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Invasive Treatment Strategy in Adults With Frailty and Non-ST-Segment Elevation Myocardial Infarction
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Sanchis, Juan (Universitat de València) ;
Bueno, Héctor (Universidad Complutense de Madrid) ;
García-Blas, Sergio (Universitat de València) ;
Alegre, Oriol (Hospital Universitari de Bellvitge) ;
Martí Sánchez, David (Universidad de Alcalá) ;
Martínez-Sellés, Manuel (Hospital Universitario Gregorio Marañón) ;
Domínguez-Pérez, Laura (Universidad Complutense de Madrid) ;
Díez-Villanueva, Pablo (Hospital Universitario La Princesa) ;
Barrabés, Jose A. (Hospital Universitari Vall d'Hebron) ;
Marín, Francisco (Instituto Murciano de Investigación Biosanitaria) ;
Villa, Adolfo (Southeast University Hospital) ;
Sanmartín, Marcelo (Hospital Universitario Ramón y Cajal) ;
Llibre, Cinta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sionis, Alessandro (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Carol, Antoni (Hospital Moisés Broggi) ;
Fernández-Cisnal, Agustín (Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares) ;
Calvo Barriuso, Elena (Hospital Universitari de Bellvitge) ;
Morales, María José (Universidad Alcalá) ;
Elízaga, Jaime (University Hospital Gregorio Marañón) ;
Gómez, Iván (Universidad Complutense de Madrid) ;
Alfonso, Fernando (Instituto de Investigación Hospital Universitario de la Princesa) ;
García del Blanco, Bruno (Hospital Universitari Vall d'Hebron) ;
Formiga, Francesc (Hospital Universitari de Bellvitge) ;
Núñez, Eduardo (Hospital Clínic Universitari (València)) ;
Núñez, Julio (Hospital Clínic Universitari (València)) ;
Ariza-Solé, Albert (Hospital Universitari de Bellvitge) ;
Universitat Autònoma de Barcelona
Does a routine invasive strategy improve midterm outcomes in adults with frailty and acute non-ST-segment elevation myocardial infarction (NSTEMI)? In this secondary analysis of a randomized clinical trial of 167 patients with frailty and NSTEMI, a routine invasive strategy, when compared with a conservative strategy, did not reduce the number of days alive at a median follow-up of 1113 days. [...]
2024 -  10.1001/jamanetworkopen.2024.0809
JAMA network open, Vol. 7 (march 2024)
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17 p, 4.1 MB |
NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy
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Hurtado-Navarro, Laura (Instituto Murciano de Investigación Biosanitaria) ;
Cuenca-Zamora, Ernesto José (Instituto Murciano de Investigación Biosanitaria) ;
Zamora, Lurdes (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bellosillo Paricio, Beatriz (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Such, Esperanza (Hospital Universitari i Politècnic La Fe (València)) ;
Soler-Espejo, Eva (Hospital Universitario Morales-Meseguer, Centro Regional de Hemodonación, Murcia) ;
Martínez-Banaclocha, Helios (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Hernández-Rivas, Jesús Maria (Universidad de Salamanca) ;
Marco-Ayala, Javier (Hospital Universitario Morales-Meseguer. Murcia) ;
Martínez-Alarcón, Laura (Instituto Murciano de Investigación Biosanitaria) ;
Linares-Latorre, Lola (Fundació Institut Valencià d'Oncologia) ;
García-Ávila, Sara (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Amat-Martínez, Paula (Hospital Clínic Universitari (València)) ;
González, Teresa (Universidad de Salamanca) ;
Arnan, Montserrat (Institut Català D'Oncologia (ICO)-Hospital Duran I Reynals. IDIBELL) ;
Pomares-Marín, Helena (Institut Català D'Oncologia (ICO)-Hospital Duran I Reynals. IDIBELL) ;
Carreño-Tarragona, Gonzalo (Hospital 12 de Octubre (Madrid)) ;
Chen-Liang, Tzu Hua (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Herranz, María T. (Hospital Universitario Morales Meseguer) ;
García-Palenciano, Carlos (Hospital Clínico Universitario Virgen de La Arrixaca) ;
Morales, María Luz (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Jerez, Andrés (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Lozano, María L. (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Teruel-Montoya, Raúl (Universidad Católica San Antonio (UCAM)) ;
Pelegrín, Pablo (University of Murcia) ;
Ferrer-Marín, Francisca (Universidad Católica San Antonio (UCAM))
Chronic myelomonocytic leukemia (CMML) is frequently associated with mutations in the rat sarcoma gene (RAS), leading to worse prognosis. RAS mutations result in active RAS-GTP proteins, favoring myeloid cell proliferation and survival and inducing the NLRP3 inflammasome together with the apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), which promote caspase-1 activation and interleukin (IL)-1β release. [...]
