marina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Sevilla-Sánchez, Daniel (Parc Sanitari Pere Virgili) ;
Ortonobes, Sara (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Herranz, Susana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ferrández, Olivia (Parc de Salut MAR de Barcelona) ;
Corral-Vázquez, Celia (Instituto de Salud Carlos III) ;
Molist-Brunet, Núria (Consorci Hospitalari de Vic) ;
Nazco, Gloria Julia (Hospital Universitario de Canarias (La Laguna)) ;
Martín-González, Candelaria (Hospital Universitario de Canarias (La Laguna)) ;
Márquez, Miguel Ángel (Parc de Salut MAR de Barcelona) ;
Universitat Autònoma de Barcelona
There is no published evidence on the possible differences in multimorbidity, inappropriate prescribing, and adverse outcomes of care, simultaneously, from a sex perspective in older patients. We aimed to identify those possible differences in patients hospitalized because of a chronic disease exacerbation. [...]
2023 - 10.3390/ijerph20043639
International journal of environmental research and public health, Vol. 20 (february 2023)
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