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1.
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22 p, 4.5 MB |
Machine Learning Models for Predicting Personalized Tacrolimus Stable Dosages in Pediatric Renal Transplant Patients
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Sánchez-Herrero, Sergio (Universitat Oberta de Catalunya. Departament d'Informàtica, Multimèdia i Telecomunicació.) ;
Calvet Liñan, Laura (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Juan, Ángel A (Universitat Politècnica de València. Centre de Recerca en Gestió i Enginyeria de la Producció)
Tacrolimus, characterized by a narrow therapeutic index, significant toxicity, adverse effects, and interindividual variability, necessitates frequent therapeutic drug monitoring and dose adjustments in renal transplant recipients. [...]
2023 -  10.3390/biomedinformatics3040057
BioMedInformatics, Vol. 3, Issue 4 (December 2023) , p. 926-947
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2.
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22 p, 2.5 MB |
A Hybrid Simulation and Reinforcement Learning Algorithm for Enhancing Efficiency in Warehouse Operations
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Leon, Jonas F. (Universitat Oberta de Catalunya. Departament d'Informàtica, Multimèdia i Telecomunicació) ;
Li, Yuda (Universitat Politècnica de València. Research Center on Production Management and Engineering) ;
Martin, Xabier A (Universitat Politècnica de València. Research Center on Production Management and Engineering) ;
Calvet Liñan, Laura (Universitat Autònoma de Barcelona. Departament d'Enginyeria de Sistemes i Telecomunicacions) ;
Panadero, Javier (Universitat Autònoma de Barcelona. Departament d'Arquitectura de Computadors i Sistemes Operatius) ;
Juan, Ángel A (Universitat Politècnica de València. Research Center on Production Management and Engineering)
The use of simulation and reinforcement learning can be viewed as a flexible approach to aid managerial decision-making, particularly in the face of growing complexity in manufacturing and logistic systems. [...]
2023 - 10.3390/a16090408
Algorithms, Vol. 16, Issue 9 (September 2023) , art. 408
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3.
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24 p, 2.7 MB |
A Discrete-Event Simheuristic for Solving a Realistic Storage Location Assignment Problem
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Fuentes Leon, Jonas (Universitat Oberta de Catalunya. Departament d'Informàtica, Multimèdia i Telecomunicació) ;
Li, Yuda (Universitat Politècnica de València. Departament d'Estadística Aplicada i Investigació Operativa) ;
Peyman, Mohammad (Universitat Oberta de Catalunya. Departament d'Informàtica, Multimèdia i Telecomunicació) ;
Calvet Liñan, Laura (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Juan, Ángel A. (Universitat Politècnica de València. Departament d'Estadística Aplicada i Investigació Operativa)
In the context of increasing complexity in manufacturing and logistic systems, the combination of optimization and simulation can be considered a versatile tool for supporting managerial decision-making. [...]
2023 - 10.3390/math11071577
Mathematics, Vol. 11, Issue 7 (April 2023) , art. 1577
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4.
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16 p, 1.2 MB |
Dynamic Reactive Assignment of Tasks in Real-Time Automated Guided Vehicle Environments with Potential Interruptions
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Martin, Xabier A. (Universitat Politècnica de València. Departament d'Estadística Aplicada i Investigació Operativa) ;
Hatami, Sara (Universitat Politècnica de Catalunya. Departament de Gestió) ;
Calvet Liñan, Laura (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Peyman, Mohammad (Universitat Oberta de Catalunya. Departament d'Informàtica, Multimèdia i Telecomunicació) ;
Juan, Ángel A (Euncet Business School. Departament de Gestió)
An efficient management of production plants has to consider several external and internal factors, such as potential interruptions of the ongoing processes. Automated guided vehicles (AGVs) are becoming a widespread technology that offers many advantages. [...]
2023 - 10.3390/app13063708
Applied sciences (Basel), Vol. 13, Issue 6 (March 2023) , art. 3708
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5.