2023 - 10.1016/j.xcrm.2023.101329
Cell Reports Medicine, Vol. 4 Núm. 12 (december 2023)
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6 p, 9.9 MB |
Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL
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Lahera, Antonio (Area of Genetics and Genomics. IIS Fundación Jiménez Díaz) ;
Vela Martín, Laura (Area of Genetics and Genomics. IIS Fundación Jiménez Díaz) ;
López Nieva, Pilar (Institute for Molecular Biology-IUBM. Universidad Autónoma de Madrid) ;
Salgado Sánchez, Rocío Nieves (Cytogenetics Service. Hospital Universitario Fundación Jiménez Díaz) ;
Rodriguez-Perales, Sandra (Molecular Cytogenetics & Genome Editing Unit. Human Cancer Genetics Program. Centro Nacional de Investigaciones Oncologicas) ;
Torres-Ruiz, Rocío (Advanced Therapy Unit. Instituto de Investigación Sanitaria Fundación Jiménez Díaz) ;
López Lorenzo, José L. (Hospital Universitario Fundación Jiménez Díaz) ;
Cornago, Javier (Division of Hematology and Hemotherapy. IIS Fundación Jiménez Díaz) ;
Llamas, Pilar (Division of Hematology and Hemotherapy. IIS Fundación Jiménez Díaz) ;
Fernández Navarro, Pablo (Networking Biomedical Research Centre of Epidemiology and Public Health) ;
Sánchez Domínguez, Rebeca (Networking Biomedical Research Centre of Rare Diseases) ;
Segovia, José C. (Networking Biomedical Research Centre of Rare Diseases) ;
Sastre, Isabel (Department of Genome Dynamics and Function. Centro de Biología Molecular Severo Ochoa. Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid) ;
Cobos Fernández, María Á. (Medical Oncology Department. Hospital Universitario 12 de Octubre) ;
Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Santos Hernández, Javier (Institute for Molecular Biology-IUBM. Universidad Autónoma de Madrid) ;
Fernández Piqueras, José (Institute for Molecular Biology-IUBM. Universidad Autónoma de Madrid) ;
Villa Morales, María (Institute for Molecular Biology-IUBM. Universidad Autónoma de Madrid)
2023 - 10.1111/bjh.18901
British Journal of Haematology, Vol. 202 Núm. 3 (august 2023) , p. 693-698
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14 p, 1.5 MB |
Seals', 'bitches', 'vixens', and other zoomorphic insults: the animalisation of women as an expression of misogyny in the Spanish Manosphere
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Lacalle Zalduendo, María Rosario (Universitat Autònoma de Barcelona) ;
Gómez Morales, Beatriz María (Universitat de Lleida) ;
Vicent-Ibáñez, Mireia (Universidad Complutense de Madrid) ;
Narvaiza Amengual, Sara
The animalisation of women is a recurrent strategy of dehumanisation in Manosphere discourses. Its normalisation as a social phenomenon and its popularity are rooted in short and sententious genres (proverbs, sayings, etc. [...]
