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Articles, 65 registres trobats
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Articles 65 registres trobats  1 - 10següentfinal  anar al registre:
1.
14 p, 2.2 MB Multiplex RNA-based detection of clinically relevant MET alterations in advanced non-small cell lung cancer / Aguado, Cristina (Quirón Dexeus University Hospital) ; Teixido, Cristina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Román, Ruth (Quirón Dexeus University Hospital) ; Reyes, Roxana (Hospital Clínic i Provincial de Barcelona) ; Giménez-Capitán, Ana (Quirón Dexeus University Hospital) ; Marin, Elba (Hospital Clínic i Provincial de Barcelona) ; Cabrera, Carlos (Dexeus University Hospital Quiron Salud Group) ; Viñolas, Nuria (Hospital Clínic i Provincial de Barcelona) ; Castillo, Sergi (Hospital General de Granollers) ; Muñoz, Silvia (Hospital General de Granollers) ; Arcocha, Ainara (Hospital Clínic i Provincial de Barcelona) ; López-Vilaró, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Sullivan, Ivana (Institut d'Investigació Biomèdica Sant Pau) ; Aldeguer, Erika (Quirón Dexeus University Hospital) ; Rodríguez, Sonia (Quirón Dexeus University Hospital) ; Moya, Irene (Dexeus University Hospital Quiron Salud Group) ; Viteri, Santiago (Quiron Salud Group) ; Cardona, Andrés Felipe (Clínica del Country) ; Palmero, Ramon (L'Hospitalet) ; Sainz, Cristina (CIBERONC) ; Mesa-Guzmán, Miguel (Universidad Pública de Navarra) ; Lozano, Maria D. (Universidad Pública de Navarra) ; Aguilar-Hernández, Andrés (Dexeus University Hospital Quiron Salud Group) ; Martínez-Bueno, Alejandro (Dexeus University Hospital Quiron Salud Group) ; González-Cao, María (Dexeus University Hospital Quiron Salud Group) ; Gonzalvo, Elena (Hospital Clínic i Provincial de Barcelona) ; Leenders, William P. J. (Radboud Institute for Molecular Life Sciences) ; Rosell, Rafael (Universitat Autònoma de Barcelona. Departament de Medicina) ; Montuenga, Luis M. (Universidad Pública de Navarra) ; Prat, Aleix (Hospital Clínic i Provincial de Barcelona) ; Molina-Vila, Miguel Angel (Quirón Dexeus University Hospital) ; Reguart, Noemi (Hospital Clínic i Provincial de Barcelona)
We studied MET alterations in 474 advanced non-small-cell lung cancer (NSCLC) patients by nCounter, an RNA-based technique. We identified 3% with MET Δex14 mRNA and 3. 5% with very-high MET mRNA expression, a surrogate of MET amplification. [...]
2020 - 10.1002/1878-0261.12861
Molecular Oncology, Vol. 15 (december 2020) , p. 350-363  
2.
19 p, 3.7 MB Nuclear RNA purification by flow cytometry to study nuclear processes in plants / Moro, Belen (Centre de Recerca en Agrigenòmica) ; Kisielow, Malgorzata (Zurich Flow Cytomtery Core Facility) ; Barragan Borrero, Veronica (Gregor Mendel Institute of Molecular Plant Biology) ; Bouet, Antoine (Centre de Recerca en Agrigenòmica) ; Brosnan, Christopher (University of Queensland, Brisbane) ; Bologna, Nicolás G. (Centre de Recerca en Agrigenòmica)
The nature of plant tissues has continuously hampered understanding of the spatio-temporal and subcellular distribution of RNA-guided processes. Here, we describe a universal protocol based on Arabidopsis to investigate subcellular RNA distribution from virtually any plant species using flow cytometry sorting. [...]
2021 - 10.1016/j.xpro.2021.100320
STAR Protocols, Vol. 2, Issue 1 (March 2021) , art. 100320  
3.
