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Timely insights into the COVID-19 pandemic using real-world data
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Roel Herranz, Elena ;
Prieto Alhambra, Daniel, dir. ;
Duarte Salles, Talita, 1985- dir. ;
Bolibar i Ribas, Ignasi, dir.
Tres anys després de la seva aparició, la malaltia del coronavirus 2019 (COVID-19) continua sent una causa destacada de morbiditat i mortalitat en el món. Durant la pandèmia, les dades del món real (en angles, real-world data) han estat extensament utilitzades per omplir mancances de coneixement en el camp de la COVID-19. [...]
Tres años después de su aparición, la enfermedad por coronavirus 2019 (COVID-19) sigue siendo una causa destacada de morbilidad y mortalidad en el mundo. A lo largo de la pandemia, los datos del mundo real (en inglés, real-world data han sido una importante fuente de información para generar evidencia sobre la COVID-19. [...]
Three years after its emergence, the coronavirus disease 2019 (COVID-19) continues to be a major cause of morbidity and mortality worldwide. Throughout the pandemic, real-world data (RWD) have been extensively used to fill evidence gaps in the field of COVID-19. [...]
Universitat Autònoma de Barcelona. Programa de Doctorat en Metodologia de la Recerca Biomèdica i Salut Pública.
2023
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Treatment of Psoriasis Patients with Latent Tuberculosis Using IL-17 and IL-23 Inhibitors : A Retrospective, Multinational, Multicentre Study
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Torres, Tiago (University of Porto, Portugal) ;
Chiricozzi, Andrea (Università Cattolica del Sacro Cuore, Rome, Italy) ;
Puig Sanz, Lluís (Hospital de la Santa Creu i Sant Pau) ;
Lé, Ana Maria (Centro Académico Clínico ICBAS - CHP, Porto, Portugal) ;
Marzano, Angelo Valerio (Università degli Studi di Milano, Italy) ;
Dapavo, Paolo (University of Turin, Italy) ;
Dauden, Esteban (Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa (IIS-IP), Madrid) ;
Carrascosa, Jόse-Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lazaridou, Elizabeth (Aristotle University School of Medicine, Thessaloniki, Greece) ;
Duarte, Gleison (Instituto Bahiano de Imunoterapias-IBIS, Salvador, Brazil) ;
Carvalho, André V. E. (Hospital Moinhos de Vento, Porto Alegre, Brazil) ;
Romiti, Ricardo (University of São Paulo, Brazil) ;
Rompoti, Natalia (University of Athens, 'A. Sygros' Hospital for Skin and Venereal Diseases, Athens, Greece) ;
Teixeira, Laetitia (Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Portugal) ;
Abreu, Miguel (University of Porto, Portugal) ;
Ippoliti, Elena (Università Cattolica del Sacro Cuore, Rome, Italy) ;
Maronese, Carlo Alberto (Università degli Studi di Milano, Italy) ;
Llamas-Velasco, Mar (Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa (IIS-IP)) ;
Vilarrasa-Rull, Eva (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
del Alcázar, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Daponte, Athina-Ioanna (Aristotle University School of Medicine, Thessaloniki, Greece) ;
Papoutsaki, Marina (University of Athens, 'A. Sygros' Hospital for Skin and Venereal Diseases, Athens, Greece) ;
Carugno, Andrea (ASST Papa Giovanni XXIII, Bergamo, Italy) ;
Bellinato, Francesco (University Hospital of Verona, Italy) ;
Gisondi, Paolo (University Hospital of Verona, Italy) ;
Universitat Autònoma de Barcelona. Departament de Medicina
Tuberculosis has a major global impact. Immunocompetent hosts usually control this disease, resulting in an asymptomatic latent tuberculosis infection (LTBI). Because TNF inhibitors increase the risk of tuberculosis reactivation, current guidelines recommend tuberculosis screening before starting any biologic drug, and chemoprophylaxis if LTBI is diagnosed. [...]
2024 -  10.1007/s40257-024-00845-4
American Journal of Clinical Dermatology, Vol. 25, Num. 2 (march 2024) , p. 333-342
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Quantitative Microvascular Change Analysis Using a Semi-Automated Algorithm in Macula-on Rhegmatogenous Retinal Detachment Assessed by Swept-Source Optical Coherence Tomography Angiography
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Díaz Aljaro, Pablo (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Valldeperas, Xavier (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Broc Iturralde, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Romanic Bubalo, Nevena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Díaz-Aljaro, Ignacio (Department of Ophthalmology, Hospital Clínico Universidad de Chile, Santiago 8380456, Chile) ;
Chu, Zhongdi (Department of Bioengineering, University of Washington, Seattle, WA 98195-5061, USA) ;
Wang, Ruikang K. (Department of Bioengineering, University of Washington, Seattle, WA 98195-5061, USA) ;
Zarranz-Ventura, Javier (Department of Ophthalmology, Hospital Clínic de Barcelona, 08036 Barcelona, Spain)
Purpose: The purpose of this study was to objectively evaluate the longitudinal changes observed in the retinal capillaries in eyes with macula-on rhegmatogenous retinal detachment (RRD), assessed with optical coherence tomography angiography (OCTA), and to assess the role of these microvascular measures as potential biomarkers of postoperative visual outcomes. [...]
