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10 p, 1.6 MB |
Gut microbial dysbiosis in patients with Cushing's disease in long-term remission. Relationship with cardiometabolic risk
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Valassi, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Manichanh, Chaysavanh (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Amodru, Vincent (Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER)) ;
Fernández, Pedro González (Cruces University Hospital, Bilbao) ;
Gaztambide, Sonia (Cruces University Hospital, Bilbao) ;
Yañez, Francisca (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martel-Duguech, Luciana (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Puig Domingo, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Webb, Susan M. (Universitat Autònoma de Barcelona. Departament de Medicina)
Patients with Cushing's disease (CD) in remission maintain an increased cardiovascular risk. Impaired characteristics of gut microbiome (dysbiosis) have been associated with several cardiometabolic risk factors. [...]
2023 -  10.3389/fendo.2023.1074757
Frontiers in Endocrinology, Vol. 14 (june 2023)
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11 p, 1.8 MB |
Guselkumab-Treated Patients with Plaque Psoriasis Who Achieved Complete Skin Clearance for ≥ 156 Consecutive Weeks : A Post-Hoc Analysis From the VOYAGE 1 Clinical Trial
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Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Costanzo, Antonio (Humanitas Clinical and Research Center IRCCS) ;
de Jong, Elke M. G. J. (Radboud University Medical Center) ;
Torres, Tiago (University of Porto) ;
Warren, Richard B. (The University of Manchester) ;
Wapenaar, Robert (Janssen-Cilag BV (Breda, Països Baixos)) ;
Wegner, Sven (Janssen-Cilag GmbH (Neuss, Alemanya)) ;
Gorecki, Patricia (Janssen-Cilag Ltd (High Wycombe, Regne Unit)) ;
Gramiccia, Talia (Janssen-Cilag SpA (Milà, Itàlia)) ;
Jazra, Maria (Janssen-Cilag (París, França)) ;
Buyze, Jozefien (Janssen Pharmaceutica NV (Beerse, Bèlgica)) ;
Conrad, Curdin (University of Lausanne) ;
Universitat Autònoma de Barcelona
Treatment of moderate-to-severe plaque psoriasis with biologics, such as guselkumab, has demonstrated greater efficacy over traditional non-biologic treatments. However, given patient diversity, greater understanding of the relationship between patient characteristics, positive clinical outcomes, and long-term response to biologics is crucial for optimizing treatment choices. [...]
2023 - 10.1007/s40257-023-00816-1
American Journal of Clinical Dermatology, Vol. 25 (october 2023) , p. 315-325
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10 p, 673.5 KB |
Treatment of Psoriasis Patients with Latent Tuberculosis Using IL-17 and IL-23 Inhibitors : A Retrospective, Multinational, Multicentre Study
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Torres, Tiago (University of Porto, Portugal) ;
Chiricozzi, Andrea (Università Cattolica del Sacro Cuore, Rome, Italy) ;
Puig Sanz, Lluís (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Lé, Ana Maria (Centro Académico Clínico ICBAS - CHP, Porto, Portugal) ;
Marzano, Angelo Valerio (Università degli Studi di Milano, Italy) ;
Dapavo, Paolo (University of Turin, Italy) ;
Dauden, Esteban (Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa (IIS-IP), Madrid) ;
Carrascosa, Jόse-Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lazaridou, Elizabeth (Aristotle University School of Medicine, Thessaloniki, Greece) ;
Duarte, Gleison (Instituto Bahiano de Imunoterapias-IBIS, Salvador, Brazil) ;
Carvalho, André V. E. (Hospital Moinhos de Vento, Porto Alegre, Brazil) ;
Romiti, Ricardo (University of São Paulo, Brazil) ;
Rompoti, Natalia (University of Athens, 'A. Sygros' Hospital for Skin and Venereal Diseases, Athens, Greece) ;
Teixeira, Laetitia (Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Portugal) ;
Abreu, Miguel (University of Porto, Portugal) ;
Ippoliti, Elena (Università Cattolica del Sacro Cuore, Rome, Italy) ;
Maronese, Carlo Alberto (Università degli Studi di Milano, Italy) ;
Llamas-Velasco, Mar (Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa (IIS-IP)) ;
Vilarrasa-Rull, Eva (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
del Alcázar, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Daponte, Athina-Ioanna (Aristotle University School of Medicine, Thessaloniki, Greece) ;
Papoutsaki, Marina (University of Athens, 'A. Sygros' Hospital for Skin and Venereal Diseases, Athens, Greece) ;
Carugno, Andrea (ASST Papa Giovanni XXIII, Bergamo, Italy) ;
Bellinato, Francesco (University Hospital of Verona, Italy) ;
Gisondi, Paolo (University Hospital of Verona, Italy) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Tuberculosis has a major global impact. Immunocompetent hosts usually control this disease, resulting in an asymptomatic latent tuberculosis infection (LTBI). Because TNF inhibitors increase the risk of tuberculosis reactivation, current guidelines recommend tuberculosis screening before starting any biologic drug, and chemoprophylaxis if LTBI is diagnosed. [...]
