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Articles 27 records found  previous11 - 20next  jump to record: Search took 0.00 seconds. 
11.
15 p, 7.1 MB Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method / Merlo-Mas, Josep (Nanomol Technologies S.L.) ; Tomsen-Melero, Judit (Institut de Ciència de Materials de Barcelona) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; González Mira, Elisabet (Institut de Ciència de Materials de Barcelona) ; Font, Albert (Leanbio S.L.) ; Pedersen, Jannik N. (Aarhus University. Department of Chemistry and Interdisciplinary Nanoscience Center (iNANO) (Denmark)) ; García Aranda, Natalia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cristóbal-Lecina, Edgar (Institut de Química Avançada de Catalunya) ; Alcaina-Hernando, Marta (Nanomol Technologies S.L.) ; Mendoza, Rosa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Garcia-Fruitos, Elena (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lizarraga, Teresa (Leanbio S.L.) ; Resch, Susanne (BioNanoNet Forschungsgesellschaft mbH (Austria)) ; Schimpel, Christa (BioNanoNet Forschungsgesellschaft mbH (Austria)) ; Falk, Andreas (BioNanoNet Forschungsgesellschaft mbH (Austria)) ; Pulido, Daniel (Institut de Química Avançada de Catalunya) ; Royo, Miriam (Institut de Química Avançada de Catalunya) ; Schwartz, Simó (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Abasolo, Ibane (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pedersen, Jan Skov (Aarhus University. Department of Chemistry and Interdisciplinary Nanoscience Center (iNANO) (Denmark)) ; Danino, Dganit (Technion - Israel Institute of Technology. CryoEM Laboratory of Soft Matter) ; Soldevila, Andreu (Leanbio S.L.) ; Veciana i Miró, Jaume (Institut de Ciència de Materials de Barcelona) ; Sala, Santi (Nanomol Technologies S.L.) ; Ventosa, Nora (Institut de Ciència de Materials de Barcelona) ; Córdoba, Alba (Nanomol Technologies S.L.)
Fabry disease is a lysosomal storage disease arising from a deficiency of the enzyme α-galactosidase A (GLA). The enzyme deficiency results in an accumulation of glycolipids, which over time, leads to cardiovascular, cerebrovascular, and renal disease, ultimately leading to death in the fourth or fifth decade of life. [...]
2021 - 10.1016/j.supflu.2021.105204
The Journal of Supercritical Fluids, Vol. 173 (July 2021) , art. 105204  
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12.
16 p, 2.1 MB Latest advances in the development of eukaryotic vaults as targeted drug delivery systems / Muñoz-Juan, Amanda (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Carreño, Aida (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mendoza, Rosa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The use of smart drug delivery systems (DDSs) is one of the most promising approaches to overcome some of the drawbacks of drug-based therapies, such as improper biodistribution and lack of specific targeting. [...]
2019 - 10.3390/pharmaceutics11070300
Pharmaceutics, Vol. 11, Issue 7 (July 2019) , p. 300  
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13.
1 p, 682.3 KB Erratum to : Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins / Mamat, Uwe (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Wilke, Kathleen (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Bramhill, David (Bramhill Biological Consulting. East Moonstone Drive) ; Schromm, Andra Beate (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Lindner, Buko (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Kohl, Thomas Andreas (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Schaffer, Lana (The Scripps Research Institute) ; Head, Steven Robert (The Scripps Research Institute) ; Souvignier, Chad (Research Corporation Technologies (Tucson)) ; Meredith, Timothy Charles (Pennsylvania State University. Department of Biochemistry and Molecular Biology) ; Woodard, Ronald Wesley (University of Michigan. Department of Medicinal Chemistry)
2015 - 10.1186/s12934-015-0265-x
Microbial cell factories, Vol. 14, Issue 57 (2015)  
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14.
12 p, 5.7 MB Intracellular CXCR4 + cell targeting with T22-empowered protein-only nanoparticles / Unzueta Elorza, Ugutz (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Céspedes, María Virtudes (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Ferrer-Miralles, Neus (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Casanova Rigat, Isolda (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Cedano Rodríguez, Juan Antonio (Laboratory of Immunology, Regional Norte, Universidad de la Republica, Salto, Uruguay) ; Corchero Nieto, José Luis (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Domingo-Espin, Joan (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mangues, Ramon 1957- (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Cell-targeting peptides or proteins are appealing tools in nanomedicine and innovative medicines because they increase the local drug concentration and reduce potential side effects. CXC chemokine receptor 4 (CXCR4) is a cell surface marker associated with several severe human pathologies, including colorectal cancer, for which intracellular targeting agents are currently missing. [...]
2012 - 10.2147/IJN.S34450
International Journal of Nanomedicine, Vol. 7 (august 2012) , p. 4533-4544  
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15.
5 p, 470.7 KB Packaging protein drugs as bacterial inclusion bodies for therapeutic applications / Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Garcia-Fruitos, Elena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rinas, Ursula (Helmholtz-Zentrum für Infektionsforschung) ; Seras-Franzoso, Joaquin (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Kosoy, Ana (Janus Development SL) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
A growing number of insights on the biology of bacterial inclusion bodies (IBs) have revealed intriguing utilities of these protein particles. Since they combine mechanical stability and protein functionality, IBs have been already exploited in biocatalysis and explored for bottom-up topographical modification in tissue engineering. [...]