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17 p, 4.1 MB |
Enhancing Carsharing Experiences for Barcelona Citizens with Data Analytics and Intelligent Algorithms
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Herrera, Erika M. (Universitat Oberta de Catalunya. Departament d'Informàtica) ;
Calvet Liñan, Laura (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Ghorbani, Elnaz (Universitat Oberta de Catalunya. Departament d'Informàtica) ;
Panadero, Javier (Universitat Politècnica de Catalunya. Departament de Gestió) ;
Juan, Ángel A (Euncet Business School. Departament de Gestió)
Carsharing practices are spreading across many cities in the world. This paper analyzes real-life data obtained from a private carsharing company operating in the city of Barcelona, Spain. After describing the main trends in the data, machine learning and time-series analysis methods are employed to better understand citizens' needs and behavior, as well as to make predictions about the evolution of their demand for this service. [...]
2023 - 10.3390/computers12020033
Computers, Vol. 12, Issue 2 (February 2023) , art. 33
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6.
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19 p, 523.3 KB |
Optimizing Energy Consumption in Smart Cities' Mobility : Electric Vehicles, Algorithms, and Collaborative Economy
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Ghorbani, Elnaz (Universitat Oberta de Catalunya. Departament d'Informàtica) ;
Fluechter, Tristan (University College Dublin) ;
Calvet Liñan, Laura (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Ammouriova, Majsa (Universitat Oberta de Catalunya. Departament d'Informàtica) ;
Panadero, Javier (Euncet Business School. Departament de Gestió) ;
Juan, Ángel A (Universitat Politècnica de València. Departament d'Estadística Aplicada i Investigació Operativa)
Mobility and transportation activities in smart cities require an increasing amount of energy. With the frequent energy crises arising worldwide and the need for a more sustainable and environmental friendly economy, optimizing energy consumption in these growing activities becomes a must. [...]
2023, - 10.3390/en16031268
Energies, Vol. 16, Issue 3 (February 2023) , art. 1268
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7.
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22 p, 1.1 MB |
MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
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Block, Matthew S. (Mayo Clinic) ;
Vierkant, Robert A. (Mayo Clinic) ;
Rambau, Peter F. (Catholic University of Health and Allied Sciences-Bugando) ;
Winham, Stacey J. (Mayo Clinic) ;
Wagner, Philipp (Tübingen University Hospital) ;
Traficante, Nadia (the University of Melbourne) ;
Toloczko, Aleksandra (Pomeranian Medical University) ;
Tiezzi, Daniel G. (University of São Paulo) ;
Taran, Florin Andrei (Tübingen University Hospital) ;
Sinn, Peter (Heidelberg University Hospital (Alemanya)) ;