2024 - 10.1007/s40257-024-00845-4
American Journal of Clinical Dermatology, Vol. 25, Num. 2 (march 2024) , p. 333-342
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16 p, 1.2 MB |
Brodalumab Versus Guselkumab in Patients with Moderate-to-Severe Psoriasis with an Inadequate Response to Ustekinumab : A Randomized, Multicenter, Double-Blind Phase 4 Trial (COBRA)
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Reich, Kristian (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ;
Bianchi, Luca (U.O.S.D. di Dermatologia Fondazione PTV Policlinico Tor Vergata, Rome, Italy) ;
Khemis, Abdallah (Polyclinique Saint George, Groupe KANTYS, Nice, France) ;
Maul, Julia-Tatjana (University of Zürich) ;
Tsianakas, Athanasios (Fachklinik Bad Bentheim, Bad Bentheim, Germany) ;
Schempp, Christoph M. (University of Freiburg, Germany) ;
Petersen, Kim (LEO Pharma A/S, Ballerup, Denmark) ;
Noergaard, Mia M. (LEO Pharma A/S, Ballerup, Denmark) ;
Puig Sanz, Lluís (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Despite improved treatment options for plaque psoriasis within the last decades, some patients still have an inadequate response to treatment. Direct clinical evaluation between therapies used after biologic failure could facilitate physicians' choice of treatment. [...]
2024 - 10.1007/s13555-023-01092-x
Dermatology and Therapy, Vol. 14 (february 2024) , p. 453-468
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12 p, 848.7 KB |
Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients : what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder?
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Baeza, Inmaculada (Hospital Clínic i Provincial de Barcelona) ;
de la Serna, Elena (Hospital Clínic i Provincial de Barcelona) ;
Mezquida, Gisela (Hospital Clínic i Provincial de Barcelona) ;
Cuesta, Manuel J. (Complejo Hospitalario de Navarra) ;
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona) ;
Amoretti, Silvia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lobo, Antonio (Universidad de Zaragoza) ;
González-Pinto, Ana (Hospital Universitario de Alava) ;
Díaz-Caneja, Covadonga M. (Hospital General Universitario Gregorio Marañón) ;
Corripio, Iluminada (Institut d'Investigació Biomèdica Sant Pau) ;
Valli, Isabel (King's College London) ;
Puig, Olga (Hospital Clínic i Provincial de Barcelona) ;
Mané, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Bioque, Miquel (Hospital Clínic i Provincial de Barcelona) ;
Ayora, Miriam (Hospital General Universitario Gregorio Marañón) ;
Bernardo, Miquel (Hospital Clínic i Provincial de Barcelona) ;
Castro-Fornieles, Josefina (Hospital Clínic i Provincial de Barcelona) ;
Garcia Rizo, Clemente (Hospital Clínic i Provincial de Barcelona) ;
González-Díaz, Jairo (Hospital Clínic i Provincial de Barcelona) ;
Grasa, Eva (Institut d'Investigació Biomèdica Sant Pau) ;
Roldán, Alejandra (Institut d'Investigació Biomèdica Sant Pau) ;
Casanovas, Francesc (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Toll, Alba (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Verdolini, Norma (Hospital Clínic i Provincial de Barcelona) ;
Sagué-Vilabella, Maria (Hospital Clínic i Provincial de Barcelona) ;
Sugranyes, Gisela (Hospital Clínic i Provincial de Barcelona) ;
Ilzarbe, Daniel (Hospital Clínic i Provincial de Barcelona) ;
Contreras, Fernando (Institut d'Investigació Biomèdica de Bellvitge) ;
Universitat Autònoma de Barcelona
To assess the role of age (early onset psychosis-EOP < 18 years vs. adult onset psychosis-AOP) and diagnosis (schizophrenia spectrum disorders-SSD vs. bipolar disorders-BD) on the duration of untreated psychosis (DUP) and prodromal symptoms in a sample of patients with a first episode of psychosis. [...]