2012 - 10.1186/1475-2859-11-76
Microbial cell factories, Vol. 11 (June 2012) , art. 76  
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16.
5 p, 243.9 KB Biological activities of histidine-rich peptides; merging biotechnology and nanomedicine / Ferrer-Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Kumar, Pradeep (CSIR-Institute of Genomics and Integrative Biology) ; Cedano Rodríguez, Juan Antonio (Universidad de la República (Uruguay).) ; Gupta, Kailash C.. (CSIR-Indian Institute of Toxicology Research) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Histidine-rich peptides are commonly used in recombinant protein production as purification tags, allowing the one-step affinity separation of the His-tagged proteins from the extracellular media or cell extracts. [...]
2011 - 10.1186/1475-2859-10-101
Microbial cell factories, Vol. 10 (2011) , art. 101  
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17.
6 p, 314.6 KB Post-production protein stability : trouble beyond the cell factory / Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Being protein function a conformation-dependent issue, avoiding aggregation during production is a major challenge in biotechnological processes, what is often successfully addressed by convenient upstream, midstream or downstream approaches. [...]
2011 - 10.1186/1475-2859-10-60
Microbial cell factories, Vol. 10 (2011) , art. 60  
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18.
10 p, 1.7 MB Bacterial mimetics of endocrine secretory granules as immobilized in vivo depots for functional protein drugs / Céspedes, María Virtudes (Institut d'Investigació Biomèdica Sant Pau) ; Fernández Caparrós, Yolanda (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Unzueta Elorza, Ugutz (Institut d'Investigació Biomèdica Sant Pau) ; Mendoza, Rosa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Seras-Franzoso, Joaquin (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Sánchez Chardi, Alejandro (Universitat Autònoma de Barcelona. Servei de Microscòpia) ; Álamo, Patricia (Institut d'Investigació Biomèdica Sant Pau) ; Toledo-Rubio, Verónica (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Ferrer-Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Institut d'Investigació Biomèdica Sant Pau) ; Schwartz Jr, Simó (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Abasolo, Ibane (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Mangues, Ramon 1957- (Institut d'Investigació Biomèdica Sant Pau) ; Villaverde Corrales, Antonio, (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona
In the human endocrine system many protein hormones including urotensin, glucagon, obestatin, bombesin and secretin, among others, are supplied from amyloidal secretory granules. These granules form part of the so called functional amyloids, which within the whole aggregome appear to be more abundant than formerly believed. [...]
2016 - 10.1038/srep35765
Scientific reports, Vol. 6 Núm. 35765 (October 2016) , p. 1-10  
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19.
47 p, 816.8 KB Highly versatile polyelectrolyte complexes for improving the enzyme replacement therapy of lysosomal storage disorders / Giannotti, M. I. (Universitat de Barcelona. Departament de Química Física) ; Abasolo, Ibane (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Oliva, Mireia (Universitat de Barcelona. Departament de Farmàcia i Tecnologia Farmacèutica, i Fisicoquímica) ; Andrade, Fernanda (Universitat de Barcelona. Departament de Farmàcia i Tecnologia Farmacèutica, i Fisicoquímica) ; García Aranda, Natalia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Melgarejo, Marta (Parc Científic de Barcelona) ; Pulido, Daniel (Parc Científic de Barcelona) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Fernández Caparrós, Yolanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Royo, Miriam (Parc Científic de Barcelona) ; García Parajó, María F.. (Institut de Ciències Fotòniques) ; Sanz, Fausto (Parc Científic de Barcelona) ; Schwartz, Simó Jr (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Lysosomal storage disorders are currently treated by enzyme replacement therapy (ERT) through the direct administration of the unprotected recombinant protein to the patients. Herein we present an ionically crosslinked polyelectrolyte complex (PEC) composed of trimethyl chitosan (TMC) and -galactosidase A (GLA), the defective enzyme in Fabry disease, with the capability of directly targeting endothelial cells by incorporating peptide ligands containing the RGD sequence. [...]
2016 - 10.1021/acsami.6b08356
ACS applied materials & interfaces, Vol. 8 Núm 39 (Octubre 2016) , p. 25741-25752  
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20.
56 p, 354.6 KB Engineering protein self-assembling in protein-based nanomedicines for drug delivery and gene therapy / Ferrer-Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rodríguez-Carmona, Escarlata (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Garcia-Fruitos, Elena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Lack of targeting and improper biodistribution are major flaws in current drug-based therapies that prevent reaching high local concentrations of the therapeutic agent. Such weaknesses impose the administration of high drug doses, resulting in undesired side effects, limited efficacy and enhanced production costs. [...]
2015 - 10.3109/07388551.2013.833163
Critical reviews in biotechnology, Vol. 35 (2015)
6 documents
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Articles : 27 records found   previous11 - 20next  jump to record:
See also: similar author names
2 Corchero, J. L.
1 Corchero, J.L.
1 Corchero, José Luís
17 Corchero, Juan Manuel
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