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10 p, 825.0 KB |
Neuropeptide-S-receptor deficiency affects sex-specific modulation of safety learning by pre-exposure to electric stimuli
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Kreutzmann, Judith.C. (Department of Systems Physiology of Learning. Leibniz Institute for Neurobiology) ;
Khalil, Radwa (Otto-von-Guericke University Magdeburg. Institute for Pharmacology & Toxicology) ;
Köhler, Jana C. (Otto-von-Guericke University Magdeburg. Center of Behavioral Brain Sciences) ;
Mayer, Dana (Otto-von-Guericke University Magdeburg. Institute for Pharmacology & Toxicology) ;
Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fendt, Markus (Otto-von-Guericke University Magdeburg. Center of Behavioral Brain Sciences)
Neuropeptide S (NPS) is a neuropeptide involved in the regulation of fear. Because safety learning is impaired in patients suffering from anxiety-related psychiatric disorders, and polymorphisms of the human neuropeptide S receptor (NPSR) gene have also been associated with anxiety disorders, we wanted to investigate whether NPSR-deficiency interferes with safety learning, and how prior stress would affect this type of learning. [...]
2020 -  10.1111/gbb.12621
Genes, Brain and Behavior, Vol. 19 Núm. 3 (January 2020) , p. e12621
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13 p, 668.0 KB |
Glucocorticoid-based pharmacotherapies preventing PTSD
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Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Velasco, Eric Raúl (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Monari, Sílvia (Geneva University Hospitals. Department of Psychiatry) ;
Cano, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Cardoner, N. (Narcís) (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Sandi, Carmen (École Polytechnique Fédérale de Lausanne (Suïssa). Brain Mind Institute) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Perez-Caballero, Laura (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Posttraumatic stress disorder (PTSD) is a highly disabling psychiatric condition that may arise after exposure to acute and severe trauma. It is a highly prevalent mental disorder worldwide, and the current treatment options for these patients remain limited due to low effectiveness. [...]
2023 - 10.1016/j.neuropharm.2022.109344
Neuropharmacology, Vol. 224 (2023) , 109344
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17 p, 3.3 MB |
PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus
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Velasco García, Eric Raúl (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Flores, África (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Senabre, Eric (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Gomez-Gomez, A. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Torres, A. (Hospital Clínic i Provincial de Barcelona) ;
Roca, A. (Hospital Clínic i Provincial de Barcelona) ;
Norrholm, S. (Wayne State University. Department of Psychiatry and Behavioral Neuroscience) ;
Newman, Emily L. (McLean Hospital. Department of Psychiatry. Harvard Medical School) ;
Das, P. (Department of Neuroscience. Albert Einstein College of Medicine) ;
Ross, R.A. (Department of Neuroscience. Albert Einstein College of Medicine) ;
Lori, Adriana (Emory University) ;
Pozo, Oscar J (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ressler, Kerry J. (McLean Hospital. Department of Psychiatry. Harvard Medical School) ;
Garcia-Esteve, L.L. (Hospital Clínic i Provincial de Barcelona) ;
Jovanovic, T. (Wayne State University. Department of Psychiatry and Behavioral Neuroscience) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Exposure to traumatic stress can lead to fear dysregulation, which has been associated with posttraumatic stress disorder (PTSD). Previous work showed that a polymorphism in the PACAP-PAC1R (pituitary adenylate cyclase-activating polypeptide) system is associated with PTSD risk in women, and PACAP (ADCYAP1)-PAC1R (ADCYAP1R1) are highly expressed in the hypothalamus. [...]
2022 - 10.1038/s41467-022-31442-w
Nature communications, Vol. 13 Núm. 1 (december 2022) , p. 4374
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19 p, 3.5 MB |
Sex differences in fear memory consolidation via Tac2 signaling in mice
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Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Velasco García, Eric Raúl (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Soto-Faguás, C. M. (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Gomez-Gomez, A. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Perez-Caballero, Laura (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Molina, P. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Pozo, Oscar J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Saura Antolín, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Institut de Neurociències)
Memory formation is key for brain functioning. Uncovering the memory mechanisms is helping us to better understand neural processes in health and disease. Moreover, more specific treatments for fear-related disorders such as posttraumatic stress disorder and phobias may help to decrease their negative impact on mental health. [...]
2021 - 10.1038/s41467-021-22911-9
Nature communications, Vol. 12 (may 2021)
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16 p, 1.8 MB |
A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction
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Domingo-Rodriguez, Laura (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Ruiz de Azua, Inigo (Johannes Gutenberg University (Mainz, Alemanya). University Medical Center) ;
Dominguez, Eduardo (Centre de Regulació Genòmica) ;
Senabre, Eric (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Serra, Irene (Instituto Cajal (Consejo Superior de Investigaciones Científicas)) ;
Kummer, Sami (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Navandar, Mohit (Johannes Gutenberg University. Faculty of Biology and Center of Computational Sciences) ;
Baddenhausen, Sarah (University Medical Center of the Johannes Gutenberg University Mainz. Institute of Physiological Chemistry) ;
Hofmann, Clementine (Johannes Gutenberg University Mainz. Focus Program Translational Neuroscience) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Gerber, Susanne (Johannes Gutenberg University. Faculty of Biology and Center of Computational Sciences) ;
Navarrete, Marta (Instituto Cajal (Consejo Superior de Investigaciones Científicas)) ;
Dierssen, Mara (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Lutz, Beat (Leibniz Institute for Resilience Research, Mainz, Germany) ;
Martín-García, Elena 1975- (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Maldonado, Rafael 1961- (Institut Hospital del Mar d'Investigacions Mèdiques)
Food addiction is linked to obesity and eating disorders and is characterized by a loss of behavioral control and compulsive food intake. Here, using a food addiction mouse model, we report that the lack of cannabinoid type-1 receptor in dorsal telencephalic glutamatergic neurons prevents the development of food addiction-like behavior, which is associated with enhanced synaptic excitatory transmission in the medial prefrontal cortex (mPFC) and in the nucleus accumbens (NAc). [...]