2024 - 10.3390/diagnostics14070750
Diagnostics, Vol. 14 (april 2024)
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9 p, 1.2 MB |
Methodology for the simulation of the variability of MOSFETs with polycrystalline high-k dielectrics using CAFM input data
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Ruiz, Ana (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica) ;
Couso, Carlos (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica) ;
Seoane, Natalia (Universidade de Santiago de Compostela. Citius) ;
Porti i Pujal, Marc (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica) ;
Garcia-Loureiro, Antonio (Universidade de Santiago de Compostela. Citius) ;
Nafría i Maqueda, Montserrat (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica)
In this work, a simulation methodology, whose inputs are Conductive Atomic Force Microscope (CAFM) experimental data, is proposed to evaluate the impact of nanoscale variability sources related to the polycrystallization of high-k dielectrics (i. [...]
2021 - 10.1109/ACCESS.2021.3090472
IEEE Access, Vol. 9 (2021) , p. 90568-90576
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12 p, 3.5 MB |
Increased brain fractional perfusion in obesity using intravoxel incoherent motion (IVIM) MRI metrics
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Motger Albertí, Anna (Institut d'Investigació Biomèdica de Girona) ;
de la Calle, Elena (Institut d'Investigació Biomèdica de Girona) ;
Giménez, Mònica (Institut d'Investigació Biomèdica de Girona) ;
Blasco, Gerard (Institut d'Investigació Biomèdica de Girona) ;
Biarnés, Carles (Institut d'Investigació Biomèdica de Girona) ;
Arnoriaga-Rodriguez, Maria (Institut d'Investigació Biomèdica de Girona) ;
Puig, Josep (Institut d'Investigació Biomèdica de Girona) ;
Coll-Martínez, Clàudia (Hospital Universitari de Girona Doctor Josep Trueta) ;
Contreras Rodríguez, Oren (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fernández Real, Jose Manuel (Institut d'Investigació Biomèdica de Girona)
Objective: This research seeks to shed light on the associations between brain perfusion, cognitive function, and mental health in individuals with and without obesity. Methods: In this study, we employed the noninvasive intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) technique to examine brain fractional perfusion (FP) in two groups: individuals with obesity (N = 72) and healthy controls (N = 66). [...]
2024 - 10.1002/oby.24001
Obesity, Vol. 32 Núm. 4 (april 2024) , p. 756-767
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10 p, 859.5 KB |
Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks
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Zhang, Y. (University of Oxford) ;
Ghose, U. (University of Oxford) ;
Buckley, N.J. (University of Oxford) ;
Engelborghs, S. (Vrije Universiteit Brussel) ;
Sleegers, K. (University of Antwerp) ;
Frisoni, G.B. (Department of Psychiatry. University of Geneva) ;
Wallin, A. (University of Gothenburg) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Popp, J. (University of Zürich) ;
Martinez-Lage, P. (CITA-Alzheimer Foundation) ;
Legido-Quigley, C. (Steno Diabetes Center) ;
Barkhof, F. (University College London) ;
Zetterberg, H. (Kong Kong Center for Neurodegenerative Diseases) ;
Visser, P.J. (VU University Medical Center) ;
Bertram, L. (University of Oslo) ;
Lovestone, S. (Janssen RD) ;
Nevado-Holgado, Alejo (University of Oxford) ;
Shi, L. (University of Oxford) ;
Universitat Autònoma de Barcelona
Background and objective: Blood-based biomarkers represent a promising approach to help identify early Alzheimer's disease (AD). Previous research has applied traditional machine learning (ML) to analyze plasma omics data and search for potential biomarkers, but the most modern ML methods based on deep learning has however been scarcely explored. [...]
2022 - 10.3389/fnagi.2022.1040001
Frontiers in aging neuroscience, Vol. 14 (29 2022) , p. 1040001
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15 p, 3.0 MB |
Assessing the value contribution of bimekizumab for the treatment of moderate-to-severe psoriasis using a multidisciplinary reflective multi-criteria decision analysis
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Zozaya, Néboa (Universidad de Las Palmas de Gran Canaria) ;
Abdalla, Fernando (Weber (Madrid)) ;
Alfonso Zamora, Santiago (Psoriasis and Psoriatic Arthritis Patient and Family Association) ;
Balea Filgueiras, Jesus (Complejo Hospitalario Universitario de Ferrol) ;
Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Delgado Sánchez, Olga (Hospital Universitari Son Espases)) ;
Dolz Sinisterra, Francisco (Hospital Universitari Doctor Peset (València)) ;
García-Ruiz, Antonio (Instituto de Investigación Biomédica de Málaga) ;
Herranz Pinto, Pedro (Hospital Universitario La Paz (Madrid)) ;
Manfredi, Antonio (Psoriasis and Psoriatic Arthritis Patient and Family Association) ;
Martínez Olmos, José (Escuela Andaluza de Salud Pública (Granada, Andalusia)) ;
Morales de Los Ríos Luna, Paloma (Hospital General Universitario Gregorio Marañón) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Ros Abarca, Sandra (Institut d'Investigació Biomèdica Sant Pau) ;
Hidalgo-Vega, Álvaro (Universidad de Castilla-La Mancha) ;
Universitat Autònoma de Barcelona
Background: Multi-criteria decision analysis (MCDA) was proposed to surmount arbitrary clinical decisions in the field of biological therapies for psoriatic patients. At the same time, MCDA may further highlight the potential of bimekizumab for the treatment of moderate-to-severe psoriasis, compared to placebo, adalimumab, ustekinumab, secukinumab, and even ixekizumab and risankizumab. [...]
2022 - 10.1080/14737167.2022.2063842
Expert Review of Pharmacoeconomics and Outcomes Research, Vol. 22 Núm. 6 (2022) , p. 941-953
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