25 p, 5.5 MB Human sperm displays rapid responses to diet / Nätt, D. (Linköping University. Department of Clinical and Experimental Medicine. Division of Neurobiology) ; Kugelberg, U. (Linköping University. Department of Clinical and Experimental Medicine. Division of Neurobiology) ; Casas Masnou, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Nedstrand, E. (Linköping University. Department of Clinical and Experimental Medicine. Division of Obstetrics and Gynecology) ; Zalavary, S. (Linköping University. Department of Clinical and Experimental Medicine. Division of Obstetrics and Gynecology) ; Henriksson, P. (Linköping University. Department of Medical and Health Sciences. Division of Community Medicine) ; Nijm, C. (Linköping University. Department of Clinical and Experimental Medicine. Division of Obstetrics and Gynecology) ; Jäderquist, J. (Linköping University. Department of Clinical and Experimental Medicine. Division of Obstetrics and Gynecology) ; Sandborg, J. (Linköping University. Department of Medical and Health Sciences. Division of Community Medicine) ; Flinke, E. (Linköping University. Department of Medical and Health Sciences. Division of Community Medicine) ; Ramesh, R. (Linköping University. Department of Clinical and Experimental Medicine. Division of Neurobiology) ; Örkenby, L. (Linköping University. Department of Clinical and Experimental Medicine. Division of Neurobiology) ; Appelkvist, F. (Linköping University. Department of Clinical and Experimental Medicine. Division of Neurobiology) ; Lingg, T. (Linköping University. Department of Clinical and Experimental Medicine. Division of Neurobiology) ; Guzzi, N. (Lund University. Stem Cell Center. Department of Laboratory Medicine. Division of Molecular Hematology) ; Bellodi, C. (Lund University. Stem Cell Center. Department of Laboratory Medicine. Division of Molecular Hematology) ; Löf, M. (Linköping University. Department of Medical and Health Sciences. Division of Community Medicine) ; Vavouri, Tanya (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Öst, A. (Linköping University. Department of Clinical and Experimental Medicine. Division of Neurobiology) ; Universitat Autònoma de Barcelona
The global rise in obesity and steady decline in sperm quality are two alarming trends that have emerged during recent decades. In parallel, evidence from model organisms shows that paternal diet can affect offspring metabolic health in a process involving sperm tRNA-derived small RNA (tsRNA). [...]
2019 - 10.1371/journal.pbio.3000559
PLoS biology, Vol. 17 Núm. 12 (2019) , p. e3000559  
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11 p, 3.4 MB Identification of key sequence features required for microRNA biogenesis in plants / Rojas, Arantxa M.L. (Instituto de Biología Molecular y Celular de Rosario) ; Drusin, Salvador I. (Instituto de Biología Molecular y Celular de Rosario) ; Chorostecki, Uciel Pablo (Instituto de Investigación en Biomedicina. Instituto de Ciencia y Tecnología de Barcelona) ; Mateos, Julieta Lisa (Instituto de Fisiología, Biología Molecular y Neurociencias) ; Moro, Belen (Centre de Recerca en Agrigenòmica) ; Bologna, Nicolás (Centre de Recerca en Agrigenòmica) ; Bresso, Edgardo G. (Instituto de Biología Molecular y Celular de Rosario) ; Schapire, Arnaldo (Instituto de Biología Molecular y Celular de Rosario) ; Rasia, Rodolfo (Instituto de Biología Molecular y Celular de Rosario) ; Moreno, Diego M. (Universidad Nacional de Rosario. Departamento de Química-Física) ; Palatnik, Javier (Instituto de Biología Molecular y Celular de Rosario)
MicroRNAs (miRNAs) are endogenous small RNAs of ∼21 nt that regulate multiple biological pathways in multicellular organisms. They derive from longer transcripts that harbor an imperfect stem-loop structure. [...]
2020 - 10.1038/s41467-020-19129-6
Nature communications, Vol. 11 (October 2020) , art. 5320  
5.
19 p, 1.5 MB Analyzing the genomic and transcriptomic architecture of milk traits in Murciano-Granadina goats / Guan, Dailu (Centre de Recerca en Agrigenòmica) ; Landi, Vicenzo (Universidad de Córdoba. Departamento de Genética) ; Luigi Sierra, Maria Gracia (Centre de Recerca en Agrigenòmica) ; Delgado, Juan Vicente (Universidad de Córdoba. Departamento de Genética) ; Such, Xavier (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Castelló Farré, Anna (Centre de Recerca en Agrigenòmica) ; Cabrera Pane, Betlem (Centre de Recerca en Agrigenòmica) ; Mármol-Sánchez, Emilio (Centre de Recerca en Agrigenòmica) ; Fernández-Alvarez, Javier (Asociación Nacional de Criadores de Caprino de Raza Murciano-Granadina) ; De La Torre Casañas, José Luis (Universitat Autònoma de Barcelona. Servei de Granges i Camps Experimentals) ; Martinez, Amparo (Universidad de Córdoba. Departamento de Genética) ; Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Amills i Eras, Marcel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Background:In this study, we aimed to investigate the molecular basis of lactation as well as to identify the genetic factors that influence milk yield and composition in goats. To achieve these two goals, we have analyzed how the mRNA profile of the mammary gland changes in seven Murciano-Granadina goats at each of three different time points, i. [...]