Sieh, Weiva (Icahn School of Medicine at Mount Sinai) ;
Sharma, Raghwa ;
Rothstein, Joseph H. (Icahn School of Medicine at Mount Sinai) ;
Ramon y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Paz-Ares, Luis (Hospital 12 de Octubre (Madrid)) ;
Oszurek, Oleg (Pomeranian Medical University) ;
Orsulic, Sandra (Cedars-Sinai Medical Center) ;
Ness, Roberta B. (University of Texas School of Public Health) ;
Nelson, Gregg (University of Calgary) ;
Modugno, Francesmary (Magee-Womens Research Institute and University of Pittsburgh Cancer Institute) ;
Menkiszak, Janusz (Pomeranian Medical University) ;
McGuire, Valerie (Stanford University School of Medicine) ;
McCauley, Bryan M. (Mayo Clinic) ;
Mack, Marie (University of Cambridge) ;
Lubinski, Jan (International Hereditary Cancer Center) ;
Longacre, Teri A. (Stanford University) ;
Li, Zheng (the Third Affiliated Hospital of Kunming Medical University (Yunnan Tumor Hospital)) ;
Lester, Jenny (Cedars-Sinai Medical Center) ;
Kennedy, Catherine J. (Westmead Hospital) ;
Kalli, Kimberly R. (Mayo Clinic) ;
Jung, Audrey Y. (German Cancer Research Center (DKFZ)) ;
Johnatty, Sharon E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Jimenez-Linan, Mercedes (Addenbrookes Hospital (Cambridge, Regne Unit)) ;
Jensen, Allan (Danish Cancer Society Research Center) ;
Intermaggio, Maria P. (University of New South Wales) ;
Hung, Jillian ;
Herpel, Esther (University of Heidelberg) ;
Hernandez, Brenda Y. (University of Hawaii) ;
Hartkopf, Andreas D. (Tübingen University Hospital) ;
Harnett, Paul R. ;
Ghatage, Prafull (University of Calgary) ;
García-Bueno, José M. (Complejo Hospitalario Universitario de Albacete) ;
Gao, Bo (University of Sydney) ;
Fereday, Sian ;
Eilber, Ursula (German Cancer Research Center (DKFZ)) ;
Edwards, Robert P. (University of Pittsburgh School of Medicine) ;
de Sousa, Christiani B. (University of São Paulo) ;
de Andrade, Jurandyr M. (University of São Paulo) ;
Chudecka-Glaz, Anita (Pomeranian Medical University) ;
Chenevix-Trench, Georgia ;
Cazorla, Alicia (Hospital Universitario Fundación Jiménez Díaz) ;
Brucker, Sara Y. (Tübingen University Hospital) ;
Bowtell, David D. ;
Green, A. ;
Webb, P. ;
De Fazio, Anna ;
Gertig, D. ;
Moore, S. ;
Harrap, K. ;
Sadkowsky, T. ;
Pandeya, N. ;
Malt, M. ;
Mellon, A. ;
Robertson, R. ;
Vanden Bergh, T. ;
Jones, M. ;
Mackenzie, P. ;
Maidens, J. ;
Nattress, K. ;
Chiew, Y.E. ;
Stenlake, A. ;
Sullivan, H. ;
Alexander, B. ;
Ashover, P. ;
Brown, S. ;
Corrish, T. ;
Green, L. ;
Jackman, L. ;
Ferguson, K. ;
Martin, K. ;
Martyn, A. ;
Ranieri, B. ;
White, J. ;
Jayde, V. ;
Mamers, P. ;
Bowes, L. ;
Galletta, L. ;
Giles, D. ;
Hendley, J. ;
Alsop, K. ;
Schmidt, T. ;
Shirley, H. ;
Ball, C. ;
Young, C. ;
Viduka, S. ;
Tran, H. ;
Bilic, Sanela ;
Glavinas, Lydia 700 1_ ;
Stuart-Harris, R. ;
Kirsten, F. ;
Rutovitz, J. ;
Clingan, P. ;
Glasgow, A. ;
Proietto, A. ;
Braye, S. ;
Otton, G. ;
Shannon, J. ;
Bonaventura, T. ;