2020 - 10.1038/s41467-020-14458-y
Nature communications, Vol. 11 (february 2020)
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12 p, 3.7 MB |
Stable, concentrated, biocompatible, and defect-free graphene dispersions with positive charge
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Shin, Yuyoung (University of Manchester. Department of Chemistry) ;
Vranic, Sandra (University of Manchester. Nanomedicine Lab) ;
Just-Baringo, Xavier (University of Manchester. Department of Chemistry) ;
Gali, Sai Manoj (Institut Català de Nanociència i Nanotecnologia) ;
Kisby, Thomas (University of Manchester. National Graphene Institute) ;
Chen, Yingxian (University of Manchester. Nanomedicine Lab) ;
Gkoutzidou, Alexandra (University of Manchester. Department of Materials) ;
Prestat, Eric (SciTech Daresbury Campus. SuperSTEM Laboratory) ;
Beljonne, David (Institut Català de Nanociència i Nanotecnologia) ;
Larrosa, Igor (University of Manchester. Department of Chemistry) ;
Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ;
Casiraghi, Cinzia (University of Manchester. Department of Chemistry)
The outstanding properties of graphene offer high potential for biomedical applications. In this framework, positively charged nanomaterials show better interactions with the biological environment, hence there is strong interest in the production of positively charged graphene nanosheets. [...]
2020 - 10.1039/d0nr02689a
Nanoscale, Vol. 12, Issue 23 (June 2020) , p. 12383-12394
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10 p, 1.0 MB |
Protecting a diamond quantum memory by charge state control
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Pfender, Matthias (Stuttgart Research Center of Photonic Engineering) ;
Aslam, Nabeel (Stuttgart Research Center of Photonic Engineering) ;
Simon, Patrick (Technische Universität München. Walter Schottky Institut) ;
Antonov, Denis (Stuttgart Research Center of Photonic Engineering) ;
Thiering, Gergő (Budapest University of Technology and Economics. Department of Atomic Physics) ;
Burk, Sina (Stuttgart Research Center of Photonic Engineering) ;
De Oliveira, Felipe Fávaro (Stuttgart Research Center of Photonic Engineering) ;
Denisenko, Andrej (Stuttgart Research Center of Photonic Engineering) ;
Fedder, Helmut (Swabian Instruments GmbH) ;
Meijer, Jan (Universität Leipzig. Institute for Experimental Physics II) ;
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia) ;
Gali, Adam (Budapest University of Technology and Economics. Department of Atomic Physics) ;
Teraji, Tokuyuki (National Institute for Materials Science (Tsukuba, Japó)) ;
Isoya, Junichi (University of Tsukuba. Research Center for Knowledge Communities) ;
Doherty, Marcus William (Australian National University. Laser Physics Centre) ;
Alkauskas, Audrius (Center for Physical Sciences and Technology (Vilnius, Lituània)) ;
Gallo, Alejandro (Max Planck Institute for Solid State Research) ;
Grüneis, Andreas (Max Planck Institute for Solid State Research) ;
Neumann, Philipp (Stuttgart Research Center of Photonic Engineering) ;
Wrachtrup, Jörg (Stuttgart Research Center of Photonic Engineering)
In recent years, solid-state spin systems have emerged as promising candidates for quantum information processing. Prominent examples are the nitrogen-vacancy (NV) center in diamond, phosphorus dopants in silicon (Si:P), rare-earth ions in solids, and V-centers in silicon-carbide. [...]
2017 - 10.1021/acs.nanolett.7b01796
Nano letters, Vol. 17, issue 10 (Oct. 2017) , p. 5931-5937
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15 p, 1.3 MB |
Ni enrichment and stability of Al-free garnierite solid-solutions : A thermodynamic approach
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Galí, S. (Universitat de Barcelona. Departament de Cristal·lografia, Mineralogia i Dipòsits Minerals) ;
Soler Matamala, Josep Maria (Institut de Diagnòstic Ambiental i Estudis de l'Aigua) ;
Proenza, J. A. (Universitat de Barcelona. Departament de Cristal·lografia, Mineralogia i Dipòsits Minerals) ;
Lewis, J. F. (The George Washington University. Department of Earth and Environmental Sciences) ;
Cama Robert, Jordi (Institut de Diagnòstic Ambiental i Estudis de l'Aigua) ;
Tauler, E. (Universitat de Barcelona. Departament de Cristal·lografia, Mineralogia i Dipòsits Minerals)
Garnierites represent significant Ni ore minerals in the many Ni-laterite deposits worldwide. The occurrence of a variety of garnierite minerals with variable Ni content poses questions about the conditions of their formation. [...]
2012 - 10.1346/CCMN.2012.0600203
Clays and Clay Minerals, Vol. 60, Núm. 2 (2012) , p. 121-135
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