2020 - 10.1186/s40104-020-00435-4
Journal of animal science and biotechnology, Vol. 11 (March 2020) , art. 35  
6.
14 p, 2.0 MB Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation / Diesch, Jeannine (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bywater, M.J. (QIMR Berghofer Medical Research Institute) ; Sanij, E. (Department of Pathology. University of Melbourne) ; Cameron, D.P. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Schierding, W. (Liggins Institute. The University of Auckland) ; Brajanovski, N. (Cancer Research Division. Peter MacCallum Cancer Centre) ; Son, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Sornkom, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Hein, N. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Evers, M. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Pearson, R.B. (Department of Biochemistry and Molecular Biology. University of Melbourne) ; McArthur, G.A. (Department of Medicine. St Vincent's Hospital. University of Melbourne) ; Ganley, A.R.D. (School of Biological Sciences. The University of Auckland) ; O'Sullivan, J.M. (Liggins Institute. The University of Auckland) ; Hannan, R.D. (School of Biomedical Sciences. University of Queensland) ; Poortinga, G. (Department of Medicine. St Vincent's Hospital. University of Melbourne) ; Universitat Autònoma de Barcelona
The three-dimensional organization of the genome contributes to its maintenance and regulation. While chromosomal regions associate with nucleolar ribosomal RNA genes (rDNA), the biological significance of rDNA-genome interactions and whether they are dynamically regulated during disease remain unclear. [...]
2019 - 10.1038/s42003-019-0284-y
Communications Biology, Vol. 2 Núm. 1 (january 2019) , p. 39  
7.
7 p, 979.5 KB Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer / Piqué, L. (Institut d'Investigació Biomèdica de Bellvitge) ; Martinez de Paz, A. (Institut d'Investigació Biomèdica de Bellvitge) ; Piñeyro, D. (Institut d'Investigació Biomèdica de Bellvitge) ; Martínez Cardús, Anna (Institut d'Investigació Biomèdica de Bellvitge) ; Castro de Moura, M. (Institut d'Investigació Biomèdica de Bellvitge) ; Llinàs-Arias, P. (Institut d'Investigació Biomèdica de Bellvitge) ; Setien, F. (Institut d'Investigació Biomèdica de Bellvitge) ; Gomez-Miragaya, J. (Institut d'Investigació Biomèdica de Bellvitge) ; Gonzalez-Suarez, E. (Institut d'Investigació Biomèdica de Bellvitge) ; Sigurdsson, S. (Department of Biochemistry and Molecular Biology. Biomedical Center) ; Jonasson, J.G. (Department of Pathology. Landspitali University Hospital) ; Villanueva, A. (Institut Català d'Oncologia) ; Vidal, A. (Hospital Universitari de Bellvitge) ; Davalos, V. (Institut d'Investigació Biomèdica de Bellvitge) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Human tumors show altered patterns of protein isoforms that can be related to the dysregulation of messenger RNA alternative splicing also observed in transformed cells. Although somatic mutations in core spliceosome components and their associated factors have been described in some cases, almost nothing is known about the contribution of distorted epigenetic patterns to aberrant splicing. [...]
