|
1.
|
|
8 p, 1.5 MB |
CD44-negative parietal-epithelial cell staining in minimal change disease : Association with clinical features, response to corticosteroids and kidney outcome
/
Roca, Neus (Universitat de Vic) ;
Jatem, Elias (Hospital Universitari Arnau de Vilanova) ;
Abo, Anabel (Institut de Recerca Biomèdica Dr Pifarré) ;
Santacana, Maria (Institut de Recerca Biomèdica Dr Pifarré) ;
Cruz, Alejandro (Hospital Universitari Vall d'Hebron) ;
Madrid, Álvaro (Hospital Sant Joan de Dèu Barcelona) ;
Fraga Rodríguez, Gloria María (Institut d'Investigació Biomèdica Sant Pau) ;
Martin, Marisa (Hospital Universitari Arnau de Vilanova) ;
Gonzalez, Jorge (Hospital Universitari Arnau de Vilanova) ;
Martinez, Cristina (Institut de Recerca Biomèdica Dr Pifarré) ;
Balius, Anna (Fundació Althaia de Manresa) ;
Segarra, Alfons (Hospital Universitari Arnau de Vilanova) ;
Universitat Autònoma de Barcelona
Activation of parietal-epithelial cells (PECs) with neo-expression of CD44 has been found to play a relevant role in the development of focal and segmental glomerulosclerosis (FSGS). The aim of this study was to analyse whether the expression of CD44 by PECs in biopsies of minimal change disease (MCD) is associated with the response to corticosteroids, with kidney outcomes and/or can be considered an early sign of FSGS. [...]
2022 -  10.1093/ckj/sfab215
Clinical Kidney Journal, Vol. 15 Núm. 3 (january 2022) , p. 545-552
|
|
|
2.
|
|
|
3.
|
|
20 p, 8.2 MB |
Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16 INK4a -deficient epithelial cells
/
Bernal Martínez, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Moltó Abad, Marc (Hospital Universitari Vall d'Hebron) ;
Domínguez, Daniel (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Tusell Padrós, Laura (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Telomere dysfunction drives chromosome instability through endless breakage-fusion-bridge (BFB) cycles that promote the formation of highly rearranged genomes. However, reactivation of telomerase or ALT-pathway is required for genome stabilisation and full malignant transformation. [...]
2018 - 10.18632/oncotarget.25502
Oncotarget, Vol. 9 (june 2018) , p. 27151-27170
|
|
|
4.
|
|
14 p, 2.3 MB |
Delayed γH2AX foci disappearance in mammary epithelial cells from aged women reveals an age-associated DNA repair defect
/
Anglada Pons, Teresa (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Repullés Fernández, Joan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Espinal Berenguer, Anna (Universitat Autònoma de Barcelona. Servei d'Estadística Aplicada) ;
LaBarge, Mark A. (Lawrence Berkeley National Laboratory) ;
Stampfer, Martha R. (Lawrence Berkeley National Laboratory) ;
Genescà, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Martín Flix, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Institut d'Investigació Biomèdica Sant Pau
Aging is a degenerative process in which genome instability plays a crucial role. To gain insight into the link between organismal aging and DNA repair capacity, we analyzed DNA double-strand break (DSB) resolution efficiency in human mammary epithelial cells from 12 healthy donors of young and old ages. [...]
2019 - 10.18632/aging.101849
Aging (Albany NY), Vol. 11, Num. 5 (March 2019) , p. 1510-1523
|
|
|
5.
|
|
18 p, 3.3 MB |
Pivotal role of AKT2 during dynamic phenotypic change of breast cancer stem cells
/
Gener, Petra (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rafael, Diana (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Seras-Franzoso, Joaquin (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pérez Martín, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alamo Pindado, Luis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Casas, Glòria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arango, Diego (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fernández Caparrós, Yolanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Díaz Riascos, Zamira Vanessa. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Abasolo, Ibane. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Schwartz, Simó (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Therapeutic resistance seen in aggressive forms of breast cancer remains challenging for current treatments. More than half of the patients suffer from a disease relapse, most of them with distant metastases. [...]
2019 - 10.3390/cancers11081058
Cancers, Vol. 11 Núm. 8 (august 2019) , p. 1058
|
|
|
6.
|
|
10 p, 1.7 MB |
Membrane reorganization after photochemical internalization to release transferrin-biofunctionalized polystyrene microparticles
/
Mora Espí, Inmaculada (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Barrios, Leonardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Ibáñez, Elena. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Soriano Martín, Jorge. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Nogués, C. (Carme) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Therapeutic drug carriers can drive their cargo to their target cells. However, an obstacle is usually the entrapment of the drug inside the endolysosomal compartment, which physically impedes its actuation by the impossibility of reaching its molecular site of action. [...]