Stewart, J. ;
Begbie, S. ;
Friedlander, M. ;
Bell, D. ;
Baron-Hay, S. ;
Ferrier, A. ;
Gard, G. ;
Nevell, D. ;
Pavlakis, N. ;
Valmadre, S. ;
Young, B. ;
Camaris, C. ;
Crouch, R. ;
Edwards, L. ;
Hacker, N. ;
Marsden, D. ;
Robertson, G. ;
Beale, P. ;
Beith, J. ;
Carter, J. ;
Dalrymple, C. ;
Houghton, R. ;
Russell, P. ;
Links, M. ;
Grygiel, J. ;
Hill, J. ;
Brand, A. ;
Byth, K. ;
Jaworski, R. ;
Wain, G. ;
Ward, B. ;
Papadimos, D. ;
Crandon, A. ;
Cummings, M. ;
Horwood, K. ;
Obermair, A. ;
Perrin, L. ;
Wyld, D. ;
Nicklin, J. ;
Davy, M. ;
Oehler, M.K. ;
Hall, C. ;
Dodd, T. ;
Healy, T. ;
Pittman, K. ;
Henderson, D. ;
Miller, J. ;
Pierdes, J. ;
Blomfield, P. ;
Challis, D. ;
McIntosh, R. ;
Parker, A. ;
Brown, B. ;
Rome, R. ;
Allen, D. ;
Grant, P. ;
Hyde, S. ;
Laurie, R. ;
Robbie, M. ;
Healy, D. ;
Jobling, T. ;
Manolitsas, T. ;
McNealage, J. ;
Rogers, P. ;
Susil, B. ;
Sumithran, E. ;
Simpson, I. ;
Phillips, K. ;
Rischin, D. ;
Fox, S. ;
Johnson, D. ;
Lade, S. ;
Loughrey, M. ;
O'Callaghan, N. ;
Murray, W. ;
Waring, P. ;
Billson, V. ;
Pyman, J. ;
Neesham, D. ;
Quinn, M. ;
Underhill, C. ;
Bell, R. ;
Ng, L.F. ;
Blum, R. ;
Ganju, V. ;
Hammond, I. ;
Leung, Y. ;
McCartney, A. ;
Buck, M. ;
Haviv, I. ;
Purdie, D. ;
Whiteman, D. ;
Zeps, N. ;
Alsop, Jennifer (University of Cambridge) ;
Whittemore, Alice S. (Stanford University School of Medicine) ;
Steed, Helen (Royal Alexandra Hospital) ;
Staebler, Annette (Tübingen University Hospital) ;
Moysich, Kirsten B. (Roswell Park Cancer Institute) ;
Menon, Usha (University College London) ;
Koziak, Jennifer M. (Alberta Health Services-Cancer Care) ;
Kommoss, Stefan (Tübingen University Hospital) ;
Kjaer, Susanne K. (University of Copenhagen) ;
Kelemen, Linda E. (Medical University of South Carolina and Hollings Cancer Center) ;
Karlan, Beth Y. (Cedars-Sinai Medical Center) ;
Huntsman, David G. (British Columbia Cancer Agency) ;
Høgdall, Estrid (University of Copenhagen) ;
Gronwald, Jacek (Pomeranian Medical University) ;
Goodman, Marc T. (Cedars-Sinai Medical Center) ;
Gilks, Blake (Vancouver General Hospital and University of British Columbia) ;
García, María José (Instituto de Salud Carlos III) ;
Fasching, Peter A. (University Hospital Erlangen (Alemanya)) ;
Deen, Suha (Nottingham University Hospitals NHS Trust (Regne Unit)) ;
Chang-Claude, Jenny (University Medical Center Hamburg-Eppendorf) ;
Candido dos Reis, Francisco J. (University of São Paulo) ;
Campbell, Ian (University of Melbourne) ;
Brenton, James D. (Cambridge Experimental Cancer Medicine Centre) ;
Benitez, Javier (Instituto de Salud Carlos III) ;
Pharoah, Paul D.P. (University of Cambridge) ;
Köbel, Martin (University of Calgary) ;
Ramus, Susan J. (Garvan Institute) ;
Goode, Ellen L. (Mayo Clinic) ;
Universitat Autònoma de Barcelona
To evaluate myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 (TLR4) expression in relation to clinical features of epithelial ovarian cancer, histologic subtypes, and overall survival. [...]