2019 - 10.1038/s41388-019-0936-x
Oncogene, Vol. 38 Núm. 45 (july 2019) , p. 7106-7112  
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18 p, 4.0 MB Targeting OGG1 arrests cancer cell proliferation by inducing replication stress / Visnes, T. (Sintef Industry. Department of Biotechnology and Nanomedicine) ; Benítez-Buelga, C. (Karolinska Institutet. Department of Oncology and Pathology) ; Cázares-Körner, A. (Karolinska Institutet. Department of Oncology and Pathology) ; Sanjiv, K. (Karolinska Institutet. Department of Oncology and Pathology) ; Hanna, B.M.F. (Karolinska Institutet. Department of Oncology and Pathology) ; Mortusewicz, O. (Karolinska Institutet. Department of Oncology and Pathology) ; Rajagopal, V. (Karolinska Institutet. Department of Oncology and Pathology) ; Albers, J.J. (Karolinska Institutet. Department of Oncology and Pathology) ; Hagey, D.W. (Karolinska Institutet. Department of Laboratory Medicine) ; Bekkhus, T. (Karolinska Institutet. Department of Oncology and Pathology) ; Eshtad, S. (Karolinska Institutet. Department of Oncology and Pathology) ; Baquero, J.M. (Centro Nacional de Investigaciones Oncológicas (Madrid, Espanya)) ; Masuyer, G. (University of Bath. Department of Pharmacy and Pharmacology) ; Wallner, O. (Karolinska Institutet. Department of Oncology and Pathology) ; Müller, S. (Karolinska Institutet. Department of Oncology and Pathology) ; Pham, T. (Karolinska Institutet. Department of Oncology and Pathology) ; Göktürk, C. (Karolinska Institutet. Department of Oncology and Pathology) ; Rasti, A. (Karolinska Institutet. Department of Oncology and Pathology) ; Suman, S. (Karolinska Institutet. Department of Oncology and Pathologyt) ; Torres, Raul (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sarno, A. (Sintef Ocean. Department of Environment and New Resources) ; Wiita, E. (Karolinska Institutet. Department of Oncology and Pathology) ; Homan, E.J. (Karolinska Institutet. Department of Oncology and Pathology) ; Karsten, S. (Karolinska Institutet. Department of Oncology and Pathology) ; Marimuthu, K. (Karolinska Institutet. Department of Oncology and Pathology) ; Michel, M. (Karolinska Institutet. Department of Oncology and Pathology) ; Koolmeister, T. (Karolinska Institutet. Department of Oncology and Pathology) ; Scobie, M. (Karolinska Institutet. Department of Oncology and Pathology) ; Loseva, O. (Karolinska Institutet. Department of Oncology and Pathology) ; Almlöf, I. (Karolinska Institutet. Department of Oncology and Pathology) ; Unterlass, J.E. (Karolinska Institutet. Department of Oncology and Pathology) ; Pettke, A. (Karolinska Institutet. Department of Oncology and Pathology) ; Boström, J. (Karolinska Institutet. Department of Laboratory Medicine) ; Pandey, M. (University of Sheffield. Weston Park Cancer Centre) ; Gad, H. (University of Sheffield. Weston Park Cancer Centre) ; Herr, P. (University of Sheffield. Weston Park Cancer Centre) ; Jemth, A.S. (Karolinska Institutet. Department of Oncology and Pathology) ; El Andaloussi, S. (Karolinska Institutet. Department of Laboratory Medicine) ; Kalderén, C. (Karolinska Institutet. Department of Oncology and Pathology) ; Rodriguez-Perales, S. (Centro Nacional de Investigaciones Oncológicas (Madrid, Espanya)) ; Benítez, J. (Centro de Investigación Biomédica en Red de Enfermedades Raras-CIBERER (Madrid, Espanya)) ; Krokan, H.E. (Research and Innovation in Central Norway) ; Altun, M. (Karolinska Institutet. Department of Laboratory Medicine) ; Stenmark, P. (Lund University. Department of Experimental Medical Science.) ; Berglund, U.W. (Karolinska Institutet. Department of Oncology and Pathology) ; Helleday, T. (University of Sheffield.Weston Park Cancer Centre) ; Universitat Autònoma de Barcelona
Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e. g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise 8-oxoG. [...]
2021 - 10.1093/nar/gkaa1048
Nucleic acids research, Vol. 48 Núm. 21 (february 2021) , p. 12234-12251  
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9 p, 2.0 MB Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer / Rosselló-Tortella, Margalida (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Llinàs-Arias, P. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sakaguchi, Y. (Department of Chemistry and Biotechnology. Graduate School of Engineering. University of Tokyo) ; Miyauchi, K. (Department of Chemistry and Biotechnology. Graduate School of Engineering. University of Tokyo) ; Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Setién Beranda, Esteban Fernando (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Calleja-Cervantes, María Eréndira (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Piñeyro, David (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Martínez-Gómez, Jesús (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Guil, Sonia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Joshi, Ricky S. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Villanueva, A. (Institut d'Investigació Biomèdica de Bellvitge) ; Suzuki, T. (Department of Chemistry and Biotechnology. Graduate School of Engineering. University of Tokyo) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Transfer RNA (tRNA) activity is tightly regulated to provide a physiological protein translation, and tRNA chemical modifications control its function in a complex with ribosomes and messenger RNAs (mRNAs). [...]