2023 - 10.1007/s00787-023-02196-7
European child and adolescent psychiatry, Vol. 33 (april 2023) , p. 799-810
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9 p, 490.3 KB |
Leishmania Infection in Wild Lagomorphs and Domestic Dogs in North-East Spain
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Cabezón Ponsoda, Óscar (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Martínez-Orellana, Pamela (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Puig Ribas, Maria (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Baptista, Catarina Jota (Egas Moniz Center for Interdisciplinary Research) ;
Gassó, Diana (Universitat de Lleida. Escola Tècnica Superior d'Enginyeria Agrària) ;
Velarde, Roser (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Solano Gallego, Laia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Leishmania infantum is a zoonotic protozoan parasite transmitted by phlebotomine sandflies. Dogs are the main reservoir for human infections. In recent years, outbreaks of human leishmaniasis have been reported in different regions of Spain associated with the Iberian hare and European rabbit. [...]
2024 - 10.3390/ani14071080
Animals, Vol. 14 (april 2024)
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2 p, 292.1 KB |
Corrigendum : The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases(Front. Immunol., (2023), 14, (1191782), 10.3389/fimmu.2023.1191782)
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Navarro-Compán, Victoria (Hospital Universitario La Paz (Madrid)) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Ramírez, Julio (Hospital Clínic i Provincial de Barcelona) ;
Llamas-Velasco, Mar (Hospital Universitario de la Princesa (Madrid)) ;
Fernández-Carballido, Cristina (Hospital Universitario San Juan de Alicante) ;
Almodóvar, Raquel (Hospital Universitario Fundación Alcorcón) ;
Pinto, José Antonio (Complejo Hospitalario Universitario de A Coruña) ;
Galíndez-Aguirregoikoa, Eva (Hospital Universitario de Basurto) ;
Zarco, Pedro (Hospital Universitario Fundación Alcorcón) ;
Joven, Beatriz (Hospital 12 de Octubre (Madrid)) ;
Gratacós, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Juanola, Xavier (Hospital Universitari de Bellvitge) ;
Blanco, Ricardo (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Arias-Santiago, Salvador (Universidad de Granada) ;
Sanz Sanz, Jesús (Hospital Universitario Puerta del Hierro Majadahonda) ;
Queiro, Ruben (Hospital Universitario Central de Asturias) ;
Cañete, Juan D. (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
In the published article, there was an error in Table 1 as published. The cell corresponding to ixekizumab in HS must be yellow rather than green, since it is not approved for that indication, nor has phase 3 clinical development been published. [...]
2023 - 10.3389/fimmu.2023.1332177
Frontiers in immunology, Vol. 14 (2023) , p. 1332177
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10 p, 1.3 MB |
Ruthenium Complexes with Chiral bis-Pinene Ligands : an Array of Subtle Structural Diversity
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Vaquer Malia, Lydia (Institut Català d'Investigació Química) ;
Poater, Albert (Universitat de Girona) ;
De Tovar Villanueva, Jonathan (Universitat Autònoma de Barcelona. Departament de Química) ;
García-Antón, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ;
Solà i Puig, Miquel (Universitat de Girona. Departament de Química) ;
Llobet Dalmases, Antoni (Universitat Autònoma de Barcelona. Departament de Química) ;
Sala Román, Xavier (Universitat Autònoma de Barcelona. Departament de Química)
A new chiral derivative of the N,N-bis(2-pyridylmethyl)ethylamine (bpea) ligand, Me-pinene[5,6]bpea [(−)-L1], has been prepared from a new aldehyde building block [Me-pinene-aldehyde, (−)-4] arising from the monoterpene chiral pool. [...]
2013 - 10.1021/ic302678b
Inorganic Chemistry, Vol. 52, Issue 9 (May 2013) , p. 4985-4992
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