2024 - 10.1080/23311983.2023.2298056
Cogent Arts & Humanities, Vol. 11 Núm. 1 (2024) , article 2298056
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14 p, 1.7 MB |
Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination : Secondary analysis of the randomised CombiVacS study
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García-Pérez, Javier (Instituto de Salud Carlos III) ;
González-Pérez, María (Instituto de Salud Carlos III) ;
Castillo de la Osa, María (Instituto de Salud Carlos III) ;
Borobia, Alberto M. (Universidad Autónoma de Madrid) ;
Castaño, Luis (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Bertrán, María Jesús (Hospital Clínic i Provincial de Barcelona) ;
Campins Martí, Magda (Hospital Universitari Vall d'Hebron) ;
Portolés, Antonio (Universidad Complutense de Madrid) ;
Lora, David (Universidad Complutense de Madrid) ;
Bermejo, Mercedes (Instituto de Salud Carlos III) ;
Conde, Patricia (Instituto de Salud Carlos III) ;
Hernández-Gutierrez, Lourdes (Instituto de Salud Carlos III) ;
Carcas, Antonio (Hospital Universitario La Paz (Madrid)) ;
Arana-Arri, Eunate (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Tortajada, Marta (Hospital Clínic i Provincial de Barcelona) ;
Fuentes Camps, Inmaculada (Hospital Universitari Vall d'Hebron) ;
Ascaso, Ana (Hospital Clínico San Carlos (Madrid)) ;
García-Morales, María Teresa (Universidad Complutense de Madrid) ;
Erick de la Torre-Tarazona, Humberto (Instituto de Salud Carlos III) ;
Arribas, Jose (Hospital Universitario La Paz (Madrid)) ;
Imaz-Ayo, Natale (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mellado-Pau, Eugènia (Hospital Clínic i Provincial de Barcelona) ;
Agustí Escasany, M. Antònia (Hospital Universitari Vall d'Hebron) ;
Pérez-Ingidua, Carla (Hospital Clínico San Carlos (Madrid)) ;
Gómez de la Cámara, Agustín (Universidad Complutense de Madrid) ;
Ochando, Jordi (Instituto de Salud Carlos III) ;
Belda-Iniesta, Cristobal (Instituto de Salud Carlos III) ;
Frías, Jesús (Hospital Universitario La Paz (Madrid)) ;
Alcami, Jose (Instituto de Salud Carlos III) ;
Pérez-Olmeda, Mayte (Instituto de Salud Carlos III) ;
Universitat Autònoma de Barcelona
The CombiVacS study was designed to assess immunogenicity and reactogenicity of the heterologous ChAdOx1-S/BNT162b2 combination, and 14-day results showed a strong immune response. The present secondary analysis addresses the evolution of humoral and cellular response up to day 180. [...]
2022 - 10.1016/j.eclinm.2022.101529
EClinicalMedicine, Vol. 50 (july 2022)
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15 p, 1.4 MB |
Critical role of interleukin (IL)-17 in inflammatory and immune disorders : An updated review of the evidence focusing in controversies
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Ruiz de Morales, José María G. (Universidad de León) ;
Puig, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Daudén, Esteban (Hospital Universitario de la Princesa (Madrid)) ;
Cañete, Juan D. (Hospital Clínic i Provincial de Barcelona) ;
Pablos, José Luis (Hospital Universitario 12 de Octubre (Madrid)) ;
Martín, Antonio Oliveira (Hospital Universitario La Paz (Madrid)) ;
Juanatey, Carlos González (Hospital Universitario Lucus Augusti (Lugo)) ;
Adan Civera, Alfredo (Hospital Clínic i Provincial de Barcelona) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Borruel, Natalia (Hospital Universitari Vall d'Hebron) ;
Ortí, Guillermo (Vall d'Hebron Institut d'Oncologia) ;
Holgado-Martín, Esther (Ruber Internacional) ;
Garcia-Vidal, Carolina (Hospital Clínic i Provincial de Barcelona) ;
Vizcaya-Morales, Cynthia (Novartis Pharma) ;
Martín-Vázquez, Víctor (Novartis Farmacéutica) ;
González-Gay, Miguel Ángel (Universidad de Cantabria)
Interleukin 17 (IL-17) is a proinflammatory cytokine that has been the focus of intensive research because of its crucial role in the pathogenesis of different diseases across many medical specialties. [...]
2020 - 10.1016/j.autrev.2019.102429
Autoimmunity Reviews, Vol. 19 Núm. 1 (january 2020) , p. 102429
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15 p, 942.2 KB |
A growth modulation index-based geistra score as a new prognostic tool for trabectedin efficacy in patients with advanced soft tissue sarcomas : A Spanish group for sarcoma research (GEIS) retrospective study
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Martínez-Trufero, Javier (Hospital Universitario Miguel Servet (Saragossa)) ;
Sande-González, Luis Miguel de (Hospital Universitario de León) ;
Luna, Pablo (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Martín-Broto, Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Alvarez, Rosa (Hospital General Universitario Gregorio Marañón) ;
Marquina, Gloria (Hospital Universitario Clínico San Carlos (Madrid)) ;
Diaz-Beveridge, Roberto (Hospital Universitari i Politècnic La Fe (València)) ;
Poveda, Andrés (Instituto Valenciano de Oncologia) ;
Cano, Juana María (Hospital General de Ciudad Real) ;
Cruz-Jurado, Josefina (Hospital Universitario Canarias) ;
López Pousa, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Salgado, María Angeles Vaz (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Valverde-Morales, Claudia Maria. (Hospital Universitari Vall d'Hebron) ;
Sevilla, Isabel (Universitarios Regional y Virgen de la Victoria de Málaga) ;
Martínez-García, Jerónimo (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Rubio-Casadevall, Jordi (Institut Català d'Oncologia) ;
de Juan Ferre, Ana (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Carrasco, Juan Antonio (Hospital Álvaro Cunqueiro (Vigo)) ;
Moura, David S. (Instituto de Biomedicina de Sevilla) ;
Gurruchaga-Sotes, Ibon (Hospital Universitario Miguel Servet (Saragossa)) ;
Gutiérrez, Antonio (Hospital Universitari Son Espases (Palma de Mallorca, Balears))
The aim of this study was to identify an easily reliable prognostic score that selects the subset of advanced soft tissue sarcoma (ASTS) patients with a higher benefit with trabectedin in terms of time to progression and overall survival. [...]