2020 - 10.1073/pnas.2003358117
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117 Núm. 34 (25 2020) , p. 20785-20793  
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14 p, 5.6 MB The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances / Monteagudo-Sánchez, A. (Institut d'Investigació Biomèdica de Bellvitge) ; Hernandez Mora, J.R. (Institut d'Investigació Biomèdica de Bellvitge) ; Simon, C. (Department of Obstetrics and Gynecology. BIDMC. Harvard University) ; Burton, A. (Institute of Epigenetics and Stem Cells. Helmholtz Zentrum München) ; Tenorio, J. (CIBERER. Centro de Investigacion Biomedica en Red de Enfermedades Raras. ISCIII) ; Lapunzina, P. (ITHACA. European Reference Network on Rare Congenital Malformations and Rare Intellectual Disability) ; Clark, S. (Epigenetics Programme. The Babraham Institute) ; Esteller, M. (Centro de Investigacion Biomedica en Red Cancer (CIBERONC)) ; Kelsey, G. (Centre for Trophoblast Research. University of Cambridge) ; López-Siguero, J.P. (Servicio de Endocrinología Pediátrica. Hospital Carlos de Haya) ; De Nanclares, G.P. ((Epi)Genetics Laboratory. BioAraba Research Health Institute. Araba University Hospital) ; Torres-Padilla, M.E. (Institute of Epigenetics and Stem Cells. Helmholtz Zentrum München) ; Monk, D. (Biomedical Research Centre. University of East Anglia. Norwich Research Park) ; Universitat Autònoma de Barcelona
Genomic imprinting is an epigenetic process regulated by germline-derived DNA methylation that is resistant to embryonic reprogramming, resulting in parental origin-specific monoallelic gene expression. [...]
2020 - 10.1093/nar/gkaa837
Nucleic acids research, Vol. 48 Núm. 20 (18 2020) , p. 11394-11407  

Articles : 65 registres trobats   1 - 10següentfinal  anar al registre:
Llibres i col·leccions 1 registres trobats  
1.
8 p, 490.5 KB Mimicry technology : a versatile tool for small RNA suppression / Villar Martin, Luis Manuel (Centre de Recerca en Agrigenòmica) ; Rubio-Somoza, Ignacio (Centre de Recerca en Agrigenòmica)
A decade ago the discovery of the target mimicry regulatory process on the activity of a mature microRNA (miRNA) enabled for the first time the customized attenuation of miRNA activity in plants. That powerful technology was named MIMIC and was based on engineering the IPS1 long noncoding transcript to become complementary to the miRNA under study. [...]
New York : Humana Press, 2019 (Methods in molecular biology ; 1932) - 10.1007/978-1-4939-9042-9_18
Plant MicroRNAs, 2019, p. 27-38  

Documents de recerca 25 registres trobats  1 - 10següentfinal  anar al registre:
1.
203 p, 5.6 MB Human sperm transcriptome : characterization, biological relevance, and biomarker functionality / Corral Vázquez, Celia ; Anton, Ester, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
Se ha demostrado que la contribución del espermatozoide al embrión va más allá de la transmisión del genoma paterno. Diversos estudios han mostrado que el espermatozoide humano contiene una compleja población de RNAs implicados en funciones relacionadas con la fertilidad. [...]
The biological relevance of sperm contribution to the embryo has been shown to go beyond a mere transmission of the paternal genome. Several findings revealed that human spermatozoa carry a complex population of coding and non-coding RNAs with potential implications in multiple fertility-related pathways. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2020.  
2.
1 p, 195.9 KB RNA interference in designing new crops / Llargués Figueras ; Universitat Autònoma de Barcelona. Facultat de Veterinària
2019
Grau en Ciència i Tecnologia dels Aliments [974]  
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1 p, 15.7 MB The cryo-EM revolution : structural perspective of plicing / Rodà Llordés, Sergi ; Universitat Autònoma de Barcelona. Facultat de Biociències
2018
Grau en Bioquímica [814]  
4.
260 p, 5.2 MB Role of plant miRNAs in disease resistance / Salvador Guirao, Raquel ; San Segundo, Blanca, dir. ; Llugany i Ollé, Mercè, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia
Las plantas han desarrollado un potente sistema inmune para defenderse de la infección por patógenos. Este sistema requiere una delicada regulación de la expresión de genes codificantes para proteínas antimicrobianas y de señalización, factores de transcripción y proteínas de regulación hormonal. [...]
