2026-03-05
16:16 |
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2026-03-12
19:12 |
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18 p, 4.6 MB |
HLA-DRB1 Allelic Combinations Differentially Shape Dendritic Cell Antigen Presentation Enhanced by Tumour Cell Line Lysate-Pulsing
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Lázaro Bermejo, Gonzalo (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Cedano Rodríguez, Juan Antonio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Faus Cid, Maitane (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Roura Mir, Carme (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Garrigós Cubells, Laia (Centre Internacional de Càncer de Mama. Barcelona) ;
Pérez-García, José (Medical Scientia Innovation Research (MedSIR)) ;
Román-García, Javier (Universidad Europea de Madrid) ;
Cortés Castán, Javier (Medical Scientia Innovation Research (MedSIR)) ;
Aran, Andrea (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Martí, Mercè (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
The anti-tumour immune response plays a pivotal role in eliminating tumour cells, with the presence of tumour-infiltrating lymphocytes (TILs) often correlated with improved patient outcomes. Among these, CD4+ T lymphocytes act as key orchestrators of the immune response, functioning as effector and regulatory cells, and are essential for establishing immunological memory. [...]
2026 -  10.1111/tan.70563
HLA: Immune Response Genetics, Vol. 107, Num. 2 (February 2026) , art. e70563
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2026-03-05
08:14 |
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9 p, 3.1 MB |
Biotin-specific molecularly imprinted polymers as a biomimetic test line in lateral flow assays
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Marfà, Jennifer (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Valle, Anaixis del (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Rovatti Pupin, Rafael (Universidade Estadual Paulista "Júlio de Mesquita Filho". Departamento de Química Analítica) ;
Baró Sastre, Barbara (Institut de Salut Global de Barcelona) ;
Bassat, Quique (Hospital Clínic i Provincial de Barcelona) ;
Taboada Sotomayor, Maria Del Pilar (Universidade Estadual Paulista "Júlio de Mesquita Filho". Departamento de Química Analítica) ;
Pividori, María Isabel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Lateral flow assays are widely used for rapid diagnostics at the point of care. However, their dependence on biological receptors limits their stability, scalability, and cost-effectiveness. This work demonstrates the use of biotin-specific molecularly imprinted polymers (biotin-MIPs) as synthetic recognition elements in nucleic acid lateral flow (NALF) assays. [...]
2026 - 10.1016/j.bios.2026.118415
Biosensors & bioelectronics, Vol. 298 (April 2026) , art. 118415
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2026-02-26
19:12 |
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19 p, 3.6 MB |
Preparation of cell-derived vesicles from eukaryotic and prokaryotic origins for the delivery of biomolecules
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Atienza-Garriga, Jan (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Smithers, Luke (The University of Western Australia) ;
Cooper, Crystal (The University of Western Australia) ;
Vrielink, Alice (The University of Western Australia) ;
Ferrer-Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Cell membrane-derived vesicles play essential roles in intercellular communication, material transport, and waste disposal. Despite their biomedical and industrial potential, isolating extracellular vesicles from natural sources remains technically challenging, limiting purification efficiency and scalability. [...]
2026 - 10.1080/21691401.2025.2599072
Artificial Cells, Nanomedicine and Biotechnology, Vol. 54, Num. 1 (January 2026) , p. 1-18
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2026-03-05
08:14 |
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9 p, 3.6 MB |
Competitive magneto enzyme-linked miRNA assay for quantification of microRNAs in exosomes
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Bernuz, Mireia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Martí, Mercè (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
MicroRNAs (miRNAs) are non-coding, short RNA sequences involved in gene regulation. Although intracellular molecules, miRNAs are also found in biological fluids, where they serve as promising diagnostic and prognostic biomarkers. [...]
2026 - 10.1016/j.talanta.2026.129431
Talanta, Vol. 302 (May 2026) , art. 129431
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2026-03-05
08:14 |
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12 p, 3.4 MB |
AGGRESCAN and its evolution : A two-decade perspective on protein aggregation prediction
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Pesce, Giulia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Solé Pozas, Josep Oriol (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Bárcenas, Oriol (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Ventura, Salvador (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Protein aggregation is a widespread phenomenon with profound biological, biomedical, and biotechnological implications. In human disease, aberrant protein self-assembly is a hallmark of numerous neurodegenerative disorders, whereas in the biopharmaceutical industry, aggregation complicates the production, stability, and formulation of therapeutic proteins. [...]
2026 - 10.1007/s12551-025-01404-9
Biophysical Reviews, January 2026
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2026-02-25
18:12 |
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11 p, 8.1 MB |
Subcutaneous administration of an endocrine-mimetic platform allows for prolonged tumor uptake of a tumor targeting protein
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Álamo, Patricia (Institut de Recerca Sant Pau) ;
López-Laguna, Hèctor (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
de Pinho Favaro, Marianna T. (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Gallardo, Alberto (Institut de Recerca Sant Pau) ;
Alba Castellón, Lorena (Institut de Recerca Sant Pau) ;
Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Mangues, Ramon 1957- (Institut de Recerca Sant Pau) ;
Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Endocrine-like dynamic protein depots can be fabricated in vitro through the coordination of divalent zinc ions (Zn) with solvent-exposed histidine residues on functional proteins, leading to their controlled aggregation. [...]
2026 - 10.1016/j.ijpharm.2026.126585
International journal of pharmaceutics, Vol. 690 (February 2026) , art. 126585
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2026-01-28
20:10 |
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14 p, 3.4 MB |
Where do sea turtles forage in the Mediterranean sea? Filling the gaps for a regional assessment of migration routes
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Vela-Garcia, Helena (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Karaman, Sezgin (Hakkari University) ;
Sürücü, Bahattin (Camikebir Mahallesi) ;
Turkozan, Oguz (Aydın Adnan Menderes University) ;
Pascual, Marta (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Pegueroles Queralt, Maria Cinta (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Carreras, Carles (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Universitat Autònoma de Barcelona.
Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Sea turtles are highly migratory species that can travel vast distances between their feeding and breeding sites. Considering the vulnerability and conservation concern of most sea turtle species, it is essential to establish connections between foraging and nesting areas to link threats at seas with the affected populations. [...]
2025 - 10.3389/fmars.2025.1661954
Frontiers in marine science, Vol. 12 (November 2025) , art. 1661954
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2026-01-28
18:13 |
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18 p, 5.6 MB |
De novo genome assembly, inversion detection, and worldwide adaptation on the invasive species Styela plicata
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Galià Camps, Carles (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Schell, Tilman (Senckenberg Forschungsinstitut und Naturmuseum) ;
Pegueroles Queralt, Maria Cinta (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Baranski, Damian (Senckenberg Forschungsinstitut und Naturmuseum) ;
Ben Hamadou, Alexander (Senckenberg Forschungsinstitut und Naturmuseum) ;
Horaud, Mathilde (University of Norway) ;
Antich, Adrià (Centre d'Estudis Avançats de Blanes) ;
Turon, Xavier (Centre d'Estudis Avançats de Blanes) ;
Pascual, Marta (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Greve, Carola (Senckenberg Forschungsinstitut und Naturmuseum) ;
Carreras, Carles (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Universitat Autònoma de Barcelona.
Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Biological invasions are a major threat to biodiversity. However, genomic resources of invasive species are scarce, compromising the study of their invasive success and our ability to mitigate their effects. [...]
2025 - 10.1038/s41598-025-24574-8
Scientific reports, Vol. 15 (November 2025) , art. 40328
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2026-02-02
16:44 |
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