2018 - 10.1038/s41598-018-35913-3
Scientific reports, Vol. 8 (January 2018) , art. 17617
|
|
|
7.
|
|
18 p, 2.1 MB |
The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types
/
Schlinkert, Paul (Paris Lodron-University of Salzburg. Department of Molecular Biology) ;
Casals, Eudald (Institut Català de Nanociència i Nanotecnologia) ;
Boyles, Matthew S. P. (Paris Lodron-University of Salzburg. Department of Molecular Biology) ;
Tischler, Ulrike (Paris Lodron-University of Salzburg. Department of Molecular Biology) ;
Hornig, Eva (Paris Lodron-University of Salzburg. Department of Molecular Biology) ;
Tran Thi Thanh, Ngoc (Institut Català de Nanociència i Nanotecnologia) ;
Zhao, Jiayuan (Institute for Work and Health) ;
Himly, Martin (Paris Lodron-University of Salzburg. Department of Molecular Biology) ;
Riediker, Michael (Institue for Occupational Medicine) ;
Oostingh, G. J. (Salzburg University of Applied Sciences) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Duschl, Albert (Paris Lodron-University of Salzburg. Department of Molecular Biology)
Background: Nanoparticle (NPs) functionalization has been shown to affect their cellular toxicity. To study this, differently functionalized silver (Ag) and gold (Au) NPs were synthesised, characterised and tested using lung epithelial cell systems. [...]
2015 - 10.1186/s12951-014-0062-4
Journal of nanobiotechnology, Vol. 13 (January 2015) , art. 1
|
|
|
8.
|
|
17 p, 2.0 MB |
Limited Interactions between Streptococcus Suis and Haemophilus Parasuis in In Vitro Co-Infection Studies
/
Mathieu-Denoncourt, Annabelle ;
Letendre, Corinne ;
Auger, Jean-Philippe ;
Segura, Mariela ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Lacouture, Sonia ;
Gottschalk, Marcelo
Streptococcus suis and Haemophilus parasuis are normal inhabitants of the porcine upper respiratory tract but are also among the most frequent causes of disease in weaned piglets worldwide, causing inflammatory diseases such as septicemia, meningitis and pneumonia. [...]
2018 - 10.3390/pathogens7010007
Pathogens, Vol. 7 (january 2018)
|
|
|
9.
|
|
23 p, 9.1 MB |
MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells
/
Sánchez-Cid, Lourdes (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Pons, Mònica (Institut de Biologia Molecular de Barcelona) ;
Lozano, Juan José (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Rubio, Nuria (Institut de Química Avançada de Catalunya) ;
Guerra-Rebollo, Marta (Institut de Química Avançada de Catalunya) ;
Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Paris-Coderch, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Segura, Miquel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fueyo, Raquel (Institut de Biologia Molecular de Barcelona) ;
Arguimbau, Judit (Institut de Biologia Molecular de Barcelona) ;
Zodda, Erika (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Bermudo, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Alonso, Immaculada (Hospital Clínic i Provincial de Barcelona) ;
Caparrós, Xavier (Hospital Clínic i Provincial de Barcelona) ;
Cascante, Marta (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Rafii, Arash (Weill Cornell Medical College. Education City (Ar-Rayyan, Qatar)) ;
Kang, Yibin (Princeton University. Department of Molecular Biology) ;
Martínez-Balbás, Marian (Institut de Biologia Molecular de Barcelona) ;
Weiss, Stephen J. (University of Michigan. Life Sciences Institute) ;
Blanco Fernández, Jerónimo (Institut de Química Avançada de Catalunya) ;
Muñoz, Montserrat (Hospital Clínic i Provincial de Barcelona) ;
Fernández, Pedro L. (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut) ;
Thomson, Timothy M. (Institut de Biologia Molecular de Barcelona) ;
Universitat Autònoma de Barcelona
MicroRNAs are critical regulators of gene networks in normal and abnormal biological processes. Focusing on invasive ductal breast cancer (IDC), we have found dysregulated expression in tumor samples of several microRNAs, including the miR-200 family, along progression from primary tumors to distant metastases, further reflected in higher blood levels of miR-200b and miR-7 in IDC patients with regional or distant metastases relative to patients with primary node-negative tumors. [...]
2017 - 10.18632/oncotarget.20698
Oncotarget, Vol. 8, Num. 48 (October 2017) , p. 83384-83406
|
|
|
10.
|
|
12 p, 1.7 MB |
Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
/
Paaske Utheim, Tor (University College of South East Norway) ;
Salvanos, Panagiotis (University of Oslo) ;
Aass Utheim, Øygunn (Oslo University Hospital (Oslo, Noruega)) ;
Ræder, Sten (The Norwegian Dry Eye Clinic) ;
Pasovic, Lara (University of Oslo) ;
Olstad, Ole Kristoffer (Oslo University Hospital (Oslo, Noruega)) ;
Fideliz de la Paz, Maria (Centre d'Oftalmologia Barraquer (Barcelona, Catalunya)) ;
Sehic, Amer (Vestre Viken Hospital Trust) ;
Universitat Autònoma de Barcelona
The aim of the present study was to investigate the molecular mechanisms underlying activation of cell death pathways using genome-wide transcriptional analysis in human limbal epithelial cell (HLEC) cultures following conventional hypothermic storage in Optisol-GS. [...]
2016 - 10.3390/jfb7010004
Journal of Functional Biomaterials, Vol. 7 (february 2016)
|
|
visitant ::
identificació
alerta personal via correu electrònic o subscribiu-vos al 
canal RSS.