2018 - 10.1016/j.mayocp.2017.10.023
Mayo Clinic Proceedings, Vol. 93 Núm. 3 (january 2018) , p. 307-320
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11 p, 1.4 MB |
Prognostic gene expression signature for high-grade serous ovarian cancer
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Millstein, Joshua (University of Southern California) ;
Budden, Timothy (The University of Manchester) ;
Goode, Ellen L. (Mayo Clinic) ;
Anglesio, Michael (University of British Columbia) ;
Talhouk, Aline (University of British Columbia) ;
Intermaggio, Maria Paola (University of NSW Sydney) ;
Leong, Hueisan (Peter MacCallum Cancer Center) ;
Chen, Stephanie S. (Cedars-Sinai Medical Center) ;
Elatre, Wafaa A. (University of Southern California) ;
Gilks, Cyril Blake (University of British Columbia) ;
Nazeran, Tayyebeh M. (University of British Columbia) ;
Volchek, Mila (Royal Women's Hospital) ;
Bentley, Rex C. (Duke University Hospital) ;
Wang, Chen (Mayo Clinic) ;
Chiu, Derek S. (University of British Columbia) ;
Kommoss, Stefan (Tuebingen University Hospital) ;
Leung, Samuel C. Y. (University of British Columbia) ;
Senz, Janine (University of British Columbia) ;
Lum, Amy (University of British Columbia) ;
Chow, Veronica (University of British Columbia) ;
Sudderuddin, Hanwei (University of British Columbia) ;
Mackenzie, Robertson (University of British Columbia) ;
George, Joshy (The Jackson Laboratory for Genomic Medicine) ;
Fereday, Sian (University of Melbourne) ;
Hendley, Joy (University of Melbourne) ;
Traficante, Nadia (University of Melbourne) ;
Steed, Helen (Royal Alexandra Hospital) ;
Koziak, Jennifer M. (Alberta Health Services-Cancer Care) ;
Köbel, Martin (Foothills Medical Center) ;
McNeish, Iain (University of Glasgow) ;
Goranova, Teodora Evgenieva (University of Cambridge) ;
Ennis, Darren P. (University of Glasgow) ;
Macintyre, Geoff (University of Cambridge) ;
Silva De Silva, D. (University of Cambridge) ;
Ramon y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
García Donas, J. (HM Hospitales D Centro Integral Oncológico HM Clara Campal) ;
Hernando, Susana (Hospital Universitario Funcacion Alcorcon) ;
Rodriguez, Gustavo C. (University of Chicago) ;
Cushing-Haugen, Kara L. (Fred Hutchinson Cancer Research Center) ;
Harris, Holly Ruth (University of Washington) ;
Greene, Casey S. (University of Pennsylvania) ;
Zelaya, René A. (Geisel School of Medicine at Dartmouth) ;
Behrens, Sabine (German Cancer Research Center (DKFZ)) ;
Fortner, Renée T. (German Cancer Research Center (DKFZ)) ;
Sinn, Hans-Peter (Heidelberg University Hospital (Alemanya)) ;
Herpel, Esther (University Hospital and German Cancer Research Center) ;
Lester, Jenny (Cedars-Sinai Medical Center) ;
Lubinski, Jan (Pomeranian Medical University) ;
Oszurek, Oleg (Pomeranian Medical University) ;
Tołoczko, Aleksandra D. (Pomeranian Medical University) ;
Cybulski, Cezary (Pomeranian Medical University) ;
Menkiszak, Janusz Leszek (Pomeranian Medical University) ;
Pearce, Celeste Leigh (University of Southern California Norris Comprehensive Cancer Center) ;
Pike, Malcolm C. (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ;
Tseng, Chiuchen Cheng (University of Southern California) ;
Alsop, Jennifer (University of Cambridge) ;
Rhenius, Valerie (University of Cambridge) ;
Song, Hongan (University of Cambridge) ;
Jimenez-Liñan, Mercedes (Addenbrooke's Hospital NHS Trust) ;
Piskorz, Anna M. (University of Cambridge) ;
Gentry-Maharaj, Aleksandra (University College London) ;
Karpinskyj, Chloe (University College London) ;
Widschwendter, M. (University College London) ;
Singh, Naveena K. (Barts Health National Health Service Trust) ;
Kennedy, Catherine J. (Westmead Hospital) ;
Harnett, Paul R. (University of Sidney) ;
Gao, Bo (Westmead Hospital) ;
Johnatty, Sharon E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Sayer, Robyn A. (Westmead Hospital) ;
Boros, Jessica (Westmead Hospital) ;