2021 - 10.3390/cancers13040792
Cancers, Vol. 13 Núm. 4 (february 2021) , p. 1-15
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Epidemiology of taeniosis/cysticercosis in Europe, a systematic review : Western Europe
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Laranjo-González, Minerva (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Devleesschauwer, Brecht (Universitat Rovira i Virgili. Facultat de Medicina i Ciències de la Salut) ;
Trevisan, Chiara (University of Copenhagen. Department of Veterinary and Animal Sciences) ;
Allepuz Palau, Alberto (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Sotiraki, Smaragda (Veterinary Research Institute) ;
Abraham, Annette (University of Oslo. Department of Community Medicine and Global Health) ;
Afonso, Mariana Boaventura (Secretaria Regional de Agricultura e Pescas. Divisão de Proteção Veterinária e Pecuária) ;
Blocher, Joachim (Academic Teaching Hospital Feldkirch. Institute for Acute Neurology and Stroke) ;
Cardoso, Luís (University of Trás-os-Montes e Alto Douro. Department of Veterinary Sciences) ;
Correia da Costa, José Manuel (University of Porto. Center for the Study of Animal Science) ;
Dorny, Pierre (Institute of Tropical Medicine. Department of Biomedical Sciences) ;
Gabriël, Sarah (Ghent University. Department of Veterinary Public Health and Food Safety) ;
Gomes, Jacinto (National Institute for Agrarian and Veterinary Research) ;
Gómez-Morales, María Ángeles (Istituto Superiore di Sanità. European Union Reference Laboratory for Parasites) ;
Jokelainen, Pikka (Estonian University of Life Sciences. Department of Basic Veterinary Sciences and Population Medicine) ;
Kaminski, Miriam (Technical University Munich. Department of Neurology) ;
Krt, Brane (University of Ljubljana. Institute for Microbiology and Parasitology) ;
Magnussen, Pascal (University of Copenhagen. Department of Veterinary and Animal Sciences) ;
Robertson, Lucy J. (Norwegian University of Life Sciences. Department of Food Safety and Infection Biology) ;
Schmidt, Veronika (University of Oslo. Department of Community Medicine and Global Health) ;
Schmutzhard, Erich (NICU Medical University Innsbruck. Department of Neurology) ;
Smit, G. Suzanne A. (Université catholique de Louvain. Institute of Health and Society) ;
Šoba, Barbara (University of Ljubljana. Institute of Microbiology and Immunology) ;
Stensvold, Christen Rune (Statens Serum Institut. Infectious Disease Preparedness) ;
Starič, Jože (University of Ljubljana. Clinic for reproduction and large animals) ;
Troell, Karin (National Veterinary Institute) ;
Rataj, Aleksandra Vergles (University of Ljubljana. Institute for Microbiology and Parasitology) ;
Vieira-Pinto, Madalena (Animal and Veterinary Research Centre) ;
Vilhena, Manuela (Universidade de Évora. Instituto de Ciências Agrárias e Ambientais Mediterrânicas) ;
Wardrop, Nicola Ann (University of Southampton. Geography and Environment) ;
Winkler, Andrea S. (University of Oslo. Department of Community Medicine and Global Health) ;
Dermauw, Veronique (Institute of Tropical Medicine. Department of Biomedical Sciences)
Taenia solium and Taenia saginata are zoonotic parasites of public health importance. Data on their occurrence in humans and animals in western Europe are incomplete and fragmented. In this study, we aimed to update the current knowledge on the epidemiology of these parasites in this region. [...]
2017 - 10.1186/s13071-017-2280-8
Parasites & vectors, Vol. 10 (july 2017)
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