Plants have evolved a strong innate immunity system to defend themselves against pathogen infection. The defense responses require a fine-tune reprogramming of gene expression and transcriptional regulation of genes coding for antimicrobial and signaling proteins, transcription factors and proteins associated with hormone-regulation and defense responses. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2018.  
5.
251 p, 7.1 MB Identificación y caracterización funcional de microRNAs en cáncer de mama / Feliciano Aguirre, Andrea ; Lleonart Pajarin, Matilde, dir. ; Meseguer Navarro, Anna, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Los MicroRNAs (miRNAs) juegan un papel importante en diversos procesos biológicos y están emergiendo gradualmente como reguladores clave de la tumorigénesis y la progresión del tumor. Para explorar la desregulación de miRNAs en cáncer de mama, se analizó el perfil de expresión de 939 miRNAs en 50 pacientes con cáncer de mama. [...]
MicroRNAs (miRNAs) play important roles in diverse biological processes and are emerging as key regulators of tumorigenesis and tumor progression. To explore the dysregulation of miRNAs in breast cancer, a genome-wide expression profiling of 939 miRNAs was performed in 50 breast cancer patients. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2017.  
6.
209 p, 3.7 MB Function of microRNAs in plant innate immunity / Camargo Ramírez, Rosany del Carmen ; San Segundo, Blanca, dir. ; Tolrà Pérez, Roser, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia ; Universitat Autònoma de Barcelona. Centre de Recerca en Agrigenòmica
Esta tesis aborda el estudio de miARNs en la inmunidad innata en plantas. El trabajo se ha desarrollado en arroz (Capítulo I y Capítulo II) y en Arabidopsis (Capítulo III), En el capítulo I se describe la identificación y caracterización funcional de nuevos miARNs de arroz en su interacción con el hongo Magnaporthe oryzae. [...]
This thesis comprises the study of miRNAs in innate immunity in plants. The work has been developed in rice (Chapter I and Chapter II) and in Arabidopsis (Chapter III), model systems used in studies of functional genomics in monocotyledonous and dicotyledonous species, respectively. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2017.  
7.
1 p, 769.8 KB The role of MiRNA in the aetiology of polycystic ovarian syndrome / Planas Bonell, Sabina ; Anton, Ester, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Ciències Biomèdiques [832]  
8.
1 p, 2.7 MB Micrornas in Vet Medicine / Regordosa Vilajuana, Xavier ; Universitat Autònoma de Barcelona. Facultat de Veterinària
2016
Grau en Veterinària [955]  
9.
182 p, 4.8 MB Role of miR7695 in controlling OsNramp6 (Natural resistance-associated macrophage protein 6) expression and defense responses in rice plants / Peris Peris, Cristina ; San Segundo, Blanca, dir. (Institut de Biologia Molecular de Barcelona) ; Campo Sánchez, Sonia, dir. (Centre de Recerca en Agrigenòmica) ; Martos Arias, Soledad, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia
Los microARNs (mirARNs) son un clase de pequeños ARNs no codificantes que actúan como reguladores de la expresión génica, y juegan un papel determinante en procesos fisiológicos de las plantas, en los que se incluyen procesos del desarrollo, señalización hormonal, y procesos tanto de estrés abiótico como biótico. [...]
MicroRNAs (miRNAs) are key regulators of gene expression in a wide range of plant physiological processes, including developmental processes, hormone signaling, and responses to environmental stress, biotic and abiotic stress. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  
10.
219 p, 4.0 MB Virus del moteado de la parietaria (PMoV) / Martínez Moncayo, Carolina ; Galipienso Torregrosa, Luis, dir. ; Aparicio Herrero, Frederic, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia
En el primer capítulo de esta Tesis se ha realizado un estudio de la variabilidad genética y evolución del virus del moteado de la parietaria (PMoV). El análisis filogenético mostró que los aislados italianos se agrupaban en el clado I aislados españoles se agrupaban en los clados II, III y IV. [...]
In the first Thesis chapter , we have studied the genetic variation and evolution of parietaria mottle virus (PMoV). Phylogenetic analysis showed that the Italian isolates clustered in the clade I and the Spanish isolates clustered in the clades II, III and IV. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  

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