Winham, Stacey J. (Mayo Clinic) ;
Keeney, Gary L. (Mayo Clinic) ;
Kaufmann, Scott H. (Mayo Clinic) ;
Larson, Melissa C. (Mayo Clinic) ;
Luk, Hugh W. (University of Hawaii Cancer Center) ;
Hernandez, Brenda Y. (University of Hawaii Cancer Center) ;
Thompson, Pamela J. (Cedars-Sinai Medical Center) ;
Wilkens, Lynne Ross (University of Hawaii Cancer Center) ;
Carney, Michael E. (University of Hawaii) ;
Trabert, Britton (National Cancer Institute) ;
Lissowska, Jolanta (M Sklodowska Curie National Research Institute of Oncology) ;
Brinton, Louise Annette (National Cancer Institute) ;
Sherman, Mark E. (Mayo Clinic College of Medicine) ;
Bodelón, Clara (National Cancer Institute) ;
Hinsley, Samantha (University of Glasgow) ;
Lewsley, Liz Anne (University of Glasgow) ;
Glasspool, Rosalind M. (University of Glasgow) ;
Banerjee, Susana (The Royal Marsden NHS Foundation Trust and Institute of Cancer Research) ;
Stronach, Euan A. (Imperial College London) ;
Haluska, Paul J. (Mayo Clinic) ;
Ray-Coquard, Isabelle Laure (Centre Leon Berard and University Claude Bernard Lyon 1) ;
Mahner, Sven (LMU Munich) ;
Winterhoff, Boris J. N. (University of Minnesota) ;
Slamon, Dennis J. (University of California at Los Angeles) ;
Levine, Douglas A. (NYU Langone Medical Center) ;
Kelemen, Linda E. (Medical University of South Carolina) ;
Benitez, Javier J. (Centro Nacional de Investigaciones Oncológicas) ;
Chang-Claude, J. (University Medical Center Hamburg-Eppendorf) ;
Gronwald, Jacek (Pomeranian Medical University) ;
Wu, Anna H. (University of Southern California) ;
Menon, Usha (MRC University College London) ;
Goodman, Marc T. (Cedars-Sinai Medical Center) ;
Schildkraut, Joellen M. (Emory University) ;
Wentzensen, Nicolas A. (National Cancer Institute) ;
Brown, Robert (Imperial College London) ;
Berchuck, Andrew (Duke University Hospital) ;
Gayther, Simon A. (Cedars-Sinai Medical Center) ;
García, M. J. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Henderson, Michelle J. (University of NSW Sydney) ;
Rossing, Mary Anne (University of Washington) ;
Beeghly-Fadiel, Alicia (Vanderbilt University School of Medicine) ;
Fasching, Peter Andreas (Friedrich-Alexander-University Erlangen-Nuremberg) ;
Orsulic, Sandra (Cedars-Sinai Medical Center) ;
Karlan, Beth Y. (Cedars-Sinai Medical Center) ;
Konecny, Gottfried Ewald (University of California at Los Angeles) ;
Huntsman, David G. (BC Cancer Research Centre) ;
Brenton, James D. (University of Cambridge) ;
Doherty, Jennifer Anne (University of Utah) ;
Pharoah, Paul D. P. (University of Cambridge) ;
Ramus, Susan (University of NSW Sydney) ;
Universitat Autònoma de Barcelona
Median overall survival (OS) for women with high-grade serous ovarian cancer (HGSOC) is ∼4 years, yet survival varies widely between patients. There are no well-established, gene expression signatures associated with prognosis. [...]
2020 - 10.1016/j.annonc.2020.05.019
Annals of oncology, Vol. 31 Núm. 9 (01 2020) , p. 1240-1250
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48 p, 1008.7 KB |
Data science, analytics and artificial intelligence in e-health : trends, applications and challenges
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Castaneda, Juliana (Universitat Oberta de Catalunya) ;
Calvet Liñan, Laura (Universitat Oberta de Catalunya) ;
Benito Rey, Sergio (Universitat Oberta de Catalunya) ;
Tondar, Abtin (Universitat Oberta de Catalunya) ;
Juan, Ángel A (Universitat Politècnica de València)
More than ever, healthcare systems can use data, predictive models, and intelligent algorithms to optimize their operations and the service they provide. This paper reviews the existing literature regarding the use of data science/analytics methods and artificial intelligence algorithms in healthcare. [...]
2023 - 10.57645/20.8080.02.2
SORT : statistics and operations research transactions, Vol. 47 Núm. 1 (2023) , p. 81-128
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